A dual role for SAMHD1 in regulating HBV cccDNA and RT-dependent particle genesis

Peter AC Wing; Tamara Davenne; Jochen Wettengel; Alvina G Lai; Xiaodong Zhuang; Anindita Chakraborty; Valentina D’Arienzo; Catharina Kramer; Chunkyu Ko; James M Harris; Sabrina Schreiner; Martin Higgs; Stephanie Roessler; Joanna L Parish; Ulrike Protzer; Peter Balfe; Jan Rehwinkel; Jane A McKeating

doi:10.26508/lsa.201900355

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A dual role for SAMHD1 in regulating HBV cccDNA and RT-dependent particle genesis

View ORCID ProfilePeter AC Wing, Tamara Davenne, Jochen Wettengel, View ORCID ProfileAlvina G Lai, Xiaodong Zhuang, Anindita Chakraborty, Valentina D’Arienzo, Catharina Kramer, Chunkyu Ko, James M Harris, Sabrina Schreiner, View ORCID ProfileMartin Higgs, View ORCID ProfileStephanie Roessler, View ORCID ProfileJoanna L Parish, View ORCID ProfileUlrike Protzer, View ORCID ProfilePeter Balfe, View ORCID ProfileJan Rehwinkel, View ORCID ProfileJane A McKeating Correspondence email

Peter AC Wing

1Nuffield Department of Medicine, University of Oxford, Oxford, UK

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Tamara Davenne

2Medical Research Council Human Immunology Unit, Medical Research Council Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK

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Jochen Wettengel

3Institute of Virology, Technische Universität München/Helmholtz Zentrum München, Munich, Germany

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Alvina G Lai

1Nuffield Department of Medicine, University of Oxford, Oxford, UK

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Xiaodong Zhuang

1Nuffield Department of Medicine, University of Oxford, Oxford, UK

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Anindita Chakraborty

3Institute of Virology, Technische Universität München/Helmholtz Zentrum München, Munich, Germany

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Valentina D’Arienzo

1Nuffield Department of Medicine, University of Oxford, Oxford, UK

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Catharina Kramer

1Nuffield Department of Medicine, University of Oxford, Oxford, UK

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Chunkyu Ko

3Institute of Virology, Technische Universität München/Helmholtz Zentrum München, Munich, Germany

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James M Harris

1Nuffield Department of Medicine, University of Oxford, Oxford, UK

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Sabrina Schreiner

3Institute of Virology, Technische Universität München/Helmholtz Zentrum München, Munich, Germany

4German Center for Infection Research (DZIF), Munich Partner Site, Munich, Germany

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Martin Higgs

5Institutes of Cancer and Genomic Sciences and Immunity and Immunotherapy, College of Medical and Dental Sciences, University of Birmingham, UK

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Stephanie Roessler

6Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany

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Joanna L Parish

5Institutes of Cancer and Genomic Sciences and Immunity and Immunotherapy, College of Medical and Dental Sciences, University of Birmingham, UK

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Ulrike Protzer

3Institute of Virology, Technische Universität München/Helmholtz Zentrum München, Munich, Germany

4German Center for Infection Research (DZIF), Munich Partner Site, Munich, Germany

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Peter Balfe

5Institutes of Cancer and Genomic Sciences and Immunity and Immunotherapy, College of Medical and Dental Sciences, University of Birmingham, UK

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Jan Rehwinkel

2Medical Research Council Human Immunology Unit, Medical Research Council Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK

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Jane A McKeating

1Nuffield Department of Medicine, University of Oxford, Oxford, UK

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For correspondence: jane.mckeating@ndm.ox.ac.uk

Published 27 March 2019. DOI: 10.26508/lsa.201900355

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Dual role for SAMHD1 in HBV replication

Peter AC Wing, Tamara Davenne, Jochen Wettengel, Alvina G Lai, Xiaodong Zhuang, Anindita Chakraborty, Valentina D’Arienzo, Catharina Kramer, Chunkyu Ko, James M Harris, Sabrina Schreiner, Martin Higgs, Stephanie Roessler, Joanna L Parish, Ulrike Protzer, Peter Balfe, Jan Rehwinkel, Jane A McKeating

Life Science Alliance Mar 2019, 2 (2) e201900355; DOI: 10.26508/lsa.201900355

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Dual role for SAMHD1 in HBV replication

Life Science Alliance Mar 2019, 2 (2) e201900355; DOI: 10.26508/lsa.201900355

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