Research Article
Open Access
β-arrestin1 promotes tauopathy by transducing GPCR signaling, disrupting microtubules and autophagy
View ORCID ProfileJung-AA Woo Correspondence email, Yan Yan, Teresa R Kee, Sara Cazzaro, Kyle C McGill Percy, Xinming Wang, Tian Liu, View ORCID ProfileStephen B Liggett, David E Kang
Jung-AA Woo
1Department of Pathology, Case Western Reserve University, School of Medicine, Cleveland, OH, USA
Roles: Conceptualization, Resources, Data curation, Software, Formal analysis, Supervision, Funding acquisition, Validation, Investigation, Visualization, Methodology, Project administration, Writing—original draft, review, and editing
Yan Yan
1Department of Pathology, Case Western Reserve University, School of Medicine, Cleveland, OH, USA
2Department of Molecular Medicine, University of South Florida, College of Medicine, Tampa, FL, USA
Roles: Validation, Investigation, Methodology, Writing—review and editing
Teresa R Kee
1Department of Pathology, Case Western Reserve University, School of Medicine, Cleveland, OH, USA
2Department of Molecular Medicine, University of South Florida, College of Medicine, Tampa, FL, USA
Roles: Data curation, Validation, Investigation, Methodology, Writing—review and editing
Sara Cazzaro
1Department of Pathology, Case Western Reserve University, School of Medicine, Cleveland, OH, USA
2Department of Molecular Medicine, University of South Florida, College of Medicine, Tampa, FL, USA
Roles: Data curation, Validation, Investigation, Methodology, Writing—review and editing
Kyle C McGill Percy
1Department of Pathology, Case Western Reserve University, School of Medicine, Cleveland, OH, USA
Roles: Data curation, Validation, Investigation, Methodology, Writing—review and editing
Xinming Wang
1Department of Pathology, Case Western Reserve University, School of Medicine, Cleveland, OH, USA
Roles: Data curation, Validation, Investigation, Methodology, Writing—review and editing
Tian Liu
1Department of Pathology, Case Western Reserve University, School of Medicine, Cleveland, OH, USA
Roles: Data curation, Validation, Visualization, Methodology, Writing—review and editing
Stephen B Liggett
3Department of Molecular Pharmacology and Physiology, University of South Florida, College of Medicine, Tampa, FL, USA
Roles: Resources, Validation, Investigation, Writing—review and editing
David E Kang
1Department of Pathology, Case Western Reserve University, School of Medicine, Cleveland, OH, USA
4Louis Stokes Cleveland VA Medical Center, Cleveland, OH, USA
Roles: Conceptualization, Resources, Funding acquisition, Project administration, Writing—original draft, review, and editing
Published 3 December 2021. DOI: 10.26508/lsa.202101183
Reduced β-arrestin1 mitigates tauopathy in vivo
Jung-AA Woo, Yan Yan, Teresa R Kee, Sara Cazzaro, Kyle C McGill Percy, Xinming Wang, Tian Liu, Stephen B Liggett, David E Kang
Life Science Alliance Dec 2021, 5 (3) e202101183; DOI: 10.26508/lsa.202101183
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Volume 5, No. 3
March 2022
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