STAG1 vulnerabilities for exploiting cohesin synthetic lethality in STAG2-deficient cancers

Petra van der Lelij; Joseph A Newman; Simone Lieb; Julian Jude; Vittorio Katis; Thomas Hoffmann; Matthias Hinterndorfer; Gerd Bader; Norbert Kraut; Mark A Pearson; Jan-Michael Peters; Johannes Zuber; Opher Gileadi; Mark Petronczki

doi:10.26508/lsa.202000725

Research Article

Open Access

STAG1 vulnerabilities for exploiting cohesin synthetic lethality in STAG2-deficient cancers

View ORCID ProfilePetra van der Lelij, Joseph A Newman, Simone Lieb, Julian Jude, Vittorio Katis, Thomas Hoffmann, Matthias Hinterndorfer, Gerd Bader, Norbert Kraut, Mark A Pearson, Jan-Michael Peters, Johannes Zuber Correspondence email, Opher Gileadi Correspondence email, View ORCID ProfileMark Petronczki Correspondence email

Petra van der Lelij

1Research Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), Vienna, Austria

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
ORCID record for Petra van der Lelij

Joseph A Newman

2Structural Genomics Consortium, University of Oxford, Oxford, UK

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Simone Lieb

3Boehringer Ingelheim Regional Center Vienna (RCV) GmbH & Co KG, Vienna, Austria

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Julian Jude

1Research Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), Vienna, Austria

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Vittorio Katis

2Structural Genomics Consortium, University of Oxford, Oxford, UK

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Thomas Hoffmann

1Research Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), Vienna, Austria

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Matthias Hinterndorfer

1Research Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), Vienna, Austria

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Gerd Bader

3Boehringer Ingelheim Regional Center Vienna (RCV) GmbH & Co KG, Vienna, Austria

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Norbert Kraut

3Boehringer Ingelheim Regional Center Vienna (RCV) GmbH & Co KG, Vienna, Austria

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Mark A Pearson

3Boehringer Ingelheim Regional Center Vienna (RCV) GmbH & Co KG, Vienna, Austria

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Jan-Michael Peters

1Research Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), Vienna, Austria

4Medical University of Vienna, VBC, Vienna, Austria

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Johannes Zuber

1Research Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), Vienna, Austria

4Medical University of Vienna, VBC, Vienna, Austria

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
For correspondence: johannes.zuber@imp.ac.at

Opher Gileadi

2Structural Genomics Consortium, University of Oxford, Oxford, UK

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
For correspondence: opher.gileadi@sgc.ox.ac.uk

Mark Petronczki

3Boehringer Ingelheim Regional Center Vienna (RCV) GmbH & Co KG, Vienna, Austria

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
ORCID record for Mark Petronczki
For correspondence: mark_paul.petronczki@boehringer-ingelheim.com

Published 28 May 2020. DOI: 10.26508/lsa.202000725

Article
Figures & Data
Info
Metrics
Reviewer Comments
PDF

You are using an old browser, click here to download PDF

PDF Container

PreviousNext

Download PDF

Email Article

Thank you for your interest in spreading the word on Life Science Alliance.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Your Email *

Your Name *

Send To *

Enter multiple addresses on separate lines or separate them with commas.

You are going to email the following STAG1 vulnerabilities for exploiting cohesin synthetic lethality in STAG2-deficient cancers

Message Subject (Your Name) has sent you a message from Life Science Alliance

Message Body (Your Name) thought you would like to see the Life Science Alliance web site.

Your Personal Message

CAPTCHA

This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.

Citation Tools

Exploiting cohesin synthetic lethality

Petra van der Lelij, Joseph A Newman, Simone Lieb, Julian Jude, Vittorio Katis, Thomas Hoffmann, Matthias Hinterndorfer, Gerd Bader, Norbert Kraut, Mark A Pearson, Jan-Michael Peters, Johannes Zuber, Opher Gileadi, Mark Petronczki

Life Science Alliance May 2020, 3 (7) e202000725; DOI: 10.26508/lsa.202000725

Citation Manager Formats

BibTeX
Bookends
EasyBib
EndNote (tagged)
EndNote 8 (xml)
Medlars
Mendeley
Papers
RefWorks Tagged
Ref Manager
RIS
Zotero

Exploiting cohesin synthetic lethality

Life Science Alliance May 2020, 3 (7) e202000725; DOI: 10.26508/lsa.202000725

Share This Article:

Tweet Widget
Facebook Like

In this Issue

Volume 3, No. 7

July 2020

Table of Contents
Cover (PDF)
About the Cover
Masthead (PDF)

Jump to section

Article
Figures & Data
Info
Metrics
Reviewer Comments
PDF

Subjects

Cancer
Cell Biology
Structural Biology

No related articles found.

Cited By...

Paralogous synthetic lethality underlies genetic dependencies of the cancer-mutated gene STAG2

Google Scholar

Main menu

User menu

Search

STAG1 vulnerabilities for exploiting cohesin synthetic lethality in STAG2-deficient cancers

Citation Manager Formats

In this Issue

Subjects

Related Articles

Cited By...

More in this TOC Section

Similar Articles

Content

For Authors

Other Services

More Information