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Structure of the helicase core of Werner helicase, a key target in microsatellite instability cancers

Joseph A Newman, Angeline E Gavard, Simone Lieb, Madhwesh C Ravichandran, Katja Hauer, Patrick Werni, Leonhard Geist, Jark Böttcher, John R Engen, Klaus Rumpel, Matthias Samwer, Mark Petronczki, Opher Gileadi  Correspondence email
Published 16 November 2020. DOI: 10.26508/lsa.202000795

Article Information

vol. 4 no. 1 e202000795
DOI 
https://doi.org/10.26508/lsa.202000795
PubMed 
33199508
Published By 
Life Science Alliance
Online ISSN 
2575-1077
History 
  • Received May 26, 2020
  • Revision received October 28, 2020
  • Accepted October 28, 2020
  • Published online November 16, 2020.
Copyright & Usage 
© 2020 Newman et al. This article is available under a Creative Commons License (Attribution 4.0 International, as described at https://creativecommons.org/licenses/by/4.0/).

Author Information

  1. Joseph A Newman1,
  2. Angeline E Gavard1,
  3. Simone Lieb2,
  4. Madhwesh C Ravichandran2,
  5. Katja Hauer2,
  6. Patrick Werni2,
  7. Leonhard Geist2,
  8. Jark Böttcher2,
  9. John R Engen3,
  10. Klaus Rumpel2,
  11. Matthias Samwer2,
  12. Mark Petronczki2 and
  13. Opher Gileadi1⇑
  1. 1Structural Genomics Consortium, University of Oxford, Oxford, UK
  2. 2Boehringer Ingelheim RCV GmbH & Co KG, Vienna, Austria
  3. 3Department of Chemistry and Chemical Biology, Northeastern University, Boston, MA, USA
  1. Correspondence: opher.gileadi{at}cmd.ox.ac.uk
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Crystal structure of Werner syndrome helicase core domain
Joseph A Newman, Angeline E Gavard, Simone Lieb, Madhwesh C Ravichandran, Katja Hauer, Patrick Werni, Leonhard Geist, Jark Böttcher, John R Engen, Klaus Rumpel, Matthias Samwer, Mark Petronczki, Opher Gileadi
Life Science Alliance Nov 2020, 4 (1) e202000795; DOI: 10.26508/lsa.202000795
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