Research Article
Open Access
High levels of TFAM repress mammalian mitochondrial DNA transcription in vivo
View ORCID ProfileNina A Bonekamp Correspondence email, View ORCID ProfileMin Jiang, View ORCID ProfileElisa Motori, View ORCID ProfileRodolfo Garcia Villegas, Camilla Koolmeister, Ilian Atanassov, Andrea Mesaros, Chan Bae Park, View ORCID ProfileNils-Göran Larsson Correspondence email
Nina A Bonekamp
1Department of Mitochondrial Biology, Max Planck Institute for Biology of Ageing, Cologne, Germany
Roles: Conceptualization, Data curation, Formal analysis, Supervision, Validation, Investigation, Visualization, Methodology, Project administration, Writing—original draft, review, and editing
Min Jiang
1Department of Mitochondrial Biology, Max Planck Institute for Biology of Ageing, Cologne, Germany
2Zhejiang Provincial Laboratory of Life Sciences and Biomedicine, Key Laboratory of Growth Regulation and Transformation Research of Zhejiang Province, School of Life Sciences, Westlake University, Hangzhou, China
Roles: Data curation, Investigation, Methodology
Elisa Motori
1Department of Mitochondrial Biology, Max Planck Institute for Biology of Ageing, Cologne, Germany
3Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), Cologne, Germany
Roles: Data curation, Formal analysis, Investigation, Methodology
Rodolfo Garcia Villegas
4Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden
Roles: Data curation, Formal analysis, Investigation
Camilla Koolmeister
4Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden
Roles: Methodology
Ilian Atanassov
5Proteomics Core Facility, Max Planck Institute for Biology of Ageing, Cologne, Germany
Roles: Data curation, Formal analysis, Investigation
Andrea Mesaros
6Phenotyping Core Facility, Max Planck Institute for Biology of Ageing, Cologne, Germany
Roles: Formal analysis, Investigation
Chan Bae Park
7Ajou University, Suwon, Republic of Korea
Roles: Methodology
Nils-Göran Larsson
1Department of Mitochondrial Biology, Max Planck Institute for Biology of Ageing, Cologne, Germany
4Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden
Roles: Conceptualization, Resources, Supervision, Funding acquisition, Project administration, Writing—original draft, review, and editing
Published 30 August 2021. DOI: 10.26508/lsa.202101034
Levels of TFAM affect mtDNA expression in vivo
Nina A Bonekamp, Min Jiang, Elisa Motori, Rodolfo Garcia Villegas, Camilla Koolmeister, Ilian Atanassov, Andrea Mesaros, Chan Bae Park, Nils-Göran Larsson
Life Science Alliance Aug 2021, 4 (11) e202101034; DOI: 10.26508/lsa.202101034
In this Issue
Volume 4, No. 11
November 2021
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