Crystal structure of inhibitor-bound human MSPL that can activate high pathogenic avian influenza

Ayako Ohno; Nobuo Maita; Takanori Tabata; Hikaru Nagano; Kyohei Arita; Mariko Ariyoshi; Takayuki Uchida; Reiko Nakao; Anayt Ulla; Kosuke Sugiura; Koji Kishimoto; Shigetada Teshima-Kondo; Yuushi Okumura; Takeshi Nikawa

doi:10.26508/lsa.202000849

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Crystal structure of inhibitor-bound human MSPL that can activate high pathogenic avian influenza

Ayako Ohno, View ORCID ProfileNobuo Maita, Takanori Tabata, View ORCID ProfileHikaru Nagano, Kyohei Arita, View ORCID ProfileMariko Ariyoshi, Takayuki Uchida, Reiko Nakao, View ORCID ProfileAnayt Ulla, Kosuke Sugiura, Koji Kishimoto, Shigetada Teshima-Kondo, View ORCID ProfileYuushi Okumura Correspondence email, Takeshi Nikawa

Ayako Ohno

1Department of Nutritional Physiology, Institute of Medical Nutrition, Tokushima University Graduate School, Tokushima, Japan

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Nobuo Maita

2Division of Disease Proteomics, Institute of Advanced Medical Sciences, Tokushima University, Tokushima, Japan

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Takanori Tabata

3Laboratory for Pharmacology, Pharmaceutical Research Center, Asahikasei Pharma, Shizuoka, Japan

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Hikaru Nagano

4Department of Nutrition, Graduate School of Comprehensive Rehabilitation, Osaka Prefecture University, Osaka, Japan

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Kyohei Arita

5Graduate School of Medical Life Science, Yokohama City University, Kanagawa, Japan

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Mariko Ariyoshi

6Graduate School of Frontier Biosciences, Osaka University, Osaka, Japan

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Takayuki Uchida

1Department of Nutritional Physiology, Institute of Medical Nutrition, Tokushima University Graduate School, Tokushima, Japan

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Reiko Nakao

1Department of Nutritional Physiology, Institute of Medical Nutrition, Tokushima University Graduate School, Tokushima, Japan

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Anayt Ulla

1Department of Nutritional Physiology, Institute of Medical Nutrition, Tokushima University Graduate School, Tokushima, Japan

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Kosuke Sugiura

1Department of Nutritional Physiology, Institute of Medical Nutrition, Tokushima University Graduate School, Tokushima, Japan

7Department of Orthopedics, Institute of Biomedical Sciences, Tokushima University Graduate School, Tokushima, Japan

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Koji Kishimoto

8Graduate School of Technology, Industrial and Social Sciences, Tokushima University, Tokushima, Japan

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Shigetada Teshima-Kondo

4Department of Nutrition, Graduate School of Comprehensive Rehabilitation, Osaka Prefecture University, Osaka, Japan

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Yuushi Okumura

9Department of Nutrition and Health, Faculty of Nutritional Science, Sagami Women’s University, Kanagawa, Japan

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For correspondence: okumura_yushi@isc.sagami-wu.ac.jp

Takeshi Nikawa

1Department of Nutritional Physiology, Institute of Medical Nutrition, Tokushima University Graduate School, Tokushima, Japan

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Published 5 April 2021. DOI: 10.26508/lsa.202000849

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Structure of MSPL–inhibitor complex

Ayako Ohno, Nobuo Maita, Takanori Tabata, Hikaru Nagano, Kyohei Arita, Mariko Ariyoshi, Takayuki Uchida, Reiko Nakao, Anayt Ulla, Kosuke Sugiura, Koji Kishimoto, Shigetada Teshima-Kondo, Yuushi Okumura, Takeshi Nikawa

Life Science Alliance Apr 2021, 4 (6) e202000849; DOI: 10.26508/lsa.202000849

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Structure of MSPL–inhibitor complex

Life Science Alliance Apr 2021, 4 (6) e202000849; DOI: 10.26508/lsa.202000849

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