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Research Article
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The RECQL helicase prevents replication fork collapse during replication stress

View ORCID ProfileBente Benedict, View ORCID ProfileMarit AE van Bueren, Frank PA van Gemert, Cor Lieftink, Sergi Guerrero Llobet, View ORCID ProfileMarcel ATM van Vugt, Roderick L Beijersbergen, View ORCID ProfileHein te Riele  Correspondence email
Bente Benedict
1Division of Tumor Biology and Immunology, The Netherlands Cancer Institute, Amsterdam, The Netherlands
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  • ORCID record for Bente Benedict
Marit AE van Bueren
1Division of Tumor Biology and Immunology, The Netherlands Cancer Institute, Amsterdam, The Netherlands
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  • ORCID record for Marit AE van Bueren
Frank PA van Gemert
1Division of Tumor Biology and Immunology, The Netherlands Cancer Institute, Amsterdam, The Netherlands
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Cor Lieftink
2Division of Molecular Carcinogenesis, Robotics and Screening Center, The Netherlands Cancer Institute, Amsterdam, The Netherlands
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Sergi Guerrero Llobet
3Department of Medical Oncology, Cancer Research Center Groningen, University Medical Center Groningen, Groningen, The Netherlands
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Marcel ATM van Vugt
3Department of Medical Oncology, Cancer Research Center Groningen, University Medical Center Groningen, Groningen, The Netherlands
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  • ORCID record for Marcel ATM van Vugt
Roderick L Beijersbergen
2Division of Molecular Carcinogenesis, Robotics and Screening Center, The Netherlands Cancer Institute, Amsterdam, The Netherlands
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Hein te Riele
1Division of Tumor Biology and Immunology, The Netherlands Cancer Institute, Amsterdam, The Netherlands
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  • ORCID record for Hein te Riele
  • For correspondence: h.t.riele@nki.nl
Published 20 August 2020. DOI: 10.26508/lsa.202000668
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Article Information

vol. 3 no. 10 e202000668
DOI 
https://doi.org/10.26508/lsa.202000668
PubMed 
32820027

Published By 
Life Science Alliance
Online ISSN 
2575-1077
History 
  • Received February 3, 2020
  • Revision received August 11, 2020
  • Accepted August 12, 2020
  • Published online August 20, 2020.

Copyright & Usage 
© 2020 Benedict et al. This article is available under a Creative Commons License (Attribution 4.0 International, as described at https://creativecommons.org/licenses/by/4.0/).

Author Information

  1. Bente Benedict1,
  2. Marit AE van Bueren1,*,
  3. Frank PA van Gemert1,*,
  4. Cor Lieftink2,
  5. Sergi Guerrero Llobet3,
  6. Marcel ATM van Vugt3,
  7. Roderick L Beijersbergen2 and
  8. Hein te Riele1⇑
  1. 1Division of Tumor Biology and Immunology, The Netherlands Cancer Institute, Amsterdam, The Netherlands
  2. 2Division of Molecular Carcinogenesis, Robotics and Screening Center, The Netherlands Cancer Institute, Amsterdam, The Netherlands
  3. 3Department of Medical Oncology, Cancer Research Center Groningen, University Medical Center Groningen, Groningen, The Netherlands
  1. Correspondence: h.t.riele{at}nki.nl
  1. ↵* Marit AE van Bueren and Frank PA van Gemert contributed equally to this work

View Full Text

Funding

  • Dutch Cancer Society

    NKI 2014-6702 and 11074
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RECQL is essential during replication stress
Bente Benedict, Marit AE van Bueren, Frank PA van Gemert, Cor Lieftink, Sergi Guerrero Llobet, Marcel ATM van Vugt, Roderick L Beijersbergen, Hein te Riele
Life Science Alliance Aug 2020, 3 (10) e202000668; DOI: 10.26508/lsa.202000668

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RECQL is essential during replication stress
Bente Benedict, Marit AE van Bueren, Frank PA van Gemert, Cor Lieftink, Sergi Guerrero Llobet, Marcel ATM van Vugt, Roderick L Beijersbergen, Hein te Riele
Life Science Alliance Aug 2020, 3 (10) e202000668; DOI: 10.26508/lsa.202000668
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Volume 3, No. 10
October 2020
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