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BRD2 regulation of sigma-2 receptor upon cholesterol deprivation

Hongtao Shen, Jing Li, Xiujie Xie, View ORCID ProfileHuan Yang, Mengxue Zhang, Bowen Wang, K Craig Kent, Jorge Plutzky, View ORCID ProfileLian-Wang Guo
Hongtao Shen
1Department of Surgery, School of Medicine, University of Virginia, Charlottesville, VA, USA
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Jing Li
1Department of Surgery, School of Medicine, University of Virginia, Charlottesville, VA, USA
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Xiujie Xie
1Department of Surgery, School of Medicine, University of Virginia, Charlottesville, VA, USA
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Huan Yang
1Department of Surgery, School of Medicine, University of Virginia, Charlottesville, VA, USA
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Mengxue Zhang
1Department of Surgery, School of Medicine, University of Virginia, Charlottesville, VA, USA
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Bowen Wang
1Department of Surgery, School of Medicine, University of Virginia, Charlottesville, VA, USA
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K Craig Kent
1Department of Surgery, School of Medicine, University of Virginia, Charlottesville, VA, USA
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Jorge Plutzky
2Cardiovascular Division, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USA
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Lian-Wang Guo
1Department of Surgery, School of Medicine, University of Virginia, Charlottesville, VA, USA
3Robert M. Berne Cardiovascular Research Center, University of Virginia, Charlottesville, VA, USA
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  • ORCID record for Lian-Wang Guo
Published 24 November 2020. DOI: 10.26508/lsa.201900540
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Article Information

vol. 4 no. 1 e201900540
DOI 
https://doi.org/10.26508/lsa.201900540
PubMed 
33234676

Published By 
Life Science Alliance
Online ISSN 
2575-1077
History 
  • Received September 4, 2019
  • Revision received November 10, 2020
  • Accepted November 11, 2020
  • Published online November 24, 2020.

Copyright & Usage 
© 2020 Shen et al. This article is available under a Creative Commons License (Attribution 4.0 International, as described at https://creativecommons.org/licenses/by/4.0/).

Author Information

  1. Hongtao Shen1,*,
  2. Jing Li1,*,
  3. Xiujie Xie1,
  4. Huan Yang1,
  5. Mengxue Zhang1,
  6. Bowen Wang1,
  7. K Craig Kent1,
  8. Jorge Plutzky2 and
  9. Lian-Wang Guo1,3
  1. 1Department of Surgery, School of Medicine, University of Virginia, Charlottesville, VA, USA
  2. 2Cardiovascular Division, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USA
  3. 3Robert M. Berne Cardiovascular Research Center, University of Virginia, Charlottesville, VA, USA
  1. Correspondence: lg8zr{at}virginia.edu
  1. ↵* Hongtao Shen and Jing Li contributed equally to this work

View Full Text

Funding

  • NIH R01

    HL133665 and EY029809
    L-W Guo
  • NIH R01

    HL143469 and HL129785
    KC Kent, L-W Guo
  • American Heart Association pre-doctoral award

    17PRE33670865
    MX Zhang
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BRD2/SREBP2 control sigma-2 receptor levels
Hongtao Shen, Jing Li, Xiujie Xie, Huan Yang, Mengxue Zhang, Bowen Wang, K Craig Kent, Jorge Plutzky, Lian-Wang Guo
Life Science Alliance Nov 2020, 4 (1) e201900540; DOI: 10.26508/lsa.201900540

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BRD2/SREBP2 control sigma-2 receptor levels
Hongtao Shen, Jing Li, Xiujie Xie, Huan Yang, Mengxue Zhang, Bowen Wang, K Craig Kent, Jorge Plutzky, Lian-Wang Guo
Life Science Alliance Nov 2020, 4 (1) e201900540; DOI: 10.26508/lsa.201900540
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Volume 4, No. 1
January 2021
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