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Genome-wide R-loop analysis defines unique roles for DDX5, XRN2, and PRMT5 in DNA/RNA hybrid resolution

View ORCID ProfileOscar D Villarreal, Sofiane Y Mersaoui, Zhenbao Yu, Jean-Yves Masson, View ORCID ProfileStéphane Richard  Correspondence email
Oscar D Villarreal
1Segal Cancer Center, Lady Davis Institute for Medical Research and Gerald Bronfman Department of Oncology and Departments of Biochemistry, Human Genetics and Medicine, McGill University, Montréal, Canada
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  • ORCID record for Oscar D Villarreal
Sofiane Y Mersaoui
1Segal Cancer Center, Lady Davis Institute for Medical Research and Gerald Bronfman Department of Oncology and Departments of Biochemistry, Human Genetics and Medicine, McGill University, Montréal, Canada
2Genome Stability Laboratory, Centre Hospitalier Universitaire de Québec Research Center, Oncology Axis; Department of Molecular Biology, Medical Biochemistry and Pathology; Laval University Cancer Research Center, Québec City, Canada
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Zhenbao Yu
1Segal Cancer Center, Lady Davis Institute for Medical Research and Gerald Bronfman Department of Oncology and Departments of Biochemistry, Human Genetics and Medicine, McGill University, Montréal, Canada
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Jean-Yves Masson
2Genome Stability Laboratory, Centre Hospitalier Universitaire de Québec Research Center, Oncology Axis; Department of Molecular Biology, Medical Biochemistry and Pathology; Laval University Cancer Research Center, Québec City, Canada
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Stéphane Richard
1Segal Cancer Center, Lady Davis Institute for Medical Research and Gerald Bronfman Department of Oncology and Departments of Biochemistry, Human Genetics and Medicine, McGill University, Montréal, Canada
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  • ORCID record for Stéphane Richard
  • For correspondence: stephane.richard@mcgill.ca
Published 3 August 2020. DOI: 10.26508/lsa.202000762
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Genome-wide R-loop analysis defines unique roles for DDX5, XRN2, and PRMT5 in DNA/RNA hybrid resolution
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DRIP-seq analysis of siDDX5, siXRN2 and siPRMT5 U2OS cells
Oscar D Villarreal, Sofiane Y Mersaoui, Zhenbao Yu, Jean-Yves Masson, Stéphane Richard
Life Science Alliance Aug 2020, 3 (10) e202000762; DOI: 10.26508/lsa.202000762

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DRIP-seq analysis of siDDX5, siXRN2 and siPRMT5 U2OS cells
Oscar D Villarreal, Sofiane Y Mersaoui, Zhenbao Yu, Jean-Yves Masson, Stéphane Richard
Life Science Alliance Aug 2020, 3 (10) e202000762; DOI: 10.26508/lsa.202000762
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Volume 3, No. 10
October 2020
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