Short-term IL-15 priming leaves a long-lasting signalling imprint in mouse NK cells independently of a metabolic switch

Thuy T Luu; Laurent Schmied; Ngoc-Anh Nguyen; Clotilde Wiel; Stephan Meinke; Dara K Mohammad; Martin Bergö; Evren Alici; Nadir Kadri; Sridharan Ganesan; Petter Höglund

doi:10.26508/lsa.202000723

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Short-term IL-15 priming leaves a long-lasting signalling imprint in mouse NK cells independently of a metabolic switch

View ORCID ProfileThuy T Luu, View ORCID ProfileLaurent Schmied, View ORCID ProfileNgoc-Anh Nguyen, Clotilde Wiel, View ORCID ProfileStephan Meinke, View ORCID ProfileDara K Mohammad, View ORCID ProfileMartin Bergö, Evren Alici, Nadir Kadri, View ORCID ProfileSridharan Ganesan, View ORCID ProfilePetter Höglund Correspondence email

Thuy T Luu

1Department of Medicine Huddinge, Centre for Haematology and Regenerative Medicine (HERM), Karolinska Institutet, Huddinge, Sweden

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Laurent Schmied

1Department of Medicine Huddinge, Centre for Haematology and Regenerative Medicine (HERM), Karolinska Institutet, Huddinge, Sweden

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Ngoc-Anh Nguyen

1Department of Medicine Huddinge, Centre for Haematology and Regenerative Medicine (HERM), Karolinska Institutet, Huddinge, Sweden

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Clotilde Wiel

2Department of Biosciences and Nutrition, Karolinska Institutet, Huddinge, Sweden

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Stephan Meinke

1Department of Medicine Huddinge, Centre for Haematology and Regenerative Medicine (HERM), Karolinska Institutet, Huddinge, Sweden

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Dara K Mohammad

1Department of Medicine Huddinge, Centre for Haematology and Regenerative Medicine (HERM), Karolinska Institutet, Huddinge, Sweden

3Department of Food Technology, College of Agricultural Engineering Sciences, Salahaddin University-Erbil, KRG-Kurdistan Region, Iraq

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Martin Bergö

2Department of Biosciences and Nutrition, Karolinska Institutet, Huddinge, Sweden

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Evren Alici

1Department of Medicine Huddinge, Centre for Haematology and Regenerative Medicine (HERM), Karolinska Institutet, Huddinge, Sweden

4Cell Therapy Institute, Nova Southeastern University, Fort Lauderdale, FL, USA

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Nadir Kadri

1Department of Medicine Huddinge, Centre for Haematology and Regenerative Medicine (HERM), Karolinska Institutet, Huddinge, Sweden

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Sridharan Ganesan

1Department of Medicine Huddinge, Centre for Haematology and Regenerative Medicine (HERM), Karolinska Institutet, Huddinge, Sweden

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Petter Höglund

1Department of Medicine Huddinge, Centre for Haematology and Regenerative Medicine (HERM), Karolinska Institutet, Huddinge, Sweden

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For correspondence: petter.hoglund@ki.se

Published 16 February 2021. DOI: 10.26508/lsa.202000723

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Improved and reversible function of NK cells by brief IL-15 encounter

Thuy T Luu, Laurent Schmied, Ngoc-Anh Nguyen, Clotilde Wiel, Stephan Meinke, Dara K Mohammad, Martin Bergö, Evren Alici, Nadir Kadri, Sridharan Ganesan, Petter Höglund

Life Science Alliance Feb 2021, 4 (4) e202000723; DOI: 10.26508/lsa.202000723

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Improved and reversible function of NK cells by brief IL-15 encounter

Thuy T Luu, Laurent Schmied, Ngoc-Anh Nguyen, Clotilde Wiel, Stephan Meinke, Dara K Mohammad, Martin Bergö, Evren Alici, Nadir Kadri, Sridharan Ganesan, Petter Höglund

Life Science Alliance Feb 2021, 4 (4) e202000723; DOI: 10.26508/lsa.202000723

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