Spastin recovery in hereditary spastic paraplegia by preventing neddylation-dependent degradation

Francesca Sardina; Alessandra Pisciottani; Manuela Ferrara; Davide Valente; Marialuisa Casella; Marco Crescenzi; Angelo Peschiaroli; Carlo Casali; Silvia Soddu; Andrew J Grierson; Cinzia Rinaldo

doi:10.26508/lsa.202000799

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Spastin recovery in hereditary spastic paraplegia by preventing neddylation-dependent degradation

View ORCID ProfileFrancesca Sardina Correspondence email, Alessandra Pisciottani, Manuela Ferrara, View ORCID ProfileDavide Valente, Marialuisa Casella, Marco Crescenzi, Angelo Peschiaroli, Carlo Casali, Silvia Soddu, Andrew J Grierson, View ORCID ProfileCinzia Rinaldo Correspondence email

Francesca Sardina

1Institute of Molecular Biology and Pathology (IBPM), National Research Council (CNR), c/o Sapienza University, Rome, Italy

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ORCID record for Francesca Sardina
For correspondence: francesca.sardina3@gmail.com

Alessandra Pisciottani

1Institute of Molecular Biology and Pathology (IBPM), National Research Council (CNR), c/o Sapienza University, Rome, Italy

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Manuela Ferrara

1Institute of Molecular Biology and Pathology (IBPM), National Research Council (CNR), c/o Sapienza University, Rome, Italy

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Davide Valente

1Institute of Molecular Biology and Pathology (IBPM), National Research Council (CNR), c/o Sapienza University, Rome, Italy

5Unit of Cellular Networks and Molecular Therapeutic Targets, IRCCS–Regina Elena National Cancer Institute, Rome, Italy

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Marialuisa Casella

2Core Facilities, Italian National Institute of Health, Rome, Italy

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Marco Crescenzi

2Core Facilities, Italian National Institute of Health, Rome, Italy

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Angelo Peschiaroli

3Institute of Translational Pharmacology, CNR, Rome, Italy

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Carlo Casali

4Department of Medico-Surgical Sciences and Biotechnologies, University of Rome Sapienza, Latina, Italy

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Silvia Soddu

5Unit of Cellular Networks and Molecular Therapeutic Targets, IRCCS–Regina Elena National Cancer Institute, Rome, Italy

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Andrew J Grierson

6Sheffield Institute for Translational Neuroscience, University of Sheffield, Sheffield, UK

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Cinzia Rinaldo

1Institute of Molecular Biology and Pathology (IBPM), National Research Council (CNR), c/o Sapienza University, Rome, Italy

5Unit of Cellular Networks and Molecular Therapeutic Targets, IRCCS–Regina Elena National Cancer Institute, Rome, Italy

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ORCID record for Cinzia Rinaldo
For correspondence: cinzia.rinaldo@uniroma1.it

Published 26 October 2020. DOI: 10.26508/lsa.202000799

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Regulation of spastin level by degradation

Francesca Sardina, Alessandra Pisciottani, Manuela Ferrara, Davide Valente, Marialuisa Casella, Marco Crescenzi, Angelo Peschiaroli, Carlo Casali, Silvia Soddu, Andrew J Grierson, Cinzia Rinaldo

Life Science Alliance Oct 2020, 3 (12) e202000799; DOI: 10.26508/lsa.202000799

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Regulation of spastin level by degradation

Francesca Sardina, Alessandra Pisciottani, Manuela Ferrara, Davide Valente, Marialuisa Casella, Marco Crescenzi, Angelo Peschiaroli, Carlo Casali, Silvia Soddu, Andrew J Grierson, Cinzia Rinaldo

Life Science Alliance Oct 2020, 3 (12) e202000799; DOI: 10.26508/lsa.202000799

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