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Exosome-mediated delivery of CRISPR/Cas9 for targeting of oncogenic KrasG12D in pancreatic cancer

View ORCID ProfileKathleen M McAndrews, Fei Xiao, Antonios Chronopoulos, Valerie S LeBleu, Fernanda G Kugeratski, View ORCID ProfileRaghu Kalluri  Correspondence email
Kathleen M McAndrews
1Department of Cancer Biology, Metastasis Research Center, University of Texas MD Anderson Cancer Center, Houston, TX, USA
Roles: Data curation, Formal analysis, Investigation, Visualization, Writing—original draft, review, and editing
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  • ORCID record for Kathleen M McAndrews
Fei Xiao
1Department of Cancer Biology, Metastasis Research Center, University of Texas MD Anderson Cancer Center, Houston, TX, USA
Roles: Data curation, Formal analysis, Investigation, Methodology
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Antonios Chronopoulos
1Department of Cancer Biology, Metastasis Research Center, University of Texas MD Anderson Cancer Center, Houston, TX, USA
Roles: Data curation, Visualization, Writing—original draft, review, and editing
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Valerie S LeBleu
1Department of Cancer Biology, Metastasis Research Center, University of Texas MD Anderson Cancer Center, Houston, TX, USA
4Feinberg School of Medicine, Northwestern University, Chicago, IL, USA
Roles: Supervision, Investigation, Project administration
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Fernanda G Kugeratski
1Department of Cancer Biology, Metastasis Research Center, University of Texas MD Anderson Cancer Center, Houston, TX, USA
Roles: Data curation, Investigation, Visualization, Writing—review and editing
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Raghu Kalluri
1Department of Cancer Biology, Metastasis Research Center, University of Texas MD Anderson Cancer Center, Houston, TX, USA
2Department of Bioengineering, Rice University, Houston, TX, USA
3Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX, USA
Roles: Conceptualization, Supervision, Funding acquisition, Writing—original draft, review, and editing
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  • ORCID record for Raghu Kalluri
  • For correspondence: rkalluri@mdanderson.org
Published 19 July 2021. DOI: 10.26508/lsa.202000875
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Exosomes for CRISPR targeting of oncogenic KrasG12D mutation
Kathleen M McAndrews, Fei Xiao, Antonios Chronopoulos, Valerie S LeBleu, Fernanda G Kugeratski, Raghu Kalluri
Life Science Alliance Jul 2021, 4 (9) e202000875; DOI: 10.26508/lsa.202000875

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Exosomes for CRISPR targeting of oncogenic KrasG12D mutation
Kathleen M McAndrews, Fei Xiao, Antonios Chronopoulos, Valerie S LeBleu, Fernanda G Kugeratski, Raghu Kalluri
Life Science Alliance Jul 2021, 4 (9) e202000875; DOI: 10.26508/lsa.202000875
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Volume 4, No. 9
September 2021
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  • Cancer
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