Mitochondrial spongiotic brain disease: astrocytic stress and harmful rapamycin and ketosis effect

Olesia Ignatenko; Joni Nikkanen; Alexander Kononov; Nicola Zamboni; Gulayse Ince-Dunn; Anu Suomalainen

doi:10.26508/lsa.202000797

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Mitochondrial spongiotic brain disease: astrocytic stress and harmful rapamycin and ketosis effect

View ORCID ProfileOlesia Ignatenko, View ORCID ProfileJoni Nikkanen, View ORCID ProfileAlexander Kononov, Nicola Zamboni, View ORCID ProfileGulayse Ince-Dunn, View ORCID ProfileAnu Suomalainen Correspondence email

Olesia Ignatenko

1Stem Cells and Metabolism Research Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland

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Joni Nikkanen

2Cardiovascular Research Institute, University of California, San Francisco, CA, USA

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Alexander Kononov

3Cancer Research UK, University of Manchester, Manchester, UK

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Nicola Zamboni

4Department of Biology, Institute of Molecular Systems Biology, Eidgenössische Technische Hochschule (ETH) Zurich, Zurich, Switzerland

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Gulayse Ince-Dunn

1Stem Cells and Metabolism Research Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland

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Anu Suomalainen

1Stem Cells and Metabolism Research Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland

5Neuroscience Center, University of Helsinki, Helsinki, Finland

6HUSlab, Helsinki University Hospital, Helsinki, Finland

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For correspondence: anu.wartiovaara@helsinki.fi

Published 31 July 2020. DOI: 10.26508/lsa.202000797

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Treating astrocyte mtDNA depletion

Olesia Ignatenko, Joni Nikkanen, Alexander Kononov, Nicola Zamboni, Gulayse Ince-Dunn, Anu Suomalainen

Life Science Alliance Jul 2020, 3 (9) e202000797; DOI: 10.26508/lsa.202000797

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Treating astrocyte mtDNA depletion

Olesia Ignatenko, Joni Nikkanen, Alexander Kononov, Nicola Zamboni, Gulayse Ince-Dunn, Anu Suomalainen

Life Science Alliance Jul 2020, 3 (9) e202000797; DOI: 10.26508/lsa.202000797

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