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Research Article
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Heterogeneous nuclear ribonucleoprotein E1 binds polycytosine DNA and monitors genome integrity

Bidyut K Mohanty, View ORCID ProfileJoseph AQ Karam, Breege V Howley, Annamarie C Dalton, Simon Grelet, View ORCID ProfileToros Dincman, View ORCID ProfileWilliam S Streitfeld, Je-Hyun Yoon, Lata Balakrishnan, View ORCID ProfileWalter J Chazin, View ORCID ProfileDavid T Long, View ORCID ProfilePhilip H Howe  Correspondence email
Bidyut K Mohanty
1Department of Biochemistry and Molecular Biology, Medical University of South Carolina, Charleston, SC, USA
Roles: Conceptualization, Formal analysis, Investigation, Methodology, Writing—original draft
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Joseph AQ Karam
1Department of Biochemistry and Molecular Biology, Medical University of South Carolina, Charleston, SC, USA
Roles: Conceptualization, Formal analysis, Validation, Investigation, Methodology, Writing—review and editing
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  • ORCID record for Joseph AQ Karam
Breege V Howley
1Department of Biochemistry and Molecular Biology, Medical University of South Carolina, Charleston, SC, USA
Roles: Conceptualization, Investigation, Writing—review and editing
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Annamarie C Dalton
1Department of Biochemistry and Molecular Biology, Medical University of South Carolina, Charleston, SC, USA
Roles: Investigation, Writing—review and editing
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Simon Grelet
1Department of Biochemistry and Molecular Biology, Medical University of South Carolina, Charleston, SC, USA
2Hollings Cancer Center, Medical University of South Carolina, Charleston, SC, USA
Roles: Formal analysis, Investigation, Methodology
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Toros Dincman
3Division of Hematology and Oncology, Department of Medicine, Medical University of South Carolina, Charleston, SC, USA
Roles: Investigation
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  • ORCID record for Toros Dincman
William S Streitfeld
1Department of Biochemistry and Molecular Biology, Medical University of South Carolina, Charleston, SC, USA
Roles: Investigation
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  • ORCID record for William S Streitfeld
Je-Hyun Yoon
1Department of Biochemistry and Molecular Biology, Medical University of South Carolina, Charleston, SC, USA
Roles: Investigation
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Lata Balakrishnan
4Department of Biology, School of Science, Indiana University Purdue University Indianapolis, Indianapolis, IN, USA
Roles: Resources
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Walter J Chazin
5Departments of Biochemistry and Chemistry and Center for Structural Biology, Vanderbilt University, Nashville, TN, USA
Roles: Resources
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  • ORCID record for Walter J Chazin
David T Long
1Department of Biochemistry and Molecular Biology, Medical University of South Carolina, Charleston, SC, USA
Roles: Resources, Writing—original draft, review, and editing
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  • ORCID record for David T Long
Philip H Howe
1Department of Biochemistry and Molecular Biology, Medical University of South Carolina, Charleston, SC, USA
2Hollings Cancer Center, Medical University of South Carolina, Charleston, SC, USA
Roles: Conceptualization, Resources, Supervision, Funding acquisition, Writing—review and editing
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  • For correspondence: howep@musc.edu
Published 16 July 2021. DOI: 10.26508/lsa.202000995
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hnRNP E1 binds polycytosine DNA tracts
Bidyut K Mohanty, Joseph AQ Karam, Breege V Howley, Annamarie C Dalton, Simon Grelet, Toros Dincman, William S Streitfeld, Je-Hyun Yoon, Lata Balakrishnan, Walter J Chazin, David T Long, Philip H Howe
Life Science Alliance Jul 2021, 4 (9) e202000995; DOI: 10.26508/lsa.202000995

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hnRNP E1 binds polycytosine DNA tracts
Bidyut K Mohanty, Joseph AQ Karam, Breege V Howley, Annamarie C Dalton, Simon Grelet, Toros Dincman, William S Streitfeld, Je-Hyun Yoon, Lata Balakrishnan, Walter J Chazin, David T Long, Philip H Howe
Life Science Alliance Jul 2021, 4 (9) e202000995; DOI: 10.26508/lsa.202000995
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Volume 4, No. 9
September 2021
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