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Research Article
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Whole-exome sequencing of epithelial ovarian carcinomas differing in resistance to platinum therapy

View ORCID ProfileViktor Hlaváč, View ORCID ProfilePetr Holý, Radka Václavíková, View ORCID ProfileLukáš Rob, Martin Hruda, Marcela Mrhalová, Petr Černaj, Jiří Bouda, View ORCID ProfilePavel Souček  Correspondence email
Viktor Hlaváč
1Biomedical Center, Faculty of Medicine in Pilsen, Charles University, Pilsen, Czech Republic
2Toxicogenomics Unit, National Institute of Public Health, Prague, Czech Republic
Roles: Conceptualization, Investigation, Methodology, Writing—original draft, Writing—review and editing
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  • ORCID record for Viktor Hlaváč
Petr Holý
1Biomedical Center, Faculty of Medicine in Pilsen, Charles University, Pilsen, Czech Republic
2Toxicogenomics Unit, National Institute of Public Health, Prague, Czech Republic
3Third Faculty of Medicine, Charles University, Prague, Czech Republic
Roles: Formal analysis, Investigation, Methodology, Writing—original draft, Writing—review and editing
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  • ORCID record for Petr Holý
Radka Václavíková
1Biomedical Center, Faculty of Medicine in Pilsen, Charles University, Pilsen, Czech Republic
2Toxicogenomics Unit, National Institute of Public Health, Prague, Czech Republic
Roles: Data curation, Formal analysis, Writing—review and editing
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Lukáš Rob
4Department of Gynecology and Obstetrics, Third Faculty of Medicine, Charles University and University Hospital Královské Vinohrady, Prague, Czech Republic
Roles: Resources, Data curation, Writing—review and editing
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  • ORCID record for Lukáš Rob
Martin Hruda
4Department of Gynecology and Obstetrics, Third Faculty of Medicine, Charles University and University Hospital Královské Vinohrady, Prague, Czech Republic
Roles: Resources, Data curation, Writing—review and editing
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Marcela Mrhalová
5Department of Pathology and Molecular Medicine, Second Faculty of Medicine and Motol University Hospital, Charles University, Prague, Czech Republic
Roles: Data curation, Formal analysis, Writing—review and editing
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Petr Černaj
6Department of Gynecology and Obstetrics, Faculty of Medicine and University Hospital in Pilsen, Charles University, Pilsen, Czech Republic
Roles: Resources, Data curation, Writing—review and editing
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Jiří Bouda
6Department of Gynecology and Obstetrics, Faculty of Medicine and University Hospital in Pilsen, Charles University, Pilsen, Czech Republic
Roles: Resources, Data curation, Writing—review and editing
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Pavel Souček
1Biomedical Center, Faculty of Medicine in Pilsen, Charles University, Pilsen, Czech Republic
2Toxicogenomics Unit, National Institute of Public Health, Prague, Czech Republic
Roles: Conceptualization, Formal analysis, Supervision, Funding acquisition, Writing—original draft, review, and editing
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  • For correspondence: pavel.soucek@szu.cz
Published 13 October 2022. DOI: 10.26508/lsa.202201551
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Article Information

vol. 5 no. 12 e202201551
DOI 
https://doi.org/10.26508/lsa.202201551
PubMed 
36229065

Published By 
Life Science Alliance
Online ISSN 
2575-1077
History 
  • Received June 7, 2022
  • Revision received September 23, 2022
  • Accepted September 23, 2022
  • Published online October 13, 2022.

Copyright & Usage 
© 2022 Hlaváč et al. This article is available under a Creative Commons License (Attribution 4.0 International, as described at https://creativecommons.org/licenses/by/4.0/).

Author Information

  1. Viktor Hlaváč1,2, Conceptualization, Investigation, Methodology, Writing—original draft, Writing—review and editing,
  2. Petr Holý1,2,3, Formal analysis, Investigation, Methodology, Writing—original draft, Writing—review and editing,
  3. Radka Václavíková1,2, Data curation, Formal analysis, Writing—review and editing,
  4. Lukáš Rob4, Resources, Data curation, Writing—review and editing,
  5. Martin Hruda4, Resources, Data curation, Writing—review and editing,
  6. Marcela Mrhalová5, Data curation, Formal analysis, Writing—review and editing,
  7. Petr Černaj6, Resources, Data curation, Writing—review and editing,
  8. Jiří Bouda6, Resources, Data curation, Writing—review and editing and
  9. Pavel Souček1,2, Conceptualization, Formal analysis, Supervision, Funding acquisition, Writing—original draft, review, and editing⇑
  1. 1Biomedical Center, Faculty of Medicine in Pilsen, Charles University, Pilsen, Czech Republic
  2. 2Toxicogenomics Unit, National Institute of Public Health, Prague, Czech Republic
  3. 3Third Faculty of Medicine, Charles University, Prague, Czech Republic
  4. 4Department of Gynecology and Obstetrics, Third Faculty of Medicine, Charles University and University Hospital Královské Vinohrady, Prague, Czech Republic
  5. 5Department of Pathology and Molecular Medicine, Second Faculty of Medicine and Motol University Hospital, Charles University, Prague, Czech Republic
  6. 6Department of Gynecology and Obstetrics, Faculty of Medicine and University Hospital in Pilsen, Charles University, Pilsen, Czech Republic
  1. Correspondence: pavel.soucek{at}szu.cz
View Full Text

Funding

  • Czech Health Research Council

    NV19-08-00113
    P Souček
  • Cooperatio Program

    207035
    L Rob
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Exome profile of resistant epithelial ovarian carcinoma
Viktor Hlaváč, Petr Holý, Radka Václavíková, Lukáš Rob, Martin Hruda, Marcela Mrhalová, Petr Černaj, Jiří Bouda, Pavel Souček
Life Science Alliance Oct 2022, 5 (12) e202201551; DOI: 10.26508/lsa.202201551

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Exome profile of resistant epithelial ovarian carcinoma
Viktor Hlaváč, Petr Holý, Radka Václavíková, Lukáš Rob, Martin Hruda, Marcela Mrhalová, Petr Černaj, Jiří Bouda, Pavel Souček
Life Science Alliance Oct 2022, 5 (12) e202201551; DOI: 10.26508/lsa.202201551
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Volume 5, No. 12
December 2022
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