Genome-wide R-loop analysis defines unique roles for DDX5, XRN2, and PRMT5 in DNA/RNA hybrid resolution

Oscar D Villarreal; Sofiane Y Mersaoui; Zhenbao Yu; Jean-Yves Masson; Stéphane Richard

doi:10.26508/lsa.202000762

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Genome-wide R-loop analysis defines unique roles for DDX5, XRN2, and PRMT5 in DNA/RNA hybrid resolution

View ORCID ProfileOscar D Villarreal, Sofiane Y Mersaoui, Zhenbao Yu, Jean-Yves Masson, View ORCID ProfileStéphane Richard Correspondence email

Oscar D Villarreal

1Segal Cancer Center, Lady Davis Institute for Medical Research and Gerald Bronfman Department of Oncology and Departments of Biochemistry, Human Genetics and Medicine, McGill University, Montréal, Canada

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ORCID record for Oscar D Villarreal

Sofiane Y Mersaoui

2Genome Stability Laboratory, Centre Hospitalier Universitaire de Québec Research Center, Oncology Axis; Department of Molecular Biology, Medical Biochemistry and Pathology; Laval University Cancer Research Center, Québec City, Canada

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Zhenbao Yu

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Jean-Yves Masson

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Stéphane Richard

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ORCID record for Stéphane Richard
For correspondence: stephane.richard@mcgill.ca

Published 3 August 2020. DOI: 10.26508/lsa.202000762

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DRIP-seq analysis of siDDX5, siXRN2 and siPRMT5 U2OS cells