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Research Article
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Paralogous synthetic lethality underlies genetic dependencies of the cancer-mutated gene STAG2

Melanie L Bailey, David Tieu, Andrea Habsid, Amy Hin Yan Tong, Katherine Chan, Jason Moffat, View ORCID ProfilePhilip Hieter  Correspondence email
Melanie L Bailey
1Michael Smith Laboratories, University of British Columbia, Vancouver, Canada
Roles: Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Writing—original draft, review, and editing
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David Tieu
2Donnelly Centre, University of Toronto, Toronto, Canada
Roles: Investigation, Writing—review and editing
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Andrea Habsid
2Donnelly Centre, University of Toronto, Toronto, Canada
Roles: Investigation, Writing—review and editing
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Amy Hin Yan Tong
2Donnelly Centre, University of Toronto, Toronto, Canada
Roles: Investigation, Writing—review and editing
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Katherine Chan
2Donnelly Centre, University of Toronto, Toronto, Canada
Roles: Investigation, Methodology, Writing—review and editing
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Jason Moffat
2Donnelly Centre, University of Toronto, Toronto, Canada
3Department of Molecular Genetics, University of Toronto, Toronto, Canada
4Institute of Biomedical Engineering, University of Toronto, Toronto, Canada
Roles: Conceptualization, Funding acquisition, Investigation, Writing—review and editing
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Philip Hieter
1Michael Smith Laboratories, University of British Columbia, Vancouver, Canada
Roles: Conceptualization, Funding acquisition, Writing—review and editing
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  • ORCID record for Philip Hieter
  • For correspondence: hieter@msl.ubc.ca
Published 30 August 2021. DOI: 10.26508/lsa.202101083
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Article Information

vol. 4 no. 11 e202101083
DOI 
https://doi.org/10.26508/lsa.202101083
PubMed 
34462321

Published By 
Life Science Alliance
Online ISSN 
2575-1077
History 
  • Received April 1, 2021
  • Revision received August 14, 2021
  • Accepted August 16, 2021
  • Published online August 30, 2021.

Copyright & Usage 
© 2021 Bailey et al. This article is available under a Creative Commons License (Attribution 4.0 International, as described at https://creativecommons.org/licenses/by/4.0/).

Author Information

  1. Melanie L Bailey, Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Writing—original draft, review, and editing1,
  2. David Tieu, Investigation, Writing—review and editing2,
  3. Andrea Habsid, Investigation, Writing—review and editing2,
  4. Amy Hin Yan Tong, Investigation, Writing—review and editing2,
  5. Katherine Chan, Investigation, Methodology, Writing—review and editing2,
  6. Jason Moffat, Conceptualization, Funding acquisition, Investigation, Writing—review and editing2,3,4 and
  7. Philip Hieter, Conceptualization, Funding acquisition, Writing—review and editing1⇑
  1. 1Michael Smith Laboratories, University of British Columbia, Vancouver, Canada
  2. 2Donnelly Centre, University of Toronto, Toronto, Canada
  3. 3Department of Molecular Genetics, University of Toronto, Toronto, Canada
  4. 4Institute of Biomedical Engineering, University of Toronto, Toronto, Canada
  1. Correspondence: hieter{at}msl.ubc.ca
View Full Text

Funding

  • Canadian Institutes for Health Research

    FDN 148449
    P Hieter
  • Canadian Institute for Advanced Research Genetic Networks Catalyst

    P Hieter, J Moffat
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Genetic interactions of STAG2
Melanie L Bailey, David Tieu, Andrea Habsid, Amy Hin Yan Tong, Katherine Chan, Jason Moffat, Philip Hieter
Life Science Alliance Aug 2021, 4 (11) e202101083; DOI: 10.26508/lsa.202101083

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Genetic interactions of STAG2
Melanie L Bailey, David Tieu, Andrea Habsid, Amy Hin Yan Tong, Katherine Chan, Jason Moffat, Philip Hieter
Life Science Alliance Aug 2021, 4 (11) e202101083; DOI: 10.26508/lsa.202101083
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Volume 4, No. 11
November 2021
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Subjects

  • Cancer
  • Genetics, Gene Therapy & Genetic Disease
  • Genomics & Functional Genomics

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