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Research Article
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The Th1 cell regulatory circuitry is largely conserved between human and mouse

View ORCID ProfileStephen Henderson, Venu Pullabhatla, Arnulf Hertweck, Emanuele de Rinaldis, View ORCID ProfileJavier Herrero, View ORCID ProfileGraham M Lord  Correspondence email, View ORCID ProfileRichard G Jenner  Correspondence email
Stephen Henderson
1Bill Lyons Informatics Centre, UCL Cancer Institute and CRUK UCL Centre, University College London, London, UK
Roles: Data curation, Software, Formal analysis, Investigation, Visualization, Methodology, Writing—review and editing
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  • ORCID record for Stephen Henderson
Venu Pullabhatla
2NIHR Biomedical Research Centre at Guy’s and St Thomas’ Hospital and King’s College London, London, UK
Roles: Data curation, Formal analysis, Methodology
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Arnulf Hertweck
3Regulatory Genomics Group, UCL Cancer Institute and CRUK UCL Centre, University College London, London, UK
Roles: Formal analysis, Investigation, Methodology
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Emanuele de Rinaldis
2NIHR Biomedical Research Centre at Guy’s and St Thomas’ Hospital and King’s College London, London, UK
Roles: Supervision
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Javier Herrero
1Bill Lyons Informatics Centre, UCL Cancer Institute and CRUK UCL Centre, University College London, London, UK
Roles: Supervision, Writing—review and editing
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  • ORCID record for Javier Herrero
Graham M Lord
2NIHR Biomedical Research Centre at Guy’s and St Thomas’ Hospital and King’s College London, London, UK
4School of Immunology and Microbial Sciences, King’s College London, London, UK
5Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK
Roles: Conceptualization, Funding acquisition, Project administration, Writing—review and editing
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  • ORCID record for Graham M Lord
  • For correspondence: graham.lord@manchester.ac.uk
Richard G Jenner
3Regulatory Genomics Group, UCL Cancer Institute and CRUK UCL Centre, University College London, London, UK
Roles: Conceptualization, Formal analysis, Supervision, Funding acquisition, Investigation, Visualization, Project administration, Writing—original draft, review, and editing
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  • For correspondence: r.jenner@ucl.ac.uk
Published 16 September 2021. DOI: 10.26508/lsa.202101075
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Article Information

vol. 4 no. 11 e202101075
DOI 
https://doi.org/10.26508/lsa.202101075
PubMed 
34531288

Published By 
Life Science Alliance
Online ISSN 
2575-1077
History 
  • Received March 24, 2021
  • Revision received September 6, 2021
  • Accepted September 7, 2021
  • Published online September 16, 2021.

Copyright & Usage 
© 2021 Henderson et al. This article is available under a Creative Commons License (Attribution 4.0 International, as described at https://creativecommons.org/licenses/by/4.0/).

Author Information

  1. Stephen Henderson, Data curation, Software, Formal analysis, Investigation, Visualization, Methodology, Writing—review and editing1,
  2. Venu Pullabhatla, Data curation, Formal analysis, Methodology2,
  3. Arnulf Hertweck, Formal analysis, Investigation, Methodology3,
  4. Emanuele de Rinaldis, Supervision2,
  5. Javier Herrero, Supervision, Writing—review and editing1,
  6. Graham M Lord, Conceptualization, Funding acquisition, Project administration, Writing—review and editing2,4,5⇑ and
  7. Richard G Jenner, Conceptualization, Formal analysis, Supervision, Funding acquisition, Investigation, Visualization, Project administration, Writing—original draft, review, and editing3⇑
  1. 1Bill Lyons Informatics Centre, UCL Cancer Institute and CRUK UCL Centre, University College London, London, UK
  2. 2NIHR Biomedical Research Centre at Guy’s and St Thomas’ Hospital and King’s College London, London, UK
  3. 3Regulatory Genomics Group, UCL Cancer Institute and CRUK UCL Centre, University College London, London, UK
  4. 4School of Immunology and Microbial Sciences, King’s College London, London, UK
  5. 5Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK
  1. Correspondence: r.jenner{at}ucl.ac.uk
  2. graham.lord{at}manchester.ac.uk
  • Venu Pullabhatla’s present address is Oxford Gene Technology, Oxford, UK

  • Emanuele de Rinaldis’s present address is Sanofi, Cambridge, MA, USA

  • Arnulf Hertweck’s present address is Nucleome Therapeutics Limited, Oxford, UK

View Full Text

Funding

  • MRC grants

    MR/M003493/1 and MR/R001413/1
    RG Jenner, GM Lord
  • Cancer Research UK-University College London (CRUK-UCL) Centre

    C416/A25145
  • National Institute for Health (NIHR) Biomedical Research Centres

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Conservation of Th1 regulatory circuitry
Stephen Henderson, Venu Pullabhatla, Arnulf Hertweck, Emanuele de Rinaldis, Javier Herrero, Graham M Lord, Richard G Jenner
Life Science Alliance Sep 2021, 4 (11) e202101075; DOI: 10.26508/lsa.202101075

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Conservation of Th1 regulatory circuitry
Stephen Henderson, Venu Pullabhatla, Arnulf Hertweck, Emanuele de Rinaldis, Javier Herrero, Graham M Lord, Richard G Jenner
Life Science Alliance Sep 2021, 4 (11) e202101075; DOI: 10.26508/lsa.202101075
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Volume 4, No. 11
November 2021
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