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Research Article
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Inhibition of host NOX1 blocks tumor growth and enhances checkpoint inhibitor–based immunotherapy

View ORCID ProfileJimmy Stalin  Correspondence email, Sarah Garrido-Urbani, Freddy Heitz, Cédric Szyndralewiez, Stephane Jemelin, Oriana Coquoz, View ORCID ProfileCurzio Ruegg  Correspondence email, View ORCID ProfileBeat A Imhof  Correspondence email
Jimmy Stalin
1Department of Pathology and Immunology, Medical Faculty, University of Geneva, Geneva, Switzerland
2Department of Oncology, Microbiology and Immunology, Faculty of Science and Medicine, University of Fribourg, Fribourg, Switzerland
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  • ORCID record for Jimmy Stalin
  • For correspondence: jimmy.stalin@unifr.ch
Sarah Garrido-Urbani
1Department of Pathology and Immunology, Medical Faculty, University of Geneva, Geneva, Switzerland
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Freddy Heitz
3Genkyotex S.A Forum 2, Archamps Technopole, Saint-Julien-en-Genevois, France
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Cédric Szyndralewiez
3Genkyotex S.A Forum 2, Archamps Technopole, Saint-Julien-en-Genevois, France
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Stephane Jemelin
1Department of Pathology and Immunology, Medical Faculty, University of Geneva, Geneva, Switzerland
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Oriana Coquoz
2Department of Oncology, Microbiology and Immunology, Faculty of Science and Medicine, University of Fribourg, Fribourg, Switzerland
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Curzio Ruegg
2Department of Oncology, Microbiology and Immunology, Faculty of Science and Medicine, University of Fribourg, Fribourg, Switzerland
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  • ORCID record for Curzio Ruegg
  • For correspondence: curzio.ruegg@unifr.ch
Beat A Imhof
1Department of Pathology and Immunology, Medical Faculty, University of Geneva, Geneva, Switzerland
4Medicity Research Laboratory, University of Turku, Turku, Finland
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  • ORCID record for Beat A Imhof
  • For correspondence: beat.imhof@unige.ch
Published 27 June 2019. DOI: 10.26508/lsa.201800265
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Article Information

vol. 2 no. 4 e201800265
DOI 
https://doi.org/10.26508/lsa.201800265
PubMed 
31249132

Published By 
Life Science Alliance
Online ISSN 
2575-1077
History 
  • Received December 6, 2018
  • Revision received June 13, 2019
  • Accepted June 13, 2019
  • Published online June 27, 2019.

Copyright & Usage 
© 2019 Stalin et al. This article is available under a Creative Commons License (Attribution 4.0 International, as described at https://creativecommons.org/licenses/by/4.0/).

Author Information

  1. Jimmy Stalin1,2⇑,
  2. Sarah Garrido-Urbani1,
  3. Freddy Heitz3,
  4. Cédric Szyndralewiez3,
  5. Stephane Jemelin1,
  6. Oriana Coquoz2,
  7. Curzio Ruegg2,*⇑ and
  8. Beat A Imhof1,4,*⇑
  1. 1Department of Pathology and Immunology, Medical Faculty, University of Geneva, Geneva, Switzerland
  2. 2Department of Oncology, Microbiology and Immunology, Faculty of Science and Medicine, University of Fribourg, Fribourg, Switzerland
  3. 3Genkyotex S.A Forum 2, Archamps Technopole, Saint-Julien-en-Genevois, France
  4. 4Medicity Research Laboratory, University of Turku, Turku, Finland
  1. Correspondence: jimmy.stalin{at}unifr.ch
  2. curzio.ruegg{at}unifr.ch
  3. beat.imhof{at}unige.ch
  1. ↵* Curzio Ruegg and Beat A Imhof contributed equally to this work

View Full Text

Funding

  • Swiss National Science Foundation

    310030_153456
    K Henare
  • ONCOSUISSE

    KFS-2914-02-2012
    BA Imhof
  • Sigrid Juselius Foundation

    BA Imhof
  • Medic Foundation

  • Swiss National Science Foundation

    31003A_135738; 31003A_179248
    C Ruegg
  • Swiss National Science Foundation

    310030-153456
  • ONCOSUISSE

    KFS-2914-02-2012
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NOX1 inhibition suppresses tumor growth
Jimmy Stalin, Sarah Garrido-Urbani, Freddy Heitz, Cédric Szyndralewiez, Stephane Jemelin, Oriana Coquoz, Curzio Ruegg, Beat A Imhof
Life Science Alliance Jun 2019, 2 (4) e201800265; DOI: 10.26508/lsa.201800265

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NOX1 inhibition suppresses tumor growth
Jimmy Stalin, Sarah Garrido-Urbani, Freddy Heitz, Cédric Szyndralewiez, Stephane Jemelin, Oriana Coquoz, Curzio Ruegg, Beat A Imhof
Life Science Alliance Jun 2019, 2 (4) e201800265; DOI: 10.26508/lsa.201800265
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Volume 2, No. 4
August 2019
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