Resolution of the curse of dimensionality in single-cell RNA sequencing data analysis

Yusuke Imoto; Tomonori Nakamura; Emerson G Escolar; Michio Yoshiwaki; Yoji Kojima; Yukihiro Yabuta; Yoshitaka Katou; Takuya Yamamoto; Yasuaki Hiraoka; Mitinori Saitou

doi:10.26508/lsa.202201591

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Resolution of the curse of dimensionality in single-cell RNA sequencing data analysis

View ORCID ProfileYusuke Imoto, View ORCID ProfileTomonori Nakamura, Emerson G Escolar, View ORCID ProfileMichio Yoshiwaki, Yoji Kojima, Yukihiro Yabuta, Yoshitaka Katou, View ORCID ProfileTakuya Yamamoto, View ORCID ProfileYasuaki Hiraoka Correspondence email, View ORCID ProfileMitinori Saitou Correspondence email

Yusuke Imoto

1Institute for the Advanced Study of Human Biology, Kyoto University Institute for Advanced Study, Kyoto University, Kyoto, Japan

Roles: Conceptualization, Data curation, Software, Formal analysis, Funding acquisition, Validation, Investigation, Visualization, Methodology, Writing—original draft, review, and editing, Code implementation

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ORCID record for Yusuke Imoto

Tomonori Nakamura

1Institute for the Advanced Study of Human Biology, Kyoto University Institute for Advanced Study, Kyoto University, Kyoto, Japan

2Department of Anatomy and Cell Biology, Graduate School of Medicine, Kyoto University, Kyoto, Japan

3The Hakubi Center for Advanced Research, Kyoto University, Kyoto, Japan

Roles: Conceptualization, Data curation, Formal analysis, Funding acquisition, Validation, Investigation, Visualization, Methodology, Writing—original draft, review, and editing

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ORCID record for Tomonori Nakamura

Emerson G Escolar

4Graduate School of Human Development and Environment, Kobe University, Kobe, Japan

5Center for Advanced Intelligence Project, RIKEN, Tokyo, Japan

Roles: Investigation and writing—original draft, review, and editing

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Michio Yoshiwaki

5Center for Advanced Intelligence Project, RIKEN, Tokyo, Japan

Roles: Investigation and writing—original draft, review, and editing

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ORCID record for Michio Yoshiwaki

Yoji Kojima

1Institute for the Advanced Study of Human Biology, Kyoto University Institute for Advanced Study, Kyoto University, Kyoto, Japan

2Department of Anatomy and Cell Biology, Graduate School of Medicine, Kyoto University, Kyoto, Japan

6Center for iPS Cell Research and Application, Kyoto University, Kyoto, Japan

Roles: Data curation and investigation

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Yukihiro Yabuta

1Institute for the Advanced Study of Human Biology, Kyoto University Institute for Advanced Study, Kyoto University, Kyoto, Japan

2Department of Anatomy and Cell Biology, Graduate School of Medicine, Kyoto University, Kyoto, Japan

Roles: Investigation

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Yoshitaka Katou

2Department of Anatomy and Cell Biology, Graduate School of Medicine, Kyoto University, Kyoto, Japan

Roles: Investigation and code implementation

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Takuya Yamamoto

1Institute for the Advanced Study of Human Biology, Kyoto University Institute for Advanced Study, Kyoto University, Kyoto, Japan

5Center for Advanced Intelligence Project, RIKEN, Tokyo, Japan

6Center for iPS Cell Research and Application, Kyoto University, Kyoto, Japan

Roles: Conceptualization

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ORCID record for Takuya Yamamoto

Yasuaki Hiraoka

1Institute for the Advanced Study of Human Biology, Kyoto University Institute for Advanced Study, Kyoto University, Kyoto, Japan

5Center for Advanced Intelligence Project, RIKEN, Tokyo, Japan

7Center for Advanced Study, Kyoto University Institute for Advanced Study, Kyoto University, Kyoto, Japan

Roles: Conceptualization, Supervision, Funding acquisition, Investigation, Project administration, Writing—original draft, review, and editing

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ORCID record for Yasuaki Hiraoka
For correspondence: hiraoka.yasuaki.6z@kyoto-u.ac.jp saitou@anat2.med.kyoto-u.ac.jp

Mitinori Saitou

1Institute for the Advanced Study of Human Biology, Kyoto University Institute for Advanced Study, Kyoto University, Kyoto, Japan

2Department of Anatomy and Cell Biology, Graduate School of Medicine, Kyoto University, Kyoto, Japan

6Center for iPS Cell Research and Application, Kyoto University, Kyoto, Japan

Roles: Conceptualization, Supervision, Funding acquisition, Project administration, Writing—original draft, review, and editing

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ORCID record for Mitinori Saitou
For correspondence: hiraoka.yasuaki.6z@kyoto-u.ac.jp saitou@anat2.med.kyoto-u.ac.jp

Published 9 August 2022. DOI: 10.26508/lsa.202201591

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RECODE for scRNA-seq data

Yusuke Imoto, Tomonori Nakamura, Emerson G Escolar, Michio Yoshiwaki, Yoji Kojima, Yukihiro Yabuta, Yoshitaka Katou, Takuya Yamamoto, Yasuaki Hiraoka, Mitinori Saitou

Life Science Alliance Aug 2022, 5 (12) e202201591; DOI: 10.26508/lsa.202201591

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RECODE for scRNA-seq data

Yusuke Imoto, Tomonori Nakamura, Emerson G Escolar, Michio Yoshiwaki, Yoji Kojima, Yukihiro Yabuta, Yoshitaka Katou, Takuya Yamamoto, Yasuaki Hiraoka, Mitinori Saitou

Life Science Alliance Aug 2022, 5 (12) e202201591; DOI: 10.26508/lsa.202201591

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