Table of Contents

Research Articles

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  Open Access

  Transcriptomics reveals immune-metabolism disorder in acute-on-chronic liver failure in rats

  Hozeifa M Hassan, Qun Cai, Xi Liang, Jiaojiao Xin, Keke Ren, Jing Jiang, Dongyan Shi, Yingyan Lu, Tan Li, Yuxin Shang, Lulu He, Xi Chen, Suwan Sun, Peng Li, Beibei Guo, Jiaxian Chen, Hui Yang, Wen Hu, Xin Chen, Jun Li

  Hozeifa M Hassan ... Jun Li

  Published 1 December 2021
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  Open Access

  Fms-like tyrosine kinase 3 is a regulator of the cardiac side population in mice

  Giacomo Della Verde, Michika Mochizuki, Vera Lorenz, Julien Roux, Lifen Xu, Leandra Ramin-Wright, Otmar Pfister, Gabriela M Kuster

  Giacomo Della Verde ... Gabriela M Kuster

  Published 13 December 2021
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  Open Access

  Artemisinin-independent inhibitory activity of Artemisia sp. infusions against different Plasmodium stages including relapse-causing hypnozoites

  Kutub Ashraf, Shahin Tajeri, Christophe-Sébastien Arnold, Nadia Amanzougaghene, Jean-François Franetich, Amélie Vantaux, Valérie Soulard, Mallaury Bordessoulles, Guillaume Cazals, Teun Bousema, Geert-Jan van Gemert, Roger Le Grand, Nathalie Dereuddre-Bosquet, Jean-Christophe Barale, Benoit Witkowski, Georges Snounou, Romain Duval, Cyrille Y Botté, Dominique Mazier

  Kutub Ashraf ... Dominique Mazier

  Published 2 December 2021
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  Open Access

  Bis-choline tetrathiomolybdate prevents copper-induced blood–brain barrier damage

  Sabine Borchard, Stefanie Raschke, Krzysztof M Zak, Carola Eberhagen, Claudia Einer, Elisabeth Weber, Sandra M Müller, Bernhard Michalke, Josef Lichtmannegger, Albrecht Wieser, Tamara Rieder, Grzegorz M Popowicz, Jerzy Adamski, Martin Klingenspor, Andrew H Coles, Ruth Viana, Mikkel H Vendelbo, Thomas D Sandahl, Tanja Schwerdtle, Thomas Plitz, Hans Zischka

  Sabine Borchard ... Hans Zischka

  Published 2 December 2021
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  Open Access

  Exosomes/microvesicles target SARS-CoV-2 via innate and RNA-induced immunity with PIWI-piRNA system

  Shoeb Ikhlas, Afia Usman, Dongkyeong Kim, Dongsheng Cai

  Shoeb Ikhlas ... Dongsheng Cai

  Published 3 December 2021
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  Open Access

  β-arrestin1 promotes tauopathy by transducing GPCR signaling, disrupting microtubules and autophagy

  Jung-AA Woo, Yan Yan, Teresa R Kee, Sara Cazzaro, Kyle C McGill Percy, Xinming Wang, Tian Liu, Stephen B Liggett, David E Kang

  Jung-AA Woo ... David E Kang

  Published 3 December 2021
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  Open Access

  Loss of SET1/COMPASS methyltransferase activity reduces lifespan and fertility in Caenorhabditis elegans

  Matthieu Caron, Loïc Gely, Steven Garvis, Annie Adrait, Yohann Couté, Francesca Palladino, Paola Fabrizio

  Matthieu Caron ... Paola Fabrizio

  Published 10 December 2021
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  Open Access

  Amyloid-like aggregating proteins cause lysosomal defects in neurons via gain-of-function toxicity

  Irene Riera-Tur, Tillman Schäfer, Daniel Hornburg, Archana Mishra, Miguel da Silva Padilha, Lorena Fernández-Mosquera, Dennis Feigenbutz, Patrick Auer, Matthias Mann, Wolfgang Baumeister, Rüdiger Klein, Felix Meissner, Nuno Raimundo, Rubén Fernández-Busnadiego, Irina Dudanova

  Irene Riera-Tur ... Irina Dudanova

  Published 21 December 2021
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  Open Access

  Poly(ADP-ribosyl)ating pathway regulates development from stem cell niche to longevity control

  Guillaume Bordet, Elena Kotova, Alexei V Tulin

  Guillaume Bordet ... Alexei V Tulin

  Published 23 December 2021
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  Open Access

  ADAR1 RNA editing regulates endothelial cell functions via the MDA-5 RNA sensing signaling pathway

  Xinfeng Guo, Silvia Liu, Rose Yan, Vy Nguyen, Mazen Zenati, Timothy R Billiar, Qingde Wang

  Xinfeng Guo ... Qingde Wang

  Published 30 December 2021
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  Open Access

  Electron cryo-tomography structure of axonemal doublet microtubule from Tetrahymena thermophila

  Sam Li, Jose-Jesus Fernandez, Amy S Fabritius, David A Agard, Mark Winey

  Sam Li ... Mark Winey

  Published 30 December 2021
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  Open Access

  Necrotic debris and STING exert therapeutically relevant effects on tumor cholesterol homeostasis

  Sampath Katakam, Santosh Anand, Patricia Martin, Nicolo Riggi, Ivan Stamenkovic

  Sampath Katakam ... Ivan Stamenkovic

  Published 4 January 2022
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  Open Access

  CNVs with adaptive potential in Rangifer tarandus: genome architecture and new annotated assembly

  Julien Prunier, Alexandra Carrier, Isabelle Gilbert, William Poisson, Vicky Albert, Joëlle Taillon, Vincent Bourret, Steeve D Côté, Arnaud Droit, Claude Robert

  Julien Prunier ... Claude Robert

  Published 15 December 2021
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  Open Access

  Loss of Nup210 results in muscle repair delays and age-associated alterations in muscle integrity

  Stephen Sakuma, Ethan YS Zhu, Marcela Raices, Pan Zhang, Rabi Murad, Maximiliano A D’Angelo

  Stephen Sakuma ... Maximiliano A D’Angelo

  Published 15 December 2021