ERK-Smurf1-RhoA signaling is critical for TGFβ-drived EMT and tumor metastasis

Jianzhong Zheng; Zhiyuan Shi; Pengbo Yang; Yue Zhao; Wenbin Tang; Shaopei Ye; Zuodong Xuan; Chen Chen; Chen Shao; Qingang Wu; Huimin Sun

doi:10.26508/lsa.202101330

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ERK-Smurf1-RhoA signaling is critical for TGFβ-drived EMT and tumor metastasis

View ORCID ProfileJianzhong Zheng, Zhiyuan Shi, Pengbo Yang, Yue Zhao, View ORCID ProfileWenbin Tang, Shaopei Ye, Zuodong Xuan, Chen Chen, Chen Shao, View ORCID ProfileQingang Wu Correspondence email, Huimin Sun Correspondence email

Jianzhong Zheng

1School of Medicine, Xiamen University, Xiamen, China

2Department of Urology, Xiang’an Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, China

Roles: Conceptualization, Data curation, Software, Formal analysis, Funding acquisition, Investigation, Methodology

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ORCID record for Jianzhong Zheng

Zhiyuan Shi

1School of Medicine, Xiamen University, Xiamen, China

2Department of Urology, Xiang’an Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, China

Roles: Data curation, Software, Formal analysis

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Pengbo Yang

6Key Laboratory of Birth Defects and Related Diseases of Women and Children of MOE, State Key Laboratory of Biotherapy, West China Second University Hospital, Sichuan University, Chengdu, China

Roles: Resources and software

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Yue Zhao

1School of Medicine, Xiamen University, Xiamen, China

2Department of Urology, Xiang’an Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, China

Roles: Software, Resources, Data curation

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Wenbin Tang

1School of Medicine, Xiamen University, Xiamen, China

2Department of Urology, Xiang’an Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, China

Roles: Resources

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ORCID record for Wenbin Tang

Shaopei Ye

1School of Medicine, Xiamen University, Xiamen, China

2Department of Urology, Xiang’an Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, China

Roles: Resources

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Zuodong Xuan

1School of Medicine, Xiamen University, Xiamen, China

2Department of Urology, Xiang’an Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, China

Roles: Software and formal analysis

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Chen Chen

1School of Medicine, Xiamen University, Xiamen, China

2Department of Urology, Xiang’an Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, China

Roles: Software and methodology

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Chen Shao

2Department of Urology, Xiang’an Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, China

Roles: Supervision, Funding acquisition, Project administration, Writing—original draft, review, and editing

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Qingang Wu

1School of Medicine, Xiamen University, Xiamen, China

3Zhejiang Provincial Key Laboratory of Pancreatic Disease, The First Affiliated Hospital, and Institute of Translational Medicine, Zhejiang University School of Medicine, Hangzhou, China

Roles: Supervision, Project administration, Writing—original draft, review, and editing

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ORCID record for Qingang Wu
For correspondence: hmsun@xah.xmu.edu.cn Qingangwu@126.com

Huimin Sun

4The Central Lab of Xiang’an Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, China

5The Key Laboratory for Endocrine Related Cancer Precision Medicine Of Xiamen, Xiang'an Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, China

Roles: Supervision, Funding acquisition, Writing—original draft

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For correspondence: hmsun@xah.xmu.edu.cn Qingangwu@126.com

Published 2 June 2022. DOI: 10.26508/lsa.202101330

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Role of ERK-Smurf1-RhoA axis in EMT

Jianzhong Zheng, Zhiyuan Shi, Pengbo Yang, Yue Zhao, Wenbin Tang, Shaopei Ye, Zuodong Xuan, Chen Chen, Chen Shao, Qingang Wu, Huimin Sun

Life Science Alliance Jun 2022, 5 (10) e202101330; DOI: 10.26508/lsa.202101330

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Role of ERK-Smurf1-RhoA axis in EMT

Jianzhong Zheng, Zhiyuan Shi, Pengbo Yang, Yue Zhao, Wenbin Tang, Shaopei Ye, Zuodong Xuan, Chen Chen, Chen Shao, Qingang Wu, Huimin Sun

Life Science Alliance Jun 2022, 5 (10) e202101330; DOI: 10.26508/lsa.202101330

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