Multiplexed chemogenetics in astrocytes and motoneurons restore blood–spinal cord barrier in ALS

Najwa Ouali Alami; Linyun Tang; Diana Wiesner; Barbara Commisso; David Bayer; Jochen Weishaupt; Luc Dupuis; Phillip Wong; Bernd Baumann; Thomas Wirth; Tobias M Boeckers; Deniz Yilmazer-Hanke; Albert Ludolph; Francesco Roselli

doi:10.26508/lsa.201900571

Research Article

Open Access

Multiplexed chemogenetics in astrocytes and motoneurons restore blood–spinal cord barrier in ALS

View ORCID ProfileNajwa Ouali Alami, Linyun Tang, Diana Wiesner, Barbara Commisso, David Bayer, Jochen Weishaupt, Luc Dupuis, Phillip Wong, Bernd Baumann, Thomas Wirth, Tobias M Boeckers, View ORCID ProfileDeniz Yilmazer-Hanke, Albert Ludolph, View ORCID ProfileFrancesco Roselli Correspondence email

Najwa Ouali Alami

1Department of Neurology, Ulm University, Ulm, Germany

2International Graduate School in Molecular Medicine Ulm, Ulm, Germany

3Department of Neurology, Clinical Neuroanatomy, Ulm University, Ulm, Germany

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
ORCID record for Najwa Ouali Alami

Linyun Tang

1Department of Neurology, Ulm University, Ulm, Germany

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Diana Wiesner

1Department of Neurology, Ulm University, Ulm, Germany

4German Center for Neurodegenerative Diseases (DZNE), Ulm, Germany

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Barbara Commisso

1Department of Neurology, Ulm University, Ulm, Germany

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

David Bayer

1Department of Neurology, Ulm University, Ulm, Germany

5CEMMA Graduate School, Ulm University, Ulm, Germany

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Jochen Weishaupt

1Department of Neurology, Ulm University, Ulm, Germany

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Luc Dupuis

6Inserm U1118, Mécanismes Centraux et Périphériques de la Neurodégénérescence; Université de Strasbourg, Faculté de Médecine, Strasbourg, France

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Phillip Wong

7Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA

8Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD, USA

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Bernd Baumann

9Institute of Physiological Chemistry, Ulm University, Ulm, Germany

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Thomas Wirth

9Institute of Physiological Chemistry, Ulm University, Ulm, Germany

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Tobias M Boeckers

4German Center for Neurodegenerative Diseases (DZNE), Ulm, Germany

10Department of Anatomy and Cell Biology, Ulm University, Ulm, Germany

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Deniz Yilmazer-Hanke

3Department of Neurology, Clinical Neuroanatomy, Ulm University, Ulm, Germany

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
ORCID record for Deniz Yilmazer-Hanke

Albert Ludolph

1Department of Neurology, Ulm University, Ulm, Germany

4German Center for Neurodegenerative Diseases (DZNE), Ulm, Germany

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Francesco Roselli

1Department of Neurology, Ulm University, Ulm, Germany

4German Center for Neurodegenerative Diseases (DZNE), Ulm, Germany

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
ORCID record for Francesco Roselli
For correspondence: francesco.roselli@uni-ulm.de

Published 8 September 2020. DOI: 10.26508/lsa.201900571

Article
Figures & Data
Info
Metrics
Reviewer Comments
PDF

Statistics from Altmetric.com

Article usage

Article usage: September 2020 to September 2020

	Abstract	Full	Pdf
Sep 2020	28	298	146

PreviousNext

Download PDF

Article Alerts

User Name *

Password *

Email *

Email Article

Thank you for your interest in spreading the word on Life Science Alliance.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Your Email *

Your Name *

Send To *

Enter multiple addresses on separate lines or separate them with commas.

You are going to email the following Multiplexed chemogenetics in astrocytes and motoneurons restore blood–spinal cord barrier in ALS

Message Subject (Your Name) has sent you a message from Life Science Alliance

Message Body (Your Name) thought you would like to see the Life Science Alliance web site.

Your Personal Message

CAPTCHA

This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.

Citation Tools

Chemogenetics restore BSCB in ALS

Najwa Ouali Alami, Linyun Tang, Diana Wiesner, Barbara Commisso, David Bayer, Jochen Weishaupt, Luc Dupuis, Phillip Wong, Bernd Baumann, Thomas Wirth, Tobias M Boeckers, Deniz Yilmazer-Hanke, Albert Ludolph, Francesco Roselli

Life Science Alliance Sep 2020, 3 (11) e201900571; DOI: 10.26508/lsa.201900571