A molecule inducing androgen receptor degradation and selectively targeting prostate cancer cells

Serge Auvin; Harun Öztürk; Yusuf T Abaci; Gisele Mautino; Florence Meyer-Losic; Florence Jollivet; Tarig Bashir; Hugues de Thé; Umut Sahin

doi:10.26508/lsa.201800213

Research Article

Open Access

A molecule inducing androgen receptor degradation and selectively targeting prostate cancer cells

Serge Auvin, Harun Öztürk, Yusuf T Abaci, Gisele Mautino, Florence Meyer-Losic, Florence Jollivet, Tarig Bashir, Hugues de Thé, View ORCID ProfileUmut Sahin Correspondence email

Serge Auvin

1Ipsen Innovation, Les Ulis, France

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Harun Öztürk

7Department of Molecular Biology and Genetics, Center for Life Sciences and Technologies, Bogazici University, Istanbul, Turkey

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Yusuf T Abaci

7Department of Molecular Biology and Genetics, Center for Life Sciences and Technologies, Bogazici University, Istanbul, Turkey

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Gisele Mautino

1Ipsen Innovation, Les Ulis, France

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Florence Meyer-Losic

1Ipsen Innovation, Les Ulis, France

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Florence Jollivet

2Université de Paris, Hôpital St. Louis, Paris, France

3Institut National de la Santé et de la Recherche Médicale (INSERM) unité mixte de recherche (UMR) 944, Equipe labellisée par la Ligue Nationale contre le Cancer, Institut de Recherche St. Louis, Hôpital St. Louis, Paris, France

4 Centre National de la Recherche Scientifique (CNRS) UMR 7212, Hôpital St. Louis, Paris, France

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Tarig Bashir

1Ipsen Innovation, Les Ulis, France

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Hugues de Thé

2Université de Paris, Hôpital St. Louis, Paris, France

4 Centre National de la Recherche Scientifique (CNRS) UMR 7212, Hôpital St. Louis, Paris, France

5Assistance publique – Hôpitaux de Paris, Service de Biochimie, Hôpital St. Louis, Paris, France

6College de France, PSL Research University, INSERM UMR 1050, CNRS UMR 7241, Paris, France

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Umut Sahin

2Université de Paris, Hôpital St. Louis, Paris, France

4 Centre National de la Recherche Scientifique (CNRS) UMR 7212, Hôpital St. Louis, Paris, France

7Department of Molecular Biology and Genetics, Center for Life Sciences and Technologies, Bogazici University, Istanbul, Turkey

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ORCID record for Umut Sahin
For correspondence: umut.sahin@boun.edu.tr

Published 20 August 2019. DOI: 10.26508/lsa.201800213

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Drug-induced androgen receptor loss