Multiplexed chemogenetics in astrocytes and motoneurons restore blood–spinal cord barrier in ALS

Najwa Ouali Alami; Linyun Tang; Diana Wiesner; Barbara Commisso; David Bayer; Jochen Weishaupt; Luc Dupuis; Phillip Wong; Bernd Baumann; Thomas Wirth; Tobias M Boeckers; Deniz Yilmazer-Hanke; Albert Ludolph; Francesco Roselli

doi:10.26508/lsa.201900571

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Multiplexed chemogenetics in astrocytes and motoneurons restore blood–spinal cord barrier in ALS

View ORCID ProfileNajwa Ouali Alami, Linyun Tang, Diana Wiesner, Barbara Commisso, David Bayer, Jochen Weishaupt, Luc Dupuis, Phillip Wong, Bernd Baumann, Thomas Wirth, Tobias M Boeckers, View ORCID ProfileDeniz Yilmazer-Hanke, Albert Ludolph, View ORCID ProfileFrancesco Roselli Correspondence email

Najwa Ouali Alami

1Department of Neurology, Ulm University, Ulm, Germany

2International Graduate School in Molecular Medicine Ulm, Ulm, Germany

3Department of Neurology, Clinical Neuroanatomy, Ulm University, Ulm, Germany

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ORCID record for Najwa Ouali Alami

Linyun Tang

1Department of Neurology, Ulm University, Ulm, Germany

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Diana Wiesner

1Department of Neurology, Ulm University, Ulm, Germany

4German Center for Neurodegenerative Diseases (DZNE), Ulm, Germany

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Barbara Commisso

1Department of Neurology, Ulm University, Ulm, Germany

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David Bayer

1Department of Neurology, Ulm University, Ulm, Germany

5CEMMA Graduate School, Ulm University, Ulm, Germany

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Jochen Weishaupt

1Department of Neurology, Ulm University, Ulm, Germany

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Luc Dupuis

6Inserm U1118, Mécanismes Centraux et Périphériques de la Neurodégénérescence; Université de Strasbourg, Faculté de Médecine, Strasbourg, France

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Phillip Wong

7Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA

8Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD, USA

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Bernd Baumann

9Institute of Physiological Chemistry, Ulm University, Ulm, Germany

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Thomas Wirth

9Institute of Physiological Chemistry, Ulm University, Ulm, Germany

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Tobias M Boeckers

4German Center for Neurodegenerative Diseases (DZNE), Ulm, Germany

10Department of Anatomy and Cell Biology, Ulm University, Ulm, Germany

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Deniz Yilmazer-Hanke

3Department of Neurology, Clinical Neuroanatomy, Ulm University, Ulm, Germany

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Albert Ludolph

1Department of Neurology, Ulm University, Ulm, Germany

4German Center for Neurodegenerative Diseases (DZNE), Ulm, Germany

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Francesco Roselli

1Department of Neurology, Ulm University, Ulm, Germany

4German Center for Neurodegenerative Diseases (DZNE), Ulm, Germany

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ORCID record for Francesco Roselli
For correspondence: francesco.roselli@uni-ulm.de

Published 8 September 2020. DOI: 10.26508/lsa.201900571

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Chemogenetics restore BSCB in ALS

Najwa Ouali Alami, Linyun Tang, Diana Wiesner, Barbara Commisso, David Bayer, Jochen Weishaupt, Luc Dupuis, Phillip Wong, Bernd Baumann, Thomas Wirth, Tobias M Boeckers, Deniz Yilmazer-Hanke, Albert Ludolph, Francesco Roselli

Life Science Alliance Sep 2020, 3 (11) e201900571; DOI: 10.26508/lsa.201900571

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Chemogenetics restore BSCB in ALS

Life Science Alliance Sep 2020, 3 (11) e201900571; DOI: 10.26508/lsa.201900571

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