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Research Article
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Kalirin-RAC controls nucleokinetic migration in ADRN-type neuroblastoma

View ORCID ProfileElena A Afanasyeva  Correspondence email, Moritz Gartlgruber, Tatsiana Ryl, View ORCID ProfileBieke Decaesteker, Geertrui Denecker, Gregor Mönke, Umut H Toprak, View ORCID ProfileAndres Florez, Alica Torkov, Daniel Dreidax, Carl Herrmann, Konstantin Okonechnikov, Sara Ek, Ashwini Kumar Sharma, View ORCID ProfileVitaliya Sagulenko, Frank Speleman, Kai-Oliver Henrich, View ORCID ProfileFrank Westermann  Correspondence email
Elena A Afanasyeva
1Department of Neuroblastoma Genomics, Hopp-Children’s Cancer Center at the (NCT) Nationales Centrum für Tumorerkrankungen Heidelberg (KiTZ), Heidelberg, Germany
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  • ORCID record for Elena A Afanasyeva
  • For correspondence: elena.afanasyeva@alumni.dkfz.de
Moritz Gartlgruber
1Department of Neuroblastoma Genomics, Hopp-Children’s Cancer Center at the (NCT) Nationales Centrum für Tumorerkrankungen Heidelberg (KiTZ), Heidelberg, Germany
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Tatsiana Ryl
2Department of Neurosurgery, University of Duisburg Essen, Essen, Germany
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Bieke Decaesteker
3Center for Medical Genetics, Ghent University, and Cancer Research Institute Ghent, Ghent, Belgium
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  • ORCID record for Bieke Decaesteker
Geertrui Denecker
3Center for Medical Genetics, Ghent University, and Cancer Research Institute Ghent, Ghent, Belgium
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Gregor Mönke
4European Molecular Biology Laboratories, Heidelberg, Germany
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Umut H Toprak
1Department of Neuroblastoma Genomics, Hopp-Children’s Cancer Center at the (NCT) Nationales Centrum für Tumorerkrankungen Heidelberg (KiTZ), Heidelberg, Germany
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Andres Florez
1Department of Neuroblastoma Genomics, Hopp-Children’s Cancer Center at the (NCT) Nationales Centrum für Tumorerkrankungen Heidelberg (KiTZ), Heidelberg, Germany
5Center for Systems Biology, Faculty of Arts and Sciences, Harvard University, Cambridge, MA, USA
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  • ORCID record for Andres Florez
Alica Torkov
1Department of Neuroblastoma Genomics, Hopp-Children’s Cancer Center at the (NCT) Nationales Centrum für Tumorerkrankungen Heidelberg (KiTZ), Heidelberg, Germany
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Daniel Dreidax
1Department of Neuroblastoma Genomics, Hopp-Children’s Cancer Center at the (NCT) Nationales Centrum für Tumorerkrankungen Heidelberg (KiTZ), Heidelberg, Germany
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Carl Herrmann
6Group of Cancer Regulatory Genomics B086, German Cancer Research Center (DKFZ), Heidelberg, Germany
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Konstantin Okonechnikov
7Department of Pediatric Neurooncology, Hopp-Children’s Cancer Center at the (NCT) Nationales Centrum für Tumorerkrankungen Heidelberg (KiTZ), Heidelberg, Germany
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Sara Ek
8Department of Immunotechnology, CREATE Health, Faculty of Engineering, Lund University, Lund, Sweden
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Ashwini Kumar Sharma
9Institute for Pharmacy and Molecular Biotechnology and BioQuant, Heidelberg University, Heidelberg, Germany
10Division of Theoretical Bioinformatics, German Cancer Research Center (DKFZ), Heidelberg, Germany
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Vitaliya Sagulenko
11School of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, Australia
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Frank Speleman
3Center for Medical Genetics, Ghent University, and Cancer Research Institute Ghent, Ghent, Belgium
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Kai-Oliver Henrich
1Department of Neuroblastoma Genomics, Hopp-Children’s Cancer Center at the (NCT) Nationales Centrum für Tumorerkrankungen Heidelberg (KiTZ), Heidelberg, Germany
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Frank Westermann
1Department of Neuroblastoma Genomics, Hopp-Children’s Cancer Center at the (NCT) Nationales Centrum für Tumorerkrankungen Heidelberg (KiTZ), Heidelberg, Germany
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  • For correspondence: f.westermann@dkfz.de
Published 3 March 2021. DOI: 10.26508/lsa.201900332
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Article Information

vol. 4 no. 5 e201900332
DOI 
https://doi.org/10.26508/lsa.201900332
PubMed 
33658318

Published By 
Life Science Alliance
Online ISSN 
2575-1077
History 
  • Received February 4, 2019
  • Revision received February 12, 2021
  • Accepted February 17, 2021
  • Published online March 3, 2021.

Copyright & Usage 
© 2021 Afanasyeva et al. This article is available under a Creative Commons License (Attribution 4.0 International, as described at https://creativecommons.org/licenses/by/4.0/).

Author Information

  1. Elena A Afanasyeva1⇑,
  2. Moritz Gartlgruber1,
  3. Tatsiana Ryl2,
  4. Bieke Decaesteker3,
  5. Geertrui Denecker3,
  6. Gregor Mönke4,
  7. Umut H Toprak1,
  8. Andres Florez1,5,
  9. Alica Torkov1,
  10. Daniel Dreidax1,
  11. Carl Herrmann6,
  12. Konstantin Okonechnikov7,
  13. Sara Ek8,
  14. Ashwini Kumar Sharma9,10,
  15. Vitaliya Sagulenko11,
  16. Frank Speleman3,
  17. Kai-Oliver Henrich1 and
  18. Frank Westermann1⇑
  1. 1Department of Neuroblastoma Genomics, Hopp-Children’s Cancer Center at the (NCT) Nationales Centrum für Tumorerkrankungen Heidelberg (KiTZ), Heidelberg, Germany
  2. 2Department of Neurosurgery, University of Duisburg Essen, Essen, Germany
  3. 3Center for Medical Genetics, Ghent University, and Cancer Research Institute Ghent, Ghent, Belgium
  4. 4European Molecular Biology Laboratories, Heidelberg, Germany
  5. 5Center for Systems Biology, Faculty of Arts and Sciences, Harvard University, Cambridge, MA, USA
  6. 6Group of Cancer Regulatory Genomics B086, German Cancer Research Center (DKFZ), Heidelberg, Germany
  7. 7Department of Pediatric Neurooncology, Hopp-Children’s Cancer Center at the (NCT) Nationales Centrum für Tumorerkrankungen Heidelberg (KiTZ), Heidelberg, Germany
  8. 8Department of Immunotechnology, CREATE Health, Faculty of Engineering, Lund University, Lund, Sweden
  9. 9Institute for Pharmacy and Molecular Biotechnology and BioQuant, Heidelberg University, Heidelberg, Germany
  10. 10Division of Theoretical Bioinformatics, German Cancer Research Center (DKFZ), Heidelberg, Germany
  11. 11School of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, Australia
  1. Correspondence: elena.afanasyeva{at}alumni.dkfz.de
  2. f.westermann{at}dkfz.de
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Kalirin suppression stops nucleokinetic migration
Elena A Afanasyeva, Moritz Gartlgruber, Tatsiana Ryl, Bieke Decaesteker, Geertrui Denecker, Gregor Mönke, Umut H Toprak, Andres Florez, Alica Torkov, Daniel Dreidax, Carl Herrmann, Konstantin Okonechnikov, Sara Ek, Ashwini Kumar Sharma, Vitaliya Sagulenko, Frank Speleman, Kai-Oliver Henrich, Frank Westermann
Life Science Alliance Mar 2021, 4 (5) e201900332; DOI: 10.26508/lsa.201900332

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Kalirin suppression stops nucleokinetic migration
Elena A Afanasyeva, Moritz Gartlgruber, Tatsiana Ryl, Bieke Decaesteker, Geertrui Denecker, Gregor Mönke, Umut H Toprak, Andres Florez, Alica Torkov, Daniel Dreidax, Carl Herrmann, Konstantin Okonechnikov, Sara Ek, Ashwini Kumar Sharma, Vitaliya Sagulenko, Frank Speleman, Kai-Oliver Henrich, Frank Westermann
Life Science Alliance Mar 2021, 4 (5) e201900332; DOI: 10.26508/lsa.201900332
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Volume 4, No. 5
May 2021
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