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Research Article
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GRP78 regulates CD44v membrane homeostasis and cell spreading in tamoxifen-resistant breast cancer

Chun-Chih Tseng, View ORCID ProfileRamunas Stanciauskas, Pu Zhang, Dennis Woo, Kaijin Wu, Kevin Kelly, Parkash S Gill, Min Yu, Fabien Pinaud, View ORCID ProfileAmy S Lee  Correspondence email
Chun-Chih Tseng
1Department of Biochemistry and Molecular Medicine, University of Southern California, Los Angeles, CA, USA
8University of Southern California Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA, USA
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Ramunas Stanciauskas
2Department of Biological Sciences, University of Southern California, Los Angeles, CA, USA
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  • ORCID record for Ramunas Stanciauskas
Pu Zhang
6Department of Molecular Microbiology and Immunology, University of Southern California, Los Angeles, CA, USA
8University of Southern California Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA, USA
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Dennis Woo
8University of Southern California Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA, USA
9Department of Stem Cell Biology and Regenerative Medicine, University of Southern California, Los Angeles, CA, USA
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Kaijin Wu
5Department of Medicine/Division of Hematology, University of Southern California, Los Angeles, CA, USA
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Kevin Kelly
5Department of Medicine/Division of Hematology, University of Southern California, Los Angeles, CA, USA
8University of Southern California Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA, USA
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Parkash S Gill
7Department of Pathology, University of Southern California, Los Angeles, CA, USA
8University of Southern California Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA, USA
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Min Yu
8University of Southern California Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA, USA
9Department of Stem Cell Biology and Regenerative Medicine, University of Southern California, Los Angeles, CA, USA
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Fabien Pinaud
2Department of Biological Sciences, University of Southern California, Los Angeles, CA, USA
3Department of Chemistry, University of Southern California, Los Angeles, CA, USA
4Department of Physics and Astronomy, University of Southern California, Los Angeles, CA, USA
8University of Southern California Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA, USA
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Amy S Lee
1Department of Biochemistry and Molecular Medicine, University of Southern California, Los Angeles, CA, USA
8University of Southern California Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA, USA
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  • ORCID record for Amy S Lee
  • For correspondence: amylee@usc.edu
Published 15 August 2019. DOI: 10.26508/lsa.201900377
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Article Information

vol. 2 no. 4 e201900377
DOI 
https://doi.org/10.26508/lsa.201900377
PubMed 
31416894

Published By 
Life Science Alliance
Online ISSN 
2575-1077
History 
  • Received March 12, 2019
  • Revision received August 2, 2019
  • Accepted August 5, 2019
  • Published online August 15, 2019.

Copyright & Usage 
© 2019 Tseng et al. This article is available under a Creative Commons License (Attribution 4.0 International, as described at https://creativecommons.org/licenses/by/4.0/).

Author Information

  1. Chun-Chih Tseng1,8,
  2. Ramunas Stanciauskas2,
  3. Pu Zhang6,8,
  4. Dennis Woo8,9,
  5. Kaijin Wu5,
  6. Kevin Kelly5,8,
  7. Parkash S Gill7,8,
  8. Min Yu8,9,
  9. Fabien Pinaud2,3,4,8 and
  10. Amy S Lee1,8⇑
  1. 1Department of Biochemistry and Molecular Medicine, University of Southern California, Los Angeles, CA, USA
  2. 2Department of Biological Sciences, University of Southern California, Los Angeles, CA, USA
  3. 3Department of Chemistry, University of Southern California, Los Angeles, CA, USA
  4. 4Department of Physics and Astronomy, University of Southern California, Los Angeles, CA, USA
  5. 5Department of Medicine/Division of Hematology, University of Southern California, Los Angeles, CA, USA
  6. 6Department of Molecular Microbiology and Immunology, University of Southern California, Los Angeles, CA, USA
  7. 7Department of Pathology, University of Southern California, Los Angeles, CA, USA
  8. 8University of Southern California Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA, USA
  9. 9Department of Stem Cell Biology and Regenerative Medicine, University of Southern California, Los Angeles, CA, USA
  1. Correspondence: amylee{at}usc.edu
View Full Text

Funding

  • NIH

    P30 CA014089
  • NIH

    P30 DK048522
  • NIH

    R01 CA027607
    AS Lee
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GRP78 regulates CD44v in breast cancer
Chun-Chih Tseng, Ramunas Stanciauskas, Pu Zhang, Dennis Woo, Kaijin Wu, Kevin Kelly, Parkash S Gill, Min Yu, Fabien Pinaud, Amy S Lee
Life Science Alliance Aug 2019, 2 (4) e201900377; DOI: 10.26508/lsa.201900377

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GRP78 regulates CD44v in breast cancer
Chun-Chih Tseng, Ramunas Stanciauskas, Pu Zhang, Dennis Woo, Kaijin Wu, Kevin Kelly, Parkash S Gill, Min Yu, Fabien Pinaud, Amy S Lee
Life Science Alliance Aug 2019, 2 (4) e201900377; DOI: 10.26508/lsa.201900377
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Volume 2, No. 4
August 2019
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