Modulation of Aub–TDRD interactions elucidates piRNA amplification and germplasm formation

Nicholas Vrettos; Manolis Maragkakis; Panagiotis Alexiou; Paraskevi Sgourdou; Fadia Ibrahim; Daniel Palmieri; Yohei Kirino; Zissimos Mourelatos

doi:10.26508/lsa.202000912

Research Article

Open Access

Modulation of Aub–TDRD interactions elucidates piRNA amplification and germplasm formation

Nicholas Vrettos, Manolis Maragkakis, Panagiotis Alexiou, Paraskevi Sgourdou, Fadia Ibrahim, View ORCID ProfileDaniel Palmieri, View ORCID ProfileYohei Kirino, View ORCID ProfileZissimos Mourelatos Correspondence email

Nicholas Vrettos

1Division of Neuropathology, Departments of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA, USA

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Manolis Maragkakis

2Laboratory of Genetics and Genomics, National Institute on Aging, Intramural Research Program, National Institutes of Health, Baltimore, MD, USA

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Panagiotis Alexiou

3Central European Institute of Technology, Brno, Czech Republic

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Paraskevi Sgourdou

4Departments of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA

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Fadia Ibrahim

1Division of Neuropathology, Departments of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA, USA

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Daniel Palmieri

1Division of Neuropathology, Departments of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA, USA

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ORCID record for Daniel Palmieri

Yohei Kirino

5Computational Medicine Center, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA, USA

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Zissimos Mourelatos

1Division of Neuropathology, Departments of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA, USA

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ORCID record for Zissimos Mourelatos
For correspondence: mourelaz@uphs.upenn.edu

Published 29 December 2020. DOI: 10.26508/lsa.202000912

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Aub methylation in piRNA amplification and germplasm formation