Research Article

Open Access
Caspase-1 interdomain linker cleavage is required for pyroptosis
Daniel P Ball, Cornelius Y Taabazuing, Andrew R Griswold, Elizabeth L Orth, Sahana D Rao, Ilana B Kotliar, Lauren E Vostal, Darren C Johnson, View ORCID ProfileDaniel A Bachovchin Correspondence email
Daniel P Ball
1Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA
Cornelius Y Taabazuing
1Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA
Andrew R Griswold
2Weill Cornell/Rockefeller/Sloan Kettering Tri-Institutional MD-PhD Program, New York, NY, USA
Elizabeth L Orth
3Tri-Institutional PhD Program in Chemical Biology, Memorial Sloan Kettering Cancer Center, New York, NY, USA
Sahana D Rao
3Tri-Institutional PhD Program in Chemical Biology, Memorial Sloan Kettering Cancer Center, New York, NY, USA
Ilana B Kotliar
3Tri-Institutional PhD Program in Chemical Biology, Memorial Sloan Kettering Cancer Center, New York, NY, USA
Lauren E Vostal
3Tri-Institutional PhD Program in Chemical Biology, Memorial Sloan Kettering Cancer Center, New York, NY, USA
Darren C Johnson
3Tri-Institutional PhD Program in Chemical Biology, Memorial Sloan Kettering Cancer Center, New York, NY, USA
Daniel A Bachovchin
1Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA
3Tri-Institutional PhD Program in Chemical Biology, Memorial Sloan Kettering Cancer Center, New York, NY, USA
4Pharmacology Program of the Weill Cornell Graduate School of Medical Sciences, Memorial Sloan Kettering Cancer Center, New York, NY, USA
Published 12 February 2020. DOI: 10.26508/lsa.202000664
Caspase-1 activation requires autoproteolysis
Daniel P Ball, Cornelius Y Taabazuing, Andrew R Griswold, Elizabeth L Orth, Sahana D Rao, Ilana B Kotliar, Lauren E Vostal, Darren C Johnson, Daniel A Bachovchin
Life Science Alliance Feb 2020, 3 (3) e202000664; DOI: 10.26508/lsa.202000664
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Volume 3, No. 3
March 2020
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