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Research Article
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Genetic and stochastic influences upon tumor formation and tumor types in Li-Fraumeni mouse models

View ORCID ProfileChang S Chan  Correspondence email, Yvonne Sun, Hua Ke, View ORCID ProfileYuhan Zhao, View ORCID ProfileMerzu Belete, Cen Zhang, Zhaohui Feng, View ORCID ProfileArnold J Levine  Correspondence email, View ORCID ProfileWenwei Hu  Correspondence email
Chang S Chan
1Rutgers Cancer Institute of New Jersey, Rutgers, State University of New Jersey, New Brunswick, NJ, USA
2Department of Medicine, Rutgers Robert Wood Johnson Medical School, Rutgers, State University of New Jersey, New Brunswick, NJ, USA
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  • ORCID record for Chang S Chan
  • For correspondence: chanc3@cinj.rutgers.edu
Yvonne Sun
3PMV Pharma, Cranbury, NJ, USA
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Hua Ke
1Rutgers Cancer Institute of New Jersey, Rutgers, State University of New Jersey, New Brunswick, NJ, USA
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Yuhan Zhao
1Rutgers Cancer Institute of New Jersey, Rutgers, State University of New Jersey, New Brunswick, NJ, USA
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  • ORCID record for Yuhan Zhao
Merzu Belete
1Rutgers Cancer Institute of New Jersey, Rutgers, State University of New Jersey, New Brunswick, NJ, USA
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  • ORCID record for Merzu Belete
Cen Zhang
1Rutgers Cancer Institute of New Jersey, Rutgers, State University of New Jersey, New Brunswick, NJ, USA
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Zhaohui Feng
1Rutgers Cancer Institute of New Jersey, Rutgers, State University of New Jersey, New Brunswick, NJ, USA
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Arnold J Levine
4Simons Center for Systems Biology, Institute for Advanced Study, Princeton, NJ, USA
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  • ORCID record for Arnold J Levine
  • For correspondence: alevine@ias.edu
Wenwei Hu
1Rutgers Cancer Institute of New Jersey, Rutgers, State University of New Jersey, New Brunswick, NJ, USA
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  • ORCID record for Wenwei Hu
  • For correspondence: wh221@cinj.rutgers.edu
Published 29 December 2020. DOI: 10.26508/lsa.202000952
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Article Information

vol. 4 no. 3 e202000952
DOI 
https://doi.org/10.26508/lsa.202000952
PubMed 
33376133

Published By 
Life Science Alliance
Online ISSN 
2575-1077
History 
  • Received November 3, 2020
  • Revision received December 14, 2020
  • Accepted December 15, 2020
  • Published online December 29, 2020.

Copyright & Usage 
© 2020 Chan et al. This article is available under a Creative Commons License (Attribution 4.0 International, as described at https://creativecommons.org/licenses/by/4.0/).

Author Information

  1. Chang S Chan1,2⇑,
  2. Yvonne Sun3,
  3. Hua Ke1,
  4. Yuhan Zhao1,
  5. Merzu Belete1,
  6. Cen Zhang1,
  7. Zhaohui Feng1,
  8. Arnold J Levine4⇑ and
  9. Wenwei Hu1⇑
  1. 1Rutgers Cancer Institute of New Jersey, Rutgers, State University of New Jersey, New Brunswick, NJ, USA
  2. 2Department of Medicine, Rutgers Robert Wood Johnson Medical School, Rutgers, State University of New Jersey, New Brunswick, NJ, USA
  3. 3PMV Pharma, Cranbury, NJ, USA
  4. 4Simons Center for Systems Biology, Institute for Advanced Study, Princeton, NJ, USA
  1. Correspondence: alevine{at}ias.edu
  2. wh221{at}cinj.rutgers.edu
  3. chanc3{at}cinj.rutgers.edu
View Full Text

Funding

  • National Institutes of Health/National Cancer Institute

    P01CA087497-18
  • Rutgers Cancer Institute and Robert Wood Johnson Foundation

    CS Chan
  • National Insitutes of Health (NIH)/National Cancer Institute

    R01CA203965
  • DoD

    W81XWH-18-10238
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Genetic and stochastic factors in Li-Fraumeni mice
Chang S Chan, Yvonne Sun, Hua Ke, Yuhan Zhao, Merzu Belete, Cen Zhang, Zhaohui Feng, Arnold J Levine, Wenwei Hu
Life Science Alliance Dec 2020, 4 (3) e202000952; DOI: 10.26508/lsa.202000952

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Genetic and stochastic factors in Li-Fraumeni mice
Chang S Chan, Yvonne Sun, Hua Ke, Yuhan Zhao, Merzu Belete, Cen Zhang, Zhaohui Feng, Arnold J Levine, Wenwei Hu
Life Science Alliance Dec 2020, 4 (3) e202000952; DOI: 10.26508/lsa.202000952
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Volume 4, No. 3
March 2021
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  • Cancer
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