ON THE COVER
Confocal microscopy image of the proximity ligation signals (red) between the central CRISPR enzyme Cas9 and the universal SUMO E2 conjugase UBC9, in human epithelial HK-2 cell line. UBC9 physically interacts with Cas9 in cells' nuclei (blue, DAPI).

Image © 2022 Ergünay et al.