Research Article

Open Access
Loss of SET1/COMPASS methyltransferase activity reduces lifespan and fertility in Caenorhabditis elegans
Matthieu Caron, Loïc Gely, Steven Garvis, Annie Adrait, View ORCID ProfileYohann Couté, View ORCID ProfileFrancesca Palladino Correspondence email, View ORCID ProfilePaola Fabrizio Correspondence email
Matthieu Caron
1Laboratory of Biology and Modelling of the Cell, Ecole Normale Supérieure de Lyon, CNRS UMR5239, INSERM U1210, Université de Lyon, Lyon, France
Roles: Conceptualization, Formal analysis, Supervision, Investigation, Visualization, Writing—review and editing
Loïc Gely
1Laboratory of Biology and Modelling of the Cell, Ecole Normale Supérieure de Lyon, CNRS UMR5239, INSERM U1210, Université de Lyon, Lyon, France
Roles: Formal analysis, Investigation, Visualization
Steven Garvis
1Laboratory of Biology and Modelling of the Cell, Ecole Normale Supérieure de Lyon, CNRS UMR5239, INSERM U1210, Université de Lyon, Lyon, France
Roles: Formal analysis, Investigation, Writing—editing
Annie Adrait
2University of Grenoble Alpes, INSERM, CEA, UMR BioSanté U1292, CNRS, CEA, FR2048, Grenoble, France
Roles: Formal analysis, Data curation, Investigation
Yohann Couté
2University of Grenoble Alpes, INSERM, CEA, UMR BioSanté U1292, CNRS, CEA, FR2048, Grenoble, France
Roles: Formal analysis, Data curation, Investigation
Francesca Palladino
1Laboratory of Biology and Modelling of the Cell, Ecole Normale Supérieure de Lyon, CNRS UMR5239, INSERM U1210, Université de Lyon, Lyon, France
Roles: Conceptualization, Funding acquisition, Project administration, Writing—original draft, review, and editing
Paola Fabrizio
1Laboratory of Biology and Modelling of the Cell, Ecole Normale Supérieure de Lyon, CNRS UMR5239, INSERM U1210, Université de Lyon, Lyon, France
Roles: Conceptualization, Project administration, Validation, Formal analysis, Supervision, Investigation, Visualization, Writing—original draft, review, and editing
Published 10 December 2021. DOI: 10.26508/lsa.202101140
SET1/COMPASS is required for normal lifespan in C. elegans
Matthieu Caron, Loïc Gely, Steven Garvis, Annie Adrait, Yohann Couté, Francesca Palladino, Paola Fabrizio
Life Science Alliance Dec 2021, 5 (3) e202101140; DOI: 10.26508/lsa.202101140
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Volume 5, No. 3
March 2022
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