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Research Article
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The S. Typhi effector StoD is an E3/E4 ubiquitin ligase which binds K48- and K63-linked diubiquitin

Melanie A McDowell, View ORCID ProfileAlexander MP Byrne, View ORCID ProfileElli Mylona, Rebecca Johnson, Agnes Sagfors, Valerie F Crepin, Susan Lea  Correspondence email, View ORCID ProfileGad Frankel  Correspondence email
Melanie A McDowell
1Sir William Dunn School of Pathology, University of Oxford, Oxford, UK
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Alexander MP Byrne
2MRC Centre for Molecular Bacteriology and Infection, Department of Life Sciences, Imperial College, London, UK
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  • ORCID record for Alexander MP Byrne
Elli Mylona
2MRC Centre for Molecular Bacteriology and Infection, Department of Life Sciences, Imperial College, London, UK
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  • ORCID record for Elli Mylona
Rebecca Johnson
2MRC Centre for Molecular Bacteriology and Infection, Department of Life Sciences, Imperial College, London, UK
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Agnes Sagfors
2MRC Centre for Molecular Bacteriology and Infection, Department of Life Sciences, Imperial College, London, UK
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Valerie F Crepin
2MRC Centre for Molecular Bacteriology and Infection, Department of Life Sciences, Imperial College, London, UK
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Susan Lea
1Sir William Dunn School of Pathology, University of Oxford, Oxford, UK
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  • For correspondence: susan.lea@path.ox.ac.uk
Gad Frankel
2MRC Centre for Molecular Bacteriology and Infection, Department of Life Sciences, Imperial College, London, UK
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  • ORCID record for Gad Frankel
  • For correspondence: g.frankel@imperial.ac.uk
Published 29 May 2019. DOI: 10.26508/lsa.201800272
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Article Information

vol. 2 no. 3 e201800272
DOI 
https://doi.org/10.26508/lsa.201800272
PubMed 
31142637

Published By 
Life Science Alliance
Online ISSN 
2575-1077
History 
  • Received December 10, 2018
  • Revision received May 3, 2019
  • Accepted May 7, 2019
  • Published online May 29, 2019.

Copyright & Usage 
© 2019 McDowell et al. This article is available under a Creative Commons License (Attribution 4.0 International, as described at https://creativecommons.org/licenses/by/4.0/).

Author Information

  1. Melanie A McDowell1,*,
  2. Alexander MP Byrne2,*,
  3. Elli Mylona2,
  4. Rebecca Johnson2,
  5. Agnes Sagfors2,
  6. Valerie F Crepin2,
  7. Susan Lea1⇑ and
  8. Gad Frankel2⇑
  1. 1Sir William Dunn School of Pathology, University of Oxford, Oxford, UK
  2. 2MRC Centre for Molecular Bacteriology and Infection, Department of Life Sciences, Imperial College, London, UK
  1. Correspondence: g.frankel{at}imperial.ac.uk
  2. susan.lea{at}path.ox.ac.uk
  1. ↵* Melanie A McDowell and Alexander MP Byrne contributed equally to this work

  • Melanie A McDowell’s present address is Biochemistry Centre (BZH), University of Heidelberg, Heidelberg, Germany

  • Alexander MP Byrne’s present address is Avian Virology and Mammalian Influenza Research, Virology Department, Animal and Plant Health Agency, Surrey, UK

View Full Text

Funding

  • Wellcome Trust Investigator Award

    100298/Z/12/Z
    S Lea
  • Wellcome Trust Investigator Award

    107057/Z/15/Z
    G Frankel
  • Biotechnology and Biological Sciences Research Council (BBSRC)

    BB/K001515/1
    G Frankel
  • BBSRC and Medical Research Council (MRC)

    AMP Byrne, R Johnson, E Mylona, A Sagfors
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The S. Typhi StoD binds diubiquitin
Melanie A McDowell, Alexander MP Byrne, Elli Mylona, Rebecca Johnson, Agnes Sagfors, Valerie F Crepin, Susan Lea, Gad Frankel
Life Science Alliance May 2019, 2 (3) e201800272; DOI: 10.26508/lsa.201800272

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The S. Typhi StoD binds diubiquitin
Melanie A McDowell, Alexander MP Byrne, Elli Mylona, Rebecca Johnson, Agnes Sagfors, Valerie F Crepin, Susan Lea, Gad Frankel
Life Science Alliance May 2019, 2 (3) e201800272; DOI: 10.26508/lsa.201800272
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Volume 2, No. 3
June 2019
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