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Autoimmune anti-DNA and anti-phosphatidylserine antibodies predict development of severe COVID-19

Claudia Gomes, Marisol Zuniga, View ORCID ProfileKelly A Crotty, Kun Qian, Nubia Catalina Tovar, Lawrence Hsu Lin, Kimon V Argyropoulos, Robert Clancy, Peter Izmirly, Jill Buyon, David C Lee, View ORCID ProfileMaria Fernanda Yasnot-Acosta, Huilin Li, Paolo Cotzia, View ORCID ProfileAna Rodriguez  Correspondence email
Claudia Gomes
1Department of Microbiology, New York University Grossman School of Medicine, New York, NY, USA
Roles: Data curation, Investigation, Methodology
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Marisol Zuniga
1Department of Microbiology, New York University Grossman School of Medicine, New York, NY, USA
Roles: Data curation, Investigation, Methodology
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Kelly A Crotty
1Department of Microbiology, New York University Grossman School of Medicine, New York, NY, USA
Roles: Data curation, Investigation, Methodology
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  • ORCID record for Kelly A Crotty
Kun Qian
2Division of Biostatistics, Department of Population Health, New York University Grossman School of Medicine, New York, NY, USA
Roles: Formal analysis
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Nubia Catalina Tovar
1Department of Microbiology, New York University Grossman School of Medicine, New York, NY, USA
3Universidad de Córdoba, Montería, Córdoba, Colombia
4Universidad Del Sinú, Montería, Córdoba, Colombia
Roles: Data curation, Investigation, Methodology
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Lawrence Hsu Lin
5Department of Pathology, New York University Grossman School of Medicine, New York, NY, USA
Roles: Resources, Data curation, Investigation, Methodology, Patient recruitment and sample collection
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Kimon V Argyropoulos
5Department of Pathology, New York University Grossman School of Medicine, New York, NY, USA
Roles: Resources, Patient recruitment and sample collection, Writing—review and editing
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Robert Clancy
6Division of Rheumatology, Department of Medicine, New York University Grossman School of Medicine, New York, NY, USA
Roles: Resources
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Peter Izmirly
6Division of Rheumatology, Department of Medicine, New York University Grossman School of Medicine, New York, NY, USA
Roles: Resources
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Jill Buyon
6Division of Rheumatology, Department of Medicine, New York University Grossman School of Medicine, New York, NY, USA
Roles: Resources
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David C Lee
7Department of Emergency Medicine, New York University Grossman School of Medicine, New York, NY, USA
Roles: Conceptualization, Formal analysis
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Maria Fernanda Yasnot-Acosta
3Universidad de Córdoba, Montería, Córdoba, Colombia
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  • ORCID record for Maria Fernanda Yasnot-Acosta
Huilin Li
2Division of Biostatistics, Department of Population Health, New York University Grossman School of Medicine, New York, NY, USA
Roles: Formal analysis
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Paolo Cotzia
5Department of Pathology, New York University Grossman School of Medicine, New York, NY, USA
Roles: Patient recruitment and sample collection, writing—review and editing
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Ana Rodriguez
1Department of Microbiology, New York University Grossman School of Medicine, New York, NY, USA
Roles: Conceptualization, Data curation, Formal analysis, Supervision, Funding acquisition, Writing—original draft, review, and editing
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  • ORCID record for Ana Rodriguez
  • For correspondence: ana.rodriguez@nyumc.org
Published 9 September 2021. DOI: 10.26508/lsa.202101180
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Article Information

vol. 4 no. 11 e202101180
DOI 
https://doi.org/10.26508/lsa.202101180
PubMed 
34504035

Published By 
Life Science Alliance
Online ISSN 
2575-1077
History 
  • Received July 29, 2021
  • Revision received August 18, 2021
  • Accepted August 18, 2021
  • Published online September 9, 2021.

Copyright & Usage 
© 2021 Gomes et al. This article is available under a Creative Commons License (Attribution 4.0 International, as described at https://creativecommons.org/licenses/by/4.0/).

Author Information

  1. Claudia Gomes, Data curation, Investigation, Methodology1,*,
  2. Marisol Zuniga, Data curation, Investigation, Methodology1,*,
  3. Kelly A Crotty, Data curation, Investigation, Methodology1,
  4. Kun Qian, Formal analysis2,
  5. Nubia Catalina Tovar, Data curation, Investigation, Methodology1,3,4,
  6. Lawrence Hsu Lin, Resources, Data curation, Investigation, Methodology, Patient recruitment and sample collection5,
  7. Kimon V Argyropoulos, Resources, Patient recruitment and sample collection, Writing—review and editing5,
  8. Robert Clancy, Resources6,
  9. Peter Izmirly, Resources6,
  10. Jill Buyon, Resources6,
  11. David C Lee, Conceptualization, Formal analysis7,
  12. Maria Fernanda Yasnot-Acosta, Resources3,
  13. Huilin Li, Formal analysis2,
  14. Paolo Cotzia, Patient recruitment and sample collection, writing—review and editing5 and
  15. Ana Rodriguez, Conceptualization, Data curation, Formal analysis, Supervision, Funding acquisition, Writing—original draft, review, and editing1⇑
  1. 1Department of Microbiology, New York University Grossman School of Medicine, New York, NY, USA
  2. 2Division of Biostatistics, Department of Population Health, New York University Grossman School of Medicine, New York, NY, USA
  3. 3Universidad de Córdoba, Montería, Córdoba, Colombia
  4. 4Universidad Del Sinú, Montería, Córdoba, Colombia
  5. 5Department of Pathology, New York University Grossman School of Medicine, New York, NY, USA
  6. 6Division of Rheumatology, Department of Medicine, New York University Grossman School of Medicine, New York, NY, USA
  7. 7Department of Emergency Medicine, New York University Grossman School of Medicine, New York, NY, USA
  1. Correspondence: ana.rodriguez{at}nyumc.org
  1. ↵* Claudia Gomes and Marisol Zuniga contributed equally to this work

View Full Text

Funding

  • New York University Langone COVID-19 Special Fund

  • National Institutes of Health/National Institute of Arthritis and Musculoskeletal and Skin Diseases

    P50 AR07059
  • Bloomberg Philanthropies COVID-19 Response Initiative Grant

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Autoantibodies predict COVID-19 severity
Claudia Gomes, Marisol Zuniga, Kelly A Crotty, Kun Qian, Nubia Catalina Tovar, Lawrence Hsu Lin, Kimon V Argyropoulos, Robert Clancy, Peter Izmirly, Jill Buyon, David C Lee, Maria Fernanda Yasnot-Acosta, Huilin Li, Paolo Cotzia, Ana Rodriguez
Life Science Alliance Sep 2021, 4 (11) e202101180; DOI: 10.26508/lsa.202101180

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Autoantibodies predict COVID-19 severity
Claudia Gomes, Marisol Zuniga, Kelly A Crotty, Kun Qian, Nubia Catalina Tovar, Lawrence Hsu Lin, Kimon V Argyropoulos, Robert Clancy, Peter Izmirly, Jill Buyon, David C Lee, Maria Fernanda Yasnot-Acosta, Huilin Li, Paolo Cotzia, Ana Rodriguez
Life Science Alliance Sep 2021, 4 (11) e202101180; DOI: 10.26508/lsa.202101180
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Volume 4, No. 11
November 2021
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