Harnessing reaction-based probes to preferentially target pancreatic β-cells and β-like cells

Sevim Kahraman; Debasish Manna; Ercument Dirice; Basudeb Maji; Jonnell Small; Bridget K Wagner; Amit Choudhary; Rohit N Kulkarni

doi:10.26508/lsa.202000840

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Harnessing reaction-based probes to preferentially target pancreatic β-cells and β-like cells

View ORCID ProfileSevim Kahraman, Debasish Manna, View ORCID ProfileErcument Dirice, Basudeb Maji, Jonnell Small, View ORCID ProfileBridget K Wagner, View ORCID ProfileAmit Choudhary Correspondence email, View ORCID ProfileRohit N Kulkarni Correspondence email

Sevim Kahraman

1Islet Cell and Regenerative Biology, Joslin Diabetes Center, Department of Medicine, Brigham and Women’s Hospital, Harvard Stem Cell Institute, Harvard Medical School, Boston, MA, USA

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ORCID record for Sevim Kahraman

Debasish Manna

2Chemical Biology and Therapeutics Science Program, Broad Institute of MIT and Harvard, Cambridge, MA, USA

3Department of Medicine, Harvard Medical School, Boston, MA, USA

4Divisions of Renal Medicine and Engineering, Brigham and Women’s Hospital, Boston, MA, USA

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Ercument Dirice

1Islet Cell and Regenerative Biology, Joslin Diabetes Center, Department of Medicine, Brigham and Women’s Hospital, Harvard Stem Cell Institute, Harvard Medical School, Boston, MA, USA

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ORCID record for Ercument Dirice

Basudeb Maji

2Chemical Biology and Therapeutics Science Program, Broad Institute of MIT and Harvard, Cambridge, MA, USA

3Department of Medicine, Harvard Medical School, Boston, MA, USA

4Divisions of Renal Medicine and Engineering, Brigham and Women’s Hospital, Boston, MA, USA

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Jonnell Small

2Chemical Biology and Therapeutics Science Program, Broad Institute of MIT and Harvard, Cambridge, MA, USA

5Chemical Biology Program, Harvard University, Cambridge, MA, USA

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Bridget K Wagner

2Chemical Biology and Therapeutics Science Program, Broad Institute of MIT and Harvard, Cambridge, MA, USA

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ORCID record for Bridget K Wagner

Amit Choudhary

2Chemical Biology and Therapeutics Science Program, Broad Institute of MIT and Harvard, Cambridge, MA, USA

3Department of Medicine, Harvard Medical School, Boston, MA, USA

4Divisions of Renal Medicine and Engineering, Brigham and Women’s Hospital, Boston, MA, USA

5Chemical Biology Program, Harvard University, Cambridge, MA, USA

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ORCID record for Amit Choudhary
For correspondence: achoudhary@bwh.harvard.edu

Rohit N Kulkarni

1Islet Cell and Regenerative Biology, Joslin Diabetes Center, Department of Medicine, Brigham and Women’s Hospital, Harvard Stem Cell Institute, Harvard Medical School, Boston, MA, USA

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ORCID record for Rohit N Kulkarni
For correspondence: Rohit.Kulkarni@joslin.harvard.edu

Published 29 January 2021. DOI: 10.26508/lsa.202000840

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Developing approaches to target β-cells

Sevim Kahraman, Debasish Manna, Ercument Dirice, Basudeb Maji, Jonnell Small, Bridget K Wagner, Amit Choudhary, Rohit N Kulkarni

Life Science Alliance Jan 2021, 4 (4) e202000840; DOI: 10.26508/lsa.202000840

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Developing approaches to target β-cells

Sevim Kahraman, Debasish Manna, Ercument Dirice, Basudeb Maji, Jonnell Small, Bridget K Wagner, Amit Choudhary, Rohit N Kulkarni

Life Science Alliance Jan 2021, 4 (4) e202000840; DOI: 10.26508/lsa.202000840

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