MITOL deletion in the brain impairs mitochondrial structure and ER tethering leading to oxidative stress

Shun Nagashima; Keisuke Takeda; Nobuhiko Ohno; Satoshi Ishido; Motohide Aoki; Yurika Saitoh; Takumi Takada; Takeshi Tokuyama; Ayumu Sugiura; Toshifumi Fukuda; Nobuko Matsushita; Ryoko Inatome; Shigeru Yanagi

doi:10.26508/lsa.201900308

Research Article

Open Access

MITOL deletion in the brain impairs mitochondrial structure and ER tethering leading to oxidative stress

Shun Nagashima, Keisuke Takeda, Nobuhiko Ohno, Satoshi Ishido, Motohide Aoki, Yurika Saitoh, Takumi Takada, Takeshi Tokuyama, Ayumu Sugiura, Toshifumi Fukuda, Nobuko Matsushita, Ryoko Inatome, View ORCID ProfileShigeru Yanagi Correspondence email

Shun Nagashima

1Laboratory of Molecular Biochemistry, School of Life Sciences, Tokyo University of Pharmacy and Life Sciences, Hachioji, Tokyo, Japan

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Keisuke Takeda

1Laboratory of Molecular Biochemistry, School of Life Sciences, Tokyo University of Pharmacy and Life Sciences, Hachioji, Tokyo, Japan

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Nobuhiko Ohno

2Department of Anatomy, Division of Histology and Cell Biology, School of Medicine, Jichi Medical University, Shimotsuke, Japan

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Satoshi Ishido

3Department of Microbiology, Hyogo College of Medicine, Nishinomiya, Japan

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Motohide Aoki

4Laboratory of Bioanalytical and Environmental Chemistry, School of Life Sciences, Tokyo University of Pharmacy and Life Sciences, Hachioji, Tokyo, Japan

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Yurika Saitoh

5Department of Tokyo Physical Therapy, Faculty of Medical Science, Teikyo University of Science, Adachi-ku, Tokyo, Japan

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Takumi Takada

1Laboratory of Molecular Biochemistry, School of Life Sciences, Tokyo University of Pharmacy and Life Sciences, Hachioji, Tokyo, Japan

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Takeshi Tokuyama

1Laboratory of Molecular Biochemistry, School of Life Sciences, Tokyo University of Pharmacy and Life Sciences, Hachioji, Tokyo, Japan

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Ayumu Sugiura

1Laboratory of Molecular Biochemistry, School of Life Sciences, Tokyo University of Pharmacy and Life Sciences, Hachioji, Tokyo, Japan

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Toshifumi Fukuda

1Laboratory of Molecular Biochemistry, School of Life Sciences, Tokyo University of Pharmacy and Life Sciences, Hachioji, Tokyo, Japan

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Nobuko Matsushita

1Laboratory of Molecular Biochemistry, School of Life Sciences, Tokyo University of Pharmacy and Life Sciences, Hachioji, Tokyo, Japan

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Ryoko Inatome

1Laboratory of Molecular Biochemistry, School of Life Sciences, Tokyo University of Pharmacy and Life Sciences, Hachioji, Tokyo, Japan

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Shigeru Yanagi

1Laboratory of Molecular Biochemistry, School of Life Sciences, Tokyo University of Pharmacy and Life Sciences, Hachioji, Tokyo, Japan

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
ORCID record for Shigeru Yanagi
For correspondence: syanagi@ls.toyaku.ac.jp

Published 15 August 2019. DOI: 10.26508/lsa.201900308

Article
Figures & Data
Info
Metrics
Reviewer Comments
PDF

You are using an old browser, click here to download PDF

PDF Container

PreviousNext

Download PDF

Article Alerts

User Name *

Password *

Email *

Email Article

Thank you for your interest in spreading the word on Life Science Alliance.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Your Email *

Your Name *

Send To *

Enter multiple addresses on separate lines or separate them with commas.

You are going to email the following MITOL deletion in the brain impairs mitochondrial structure and ER tethering leading to oxidative stress

Message Subject (Your Name) has sent you a message from Life Science Alliance

Message Body (Your Name) thought you would like to see the Life Science Alliance web site.

Your Personal Message

CAPTCHA

This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.

Citation Tools

MITOL regulates mitochondrial dynamics in brain