PROSER1 mediates TET2 O-GlcNAcylation to regulate DNA demethylation on UTX-dependent enhancers and CpG islands

Xiaokang Wang; Wojciech Rosikiewicz; Yurii Sedkov; Tanner Martinez; Baranda S Hansen; Patrick Schreiner; Jesper Christensen; Beisi Xu; Shondra M Pruett-Miller; Kristian Helin; Hans-Martin Herz

doi:10.26508/lsa.202101228

Research Article

Open Access

PROSER1 mediates TET2 O-GlcNAcylation to regulate DNA demethylation on UTX-dependent enhancers and CpG islands

View ORCID ProfileXiaokang Wang, View ORCID ProfileWojciech Rosikiewicz, Yurii Sedkov, View ORCID ProfileTanner Martinez, Baranda S Hansen, Patrick Schreiner, Jesper Christensen, Beisi Xu, View ORCID ProfileShondra M Pruett-Miller, View ORCID ProfileKristian Helin, View ORCID ProfileHans-Martin Herz Correspondence email

Xiaokang Wang

1Department of Cell and Molecular Biology, St. Jude Children’s Research Hospital, Memphis, TN, USA

Roles: Conceptualization, Data curation, Formal analysis, Validation, Investigation, Visualization, Methodology, Project administration, Writing—original draft, review, and editing

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
ORCID record for Xiaokang Wang

Wojciech Rosikiewicz

2Center for Applied Bioinformatics, St. Jude Children’s Research Hospital, Memphis, TN, USA

Roles: Data curation, Software, Formal analysis, Investigation, Visualization, Methodology, Writing—review and editing

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
ORCID record for Wojciech Rosikiewicz

Yurii Sedkov

1Department of Cell and Molecular Biology, St. Jude Children’s Research Hospital, Memphis, TN, USA

Roles: Data curation, Formal analysis, Validation, Investigation, Visualization, Methodology

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Tanner Martinez

1Department of Cell and Molecular Biology, St. Jude Children’s Research Hospital, Memphis, TN, USA

Roles: Data curation, Formal analysis, Validation, Investigation, Methodology

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
ORCID record for Tanner Martinez

Baranda S Hansen

1Department of Cell and Molecular Biology, St. Jude Children’s Research Hospital, Memphis, TN, USA

Roles: Resources, Data curation, Formal analysis, Validation, Investigation, Visualization, Methodology

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Patrick Schreiner

2Center for Applied Bioinformatics, St. Jude Children’s Research Hospital, Memphis, TN, USA

Roles: Data curation, Software, Formal analysis, Validation, Visualization, Methodology

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Jesper Christensen

3Biotech Research and Innovation Centre and The Novo Nordisk Foundation for Stem Cell Biology, University of Copenhagen, Copenhagen, Denmark

Roles: Resources

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Beisi Xu

2Center for Applied Bioinformatics, St. Jude Children’s Research Hospital, Memphis, TN, USA

Roles: Data curation, Software, Formal analysis, Visualization, Methodology

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Shondra M Pruett-Miller

1Department of Cell and Molecular Biology, St. Jude Children’s Research Hospital, Memphis, TN, USA

Roles: Resources, Data curation, Formal analysis, Supervision, Funding acquisition, Validation, Investigation, Visualization, Methodology, Project administration

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
ORCID record for Shondra M Pruett-Miller

Kristian Helin

3Biotech Research and Innovation Centre and The Novo Nordisk Foundation for Stem Cell Biology, University of Copenhagen, Copenhagen, Denmark

4Cell Biology Program and Center for Epigenetics Research, Memorial Sloan Kettering Cancer Center, New York City, New York, USA

Roles: Resources, Funding acquisition

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
ORCID record for Kristian Helin

Hans-Martin Herz

1Department of Cell and Molecular Biology, St. Jude Children’s Research Hospital, Memphis, TN, USA

Roles: Conceptualization, Resources, Data curation, Formal analysis, Supervision, Funding acquisition, Validation, Investigation, Visualization, Methodology, Project administration, Writing—original draft, review, and editing

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
ORCID record for Hans-Martin Herz
For correspondence: hans-martin.herz@stjude.org

Published 19 October 2021. DOI: 10.26508/lsa.202101228

Article
Figures & Data
Info
Metrics
Reviewer Comments
PDF

You are using an old browser, click here to download PDF

PDF Container

PreviousNext

Download PDF

Email Article

Thank you for your interest in spreading the word on Life Science Alliance.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Your Email *

Your Name *

Send To *

Enter multiple addresses on separate lines or separate them with commas.

You are going to email the following PROSER1 mediates TET2 O-GlcNAcylation to regulate DNA demethylation on UTX-dependent enhancers and CpG islands

Message Subject (Your Name) has sent you a message from Life Science Alliance

Message Body (Your Name) thought you would like to see the Life Science Alliance web site.

Your Personal Message

CAPTCHA

This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.

Citation Tools

PROSER1 regulates DNA demethylation

Xiaokang Wang, Wojciech Rosikiewicz, Yurii Sedkov, Tanner Martinez, Baranda S Hansen, Patrick Schreiner, Jesper Christensen, Beisi Xu, Shondra M Pruett-Miller, Kristian Helin, Hans-Martin Herz

Life Science Alliance Oct 2021, 5 (1) e202101228; DOI: 10.26508/lsa.202101228

Citation Manager Formats

BibTeX
Bookends
EasyBib
EndNote (tagged)
EndNote 8 (xml)
Medlars
Mendeley
Papers
RefWorks Tagged
Ref Manager
RIS
Zotero

PROSER1 regulates DNA demethylation

Xiaokang Wang, Wojciech Rosikiewicz, Yurii Sedkov, Tanner Martinez, Baranda S Hansen, Patrick Schreiner, Jesper Christensen, Beisi Xu, Shondra M Pruett-Miller, Kristian Helin, Hans-Martin Herz

Life Science Alliance Oct 2021, 5 (1) e202101228; DOI: 10.26508/lsa.202101228

Share This Article:

Tweet Widget

In this Issue

Volume 5, No. 1

January 2022

Table of Contents
Cover (PDF)
About the Cover
Masthead (PDF)

Jump to section

Article
Figures & Data
Info
Metrics
Reviewer Comments
PDF

Subjects

Chromatin & Epigenetics
Molecular Biology

No related articles found.

Cited By...

OGT prevents DNA demethylation and suppresses the expression of transposable elements in heterochromatin by restraining TET activity genome-wide
Neuron-specific chromatin disruption at CpG islands and aging-related regions in Kabuki syndrome mice

Google Scholar

Main menu

User menu

Search

PROSER1 mediates TET2 O-GlcNAcylation to regulate DNA demethylation on UTX-dependent enhancers and CpG islands

Citation Manager Formats

In this Issue

Subjects

Related Articles

Cited By...

More in this TOC Section

Similar Articles

Content

For Authors

Other Services

More Information