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Research Article
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Open Access

Paneth cell–derived growth factors support tumorigenesis in the small intestine

View ORCID ProfileQing Chen, View ORCID ProfileKohei Suzuki, Luis Sifuentes-Dominguez, Naoteru Miyata, Jie Song, Adam Lopez, View ORCID ProfilePetro Starokadomskyy, Purva Gopal, Igor Dozmorov, Shuai Tan, Bujun Ge, View ORCID ProfileEzra Burstein  Correspondence email
Qing Chen
1Department of General Surgery, Shanghai Tenth People’s Hospital, Tongji University School of Medicine, Shanghai, China
2Department of Internal Medicine, University of Texas (UT) Southwestern Medical Center, Dallas, TX, USA
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  • ORCID record for Qing Chen
Kohei Suzuki
2Department of Internal Medicine, University of Texas (UT) Southwestern Medical Center, Dallas, TX, USA
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  • ORCID record for Kohei Suzuki
Luis Sifuentes-Dominguez
2Department of Internal Medicine, University of Texas (UT) Southwestern Medical Center, Dallas, TX, USA
3Department of Pediatrics, UT Southwestern Medical Center, Dallas, TX, USA
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Naoteru Miyata
2Department of Internal Medicine, University of Texas (UT) Southwestern Medical Center, Dallas, TX, USA
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Jie Song
2Department of Internal Medicine, University of Texas (UT) Southwestern Medical Center, Dallas, TX, USA
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Adam Lopez
2Department of Internal Medicine, University of Texas (UT) Southwestern Medical Center, Dallas, TX, USA
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Petro Starokadomskyy
2Department of Internal Medicine, University of Texas (UT) Southwestern Medical Center, Dallas, TX, USA
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  • ORCID record for Petro Starokadomskyy
Purva Gopal
4Department of Pathology, UT Southwestern Medical Center, Dallas, TX, USA
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Igor Dozmorov
5Department of Immunology, UT Southwestern Medical Center, Dallas, TX, USA
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Shuai Tan
2Department of Internal Medicine, University of Texas (UT) Southwestern Medical Center, Dallas, TX, USA
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Bujun Ge
7Department of General Surgery, Shanghai Tongji Hospital, Tongji University School of Medicine, Shanghai, China
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Ezra Burstein
2Department of Internal Medicine, University of Texas (UT) Southwestern Medical Center, Dallas, TX, USA
6Department of Molecular Biology, UT Southwestern Medical Center, Dallas, TX, USA
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  • ORCID record for Ezra Burstein
  • For correspondence: Ezra.Burstein@UTSouthwestern.edu
Published 28 December 2020. DOI: 10.26508/lsa.202000934
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Article Information

vol. 4 no. 3 e202000934
DOI 
https://doi.org/10.26508/lsa.202000934
PubMed 
33372038

Published By 
Life Science Alliance
Online ISSN 
2575-1077
History 
  • Received October 13, 2020
  • Revision received December 9, 2020
  • Accepted December 11, 2020
  • Published online December 28, 2020.

Copyright & Usage 
© 2020 Chen et al. This article is available under a Creative Commons License (Attribution 4.0 International, as described at https://creativecommons.org/licenses/by/4.0/).

Author Information

  1. Qing Chen1,2,
  2. Kohei Suzuki2,
  3. Luis Sifuentes-Dominguez2,3,
  4. Naoteru Miyata2,
  5. Jie Song2,
  6. Adam Lopez2,
  7. Petro Starokadomskyy2,
  8. Purva Gopal4,
  9. Igor Dozmorov5,
  10. Shuai Tan2,
  11. Bujun Ge7 and
  12. Ezra Burstein2,6⇑
  1. 1Department of General Surgery, Shanghai Tenth People’s Hospital, Tongji University School of Medicine, Shanghai, China
  2. 2Department of Internal Medicine, University of Texas (UT) Southwestern Medical Center, Dallas, TX, USA
  3. 3Department of Pediatrics, UT Southwestern Medical Center, Dallas, TX, USA
  4. 4Department of Pathology, UT Southwestern Medical Center, Dallas, TX, USA
  5. 5Department of Immunology, UT Southwestern Medical Center, Dallas, TX, USA
  6. 6Department of Molecular Biology, UT Southwestern Medical Center, Dallas, TX, USA
  7. 7Department of General Surgery, Shanghai Tongji Hospital, Tongji University School of Medicine, Shanghai, China
  1. Correspondence: Ezra.Burstein{at}UTSouthwestern.edu
View Full Text

Funding

  • University of Texas Southwestern Medical Center

    E Burstein
  • National Institutes of Health

    R01 DK073639 and R01 DK107733
    E Burstein
  • National Institutes of Health

    K12 HD-068369
    L Sifuentes-Dominguez
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Paneth cells in tumor formation
Qing Chen, Kohei Suzuki, Luis Sifuentes-Dominguez, Naoteru Miyata, Jie Song, Adam Lopez, Petro Starokadomskyy, Purva Gopal, Igor Dozmorov, Shuai Tan, Bujun Ge, Ezra Burstein
Life Science Alliance Dec 2020, 4 (3) e202000934; DOI: 10.26508/lsa.202000934

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Paneth cells in tumor formation
Qing Chen, Kohei Suzuki, Luis Sifuentes-Dominguez, Naoteru Miyata, Jie Song, Adam Lopez, Petro Starokadomskyy, Purva Gopal, Igor Dozmorov, Shuai Tan, Bujun Ge, Ezra Burstein
Life Science Alliance Dec 2020, 4 (3) e202000934; DOI: 10.26508/lsa.202000934
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Volume 4, No. 3
March 2021
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