Kalirin-RAC controls nucleokinetic migration in ADRN-type neuroblastoma

Elena A Afanasyeva; Moritz Gartlgruber; Tatsiana Ryl; Bieke Decaesteker; Geertrui Denecker; Gregor Mönke; Umut H Toprak; Andres Florez; Alica Torkov; Daniel Dreidax; Carl Herrmann; Konstantin Okonechnikov; Sara Ek; Ashwini Kumar Sharma; Vitaliya Sagulenko; Frank Speleman; Kai-Oliver Henrich; Frank Westermann

doi:10.26508/lsa.201900332

Research Article

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Kalirin-RAC controls nucleokinetic migration in ADRN-type neuroblastoma

View ORCID ProfileElena A Afanasyeva Correspondence email, Moritz Gartlgruber, Tatsiana Ryl, View ORCID ProfileBieke Decaesteker, Geertrui Denecker, Gregor Mönke, Umut H Toprak, View ORCID ProfileAndres Florez, Alica Torkov, Daniel Dreidax, Carl Herrmann, Konstantin Okonechnikov, Sara Ek, Ashwini Kumar Sharma, View ORCID ProfileVitaliya Sagulenko, Frank Speleman, Kai-Oliver Henrich, View ORCID ProfileFrank Westermann Correspondence email

Elena A Afanasyeva

1Department of Neuroblastoma Genomics, Hopp-Children’s Cancer Center at the (NCT) Nationales Centrum für Tumorerkrankungen Heidelberg (KiTZ), Heidelberg, Germany

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ORCID record for Elena A Afanasyeva
For correspondence: elena.afanasyeva@alumni.dkfz.de

Moritz Gartlgruber

1Department of Neuroblastoma Genomics, Hopp-Children’s Cancer Center at the (NCT) Nationales Centrum für Tumorerkrankungen Heidelberg (KiTZ), Heidelberg, Germany

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Tatsiana Ryl

2Department of Neurosurgery, University of Duisburg Essen, Essen, Germany

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Bieke Decaesteker

3Center for Medical Genetics, Ghent University, and Cancer Research Institute Ghent, Ghent, Belgium

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ORCID record for Bieke Decaesteker

Geertrui Denecker

3Center for Medical Genetics, Ghent University, and Cancer Research Institute Ghent, Ghent, Belgium

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Gregor Mönke

4European Molecular Biology Laboratories, Heidelberg, Germany

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Umut H Toprak

1Department of Neuroblastoma Genomics, Hopp-Children’s Cancer Center at the (NCT) Nationales Centrum für Tumorerkrankungen Heidelberg (KiTZ), Heidelberg, Germany

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Andres Florez

1Department of Neuroblastoma Genomics, Hopp-Children’s Cancer Center at the (NCT) Nationales Centrum für Tumorerkrankungen Heidelberg (KiTZ), Heidelberg, Germany

5Center for Systems Biology, Faculty of Arts and Sciences, Harvard University, Cambridge, MA, USA

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Alica Torkov

1Department of Neuroblastoma Genomics, Hopp-Children’s Cancer Center at the (NCT) Nationales Centrum für Tumorerkrankungen Heidelberg (KiTZ), Heidelberg, Germany

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Daniel Dreidax

1Department of Neuroblastoma Genomics, Hopp-Children’s Cancer Center at the (NCT) Nationales Centrum für Tumorerkrankungen Heidelberg (KiTZ), Heidelberg, Germany

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Carl Herrmann

6Group of Cancer Regulatory Genomics B086, German Cancer Research Center (DKFZ), Heidelberg, Germany

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Konstantin Okonechnikov

7Department of Pediatric Neurooncology, Hopp-Children’s Cancer Center at the (NCT) Nationales Centrum für Tumorerkrankungen Heidelberg (KiTZ), Heidelberg, Germany

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Sara Ek

8Department of Immunotechnology, CREATE Health, Faculty of Engineering, Lund University, Lund, Sweden

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Ashwini Kumar Sharma

9Institute for Pharmacy and Molecular Biotechnology and BioQuant, Heidelberg University, Heidelberg, Germany

10Division of Theoretical Bioinformatics, German Cancer Research Center (DKFZ), Heidelberg, Germany

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Vitaliya Sagulenko

11School of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, Australia

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Frank Speleman

3Center for Medical Genetics, Ghent University, and Cancer Research Institute Ghent, Ghent, Belgium

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Kai-Oliver Henrich

1Department of Neuroblastoma Genomics, Hopp-Children’s Cancer Center at the (NCT) Nationales Centrum für Tumorerkrankungen Heidelberg (KiTZ), Heidelberg, Germany

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Frank Westermann

1Department of Neuroblastoma Genomics, Hopp-Children’s Cancer Center at the (NCT) Nationales Centrum für Tumorerkrankungen Heidelberg (KiTZ), Heidelberg, Germany

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ORCID record for Frank Westermann
For correspondence: f.westermann@dkfz.de

Published 3 March 2021. DOI: 10.26508/lsa.201900332

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Kalirin suppression stops nucleokinetic migration

Elena A Afanasyeva, Moritz Gartlgruber, Tatsiana Ryl, Bieke Decaesteker, Geertrui Denecker, Gregor Mönke, Umut H Toprak, Andres Florez, Alica Torkov, Daniel Dreidax, Carl Herrmann, Konstantin Okonechnikov, Sara Ek, Ashwini Kumar Sharma, Vitaliya Sagulenko, Frank Speleman, Kai-Oliver Henrich, Frank Westermann

Life Science Alliance Mar 2021, 4 (5) e201900332; DOI: 10.26508/lsa.201900332

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Kalirin suppression stops nucleokinetic migration

Life Science Alliance Mar 2021, 4 (5) e201900332; DOI: 10.26508/lsa.201900332

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