Transglutaminase 2 mediates hypoxia-induced selective mRNA translation via polyamination of 4EBPs

Sung-Yup Cho; Seungun Lee; Jeonghun Yeom; Hyo-Jun Kim; Jin-Haeng Lee; Ji-Woong Shin; Mee-ae Kwon; Ki Baek Lee; Eui Man Jeong; Hee Sung Ahn; Dong-Myung Shin; Kyunggon Kim; In-Gyu Kim

doi:10.26508/lsa.201900565

Research Article

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Transglutaminase 2 mediates hypoxia-induced selective mRNA translation via polyamination of 4EBPs

View ORCID ProfileSung-Yup Cho Correspondence email, Seungun Lee, Jeonghun Yeom, Hyo-Jun Kim, Jin-Haeng Lee, Ji-Woong Shin, Mee-ae Kwon, Ki Baek Lee, Eui Man Jeong, View ORCID ProfileHee Sung Ahn, Dong-Myung Shin, Kyunggon Kim Correspondence email, View ORCID ProfileIn-Gyu Kim Correspondence email

Sung-Yup Cho

1Department of Biochemistry and Molecular Biology, Seoul National University College of Medicine, Seoul, Korea

2Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, Korea

3Cancer Research Institute, Seoul National University College of Medicine, Seoul, Korea

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ORCID record for Sung-Yup Cho
For correspondence: csybio@snu.ac.kr

Seungun Lee

4Department of Biomedical Sciences, University of Ulsan College of Medicine, Seoul, Korea

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Jeonghun Yeom

5Department of Convergence Medicine, Asan Medical Center, Seoul, Korea

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Hyo-Jun Kim

1Department of Biochemistry and Molecular Biology, Seoul National University College of Medicine, Seoul, Korea

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Jin-Haeng Lee

1Department of Biochemistry and Molecular Biology, Seoul National University College of Medicine, Seoul, Korea

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Ji-Woong Shin

1Department of Biochemistry and Molecular Biology, Seoul National University College of Medicine, Seoul, Korea

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Mee-ae Kwon

1Department of Biochemistry and Molecular Biology, Seoul National University College of Medicine, Seoul, Korea

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Ki Baek Lee

1Department of Biochemistry and Molecular Biology, Seoul National University College of Medicine, Seoul, Korea

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Eui Man Jeong

1Department of Biochemistry and Molecular Biology, Seoul National University College of Medicine, Seoul, Korea

6Institute of Human-Environment Interface Biology, Seoul National University College of Medicine, Seoul, Korea

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Hee Sung Ahn

5Department of Convergence Medicine, Asan Medical Center, Seoul, Korea

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ORCID record for Hee Sung Ahn

Dong-Myung Shin

4Department of Biomedical Sciences, University of Ulsan College of Medicine, Seoul, Korea

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Kyunggon Kim

4Department of Biomedical Sciences, University of Ulsan College of Medicine, Seoul, Korea

5Department of Convergence Medicine, Asan Medical Center, Seoul, Korea

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For correspondence: kimkyunggon@gmail.com

In-Gyu Kim

1Department of Biochemistry and Molecular Biology, Seoul National University College of Medicine, Seoul, Korea

6Institute of Human-Environment Interface Biology, Seoul National University College of Medicine, Seoul, Korea

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ORCID record for In-Gyu Kim
For correspondence: igkim@plaza.snu.ac.kr

Published 19 February 2020. DOI: 10.26508/lsa.201900565

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Selective translation by TG2 in hypoxia

Sung-Yup Cho, Seungun Lee, Jeonghun Yeom, Hyo-Jun Kim, Jin-Haeng Lee, Ji-Woong Shin, Mee-ae Kwon, Ki Baek Lee, Eui Man Jeong, Hee Sung Ahn, Dong-Myung Shin, Kyunggon Kim, In-Gyu Kim

Life Science Alliance Feb 2020, 3 (3) e201900565; DOI: 10.26508/lsa.201900565

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Selective translation by TG2 in hypoxia

Sung-Yup Cho, Seungun Lee, Jeonghun Yeom, Hyo-Jun Kim, Jin-Haeng Lee, Ji-Woong Shin, Mee-ae Kwon, Ki Baek Lee, Eui Man Jeong, Hee Sung Ahn, Dong-Myung Shin, Kyunggon Kim, In-Gyu Kim

Life Science Alliance Feb 2020, 3 (3) e201900565; DOI: 10.26508/lsa.201900565

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