Research Article
Open Access
Drug screening with human SMN2 reporter identifies SMN protein stabilizers to correct SMA pathology
Yiran Wang, Chongchong Xu, Lin Ma, Yongchao Mou, Bowen Zhang, Shanshan Zhou, Yue Tian, Jessica Trinh, View ORCID ProfileXiaoqing Zhang Correspondence email, View ORCID ProfileXue-Jun Li Correspondence email
Yiran Wang
1Brain and Spinal Cord Innovative Research Center, Tongji Hospital, Tongji University School of Medicine, Shanghai, China
Chongchong Xu
2Department of Biomedical Sciences, University of Illinois College of Medicine Rockford, Rockford, IL, USA
3Department of Bioengineering, University of Illinois at Chicago, Chicago, IL, USA
Lin Ma
1Brain and Spinal Cord Innovative Research Center, Tongji Hospital, Tongji University School of Medicine, Shanghai, China
4Key Laboratory of Reconstruction and Regeneration of Spine and Spinal Cord Injury, Ministry of Education, Shanghai, China
5Key Laboratory of Neuroregeneration of Shanghai Universities, Tongji University, School of Medicine, Shanghai, China
Yongchao Mou
2Department of Biomedical Sciences, University of Illinois College of Medicine Rockford, Rockford, IL, USA
3Department of Bioengineering, University of Illinois at Chicago, Chicago, IL, USA
Bowen Zhang
1Brain and Spinal Cord Innovative Research Center, Tongji Hospital, Tongji University School of Medicine, Shanghai, China
Shanshan Zhou
1Brain and Spinal Cord Innovative Research Center, Tongji Hospital, Tongji University School of Medicine, Shanghai, China
Yue Tian
1Brain and Spinal Cord Innovative Research Center, Tongji Hospital, Tongji University School of Medicine, Shanghai, China
Jessica Trinh
2Department of Biomedical Sciences, University of Illinois College of Medicine Rockford, Rockford, IL, USA
Xiaoqing Zhang
1Brain and Spinal Cord Innovative Research Center, Tongji Hospital, Tongji University School of Medicine, Shanghai, China
4Key Laboratory of Reconstruction and Regeneration of Spine and Spinal Cord Injury, Ministry of Education, Shanghai, China
5Key Laboratory of Neuroregeneration of Shanghai Universities, Tongji University, School of Medicine, Shanghai, China
6Tsingtao Advanced Research Institute, Tongji University, Shanghai, China
7Shanghai Institute of Stem Cell Research and Clinical Translation, Shanghai, China
8Translational Medical Center for Stem Cell Therapy, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China
Xue-Jun Li
2Department of Biomedical Sciences, University of Illinois College of Medicine Rockford, Rockford, IL, USA
3Department of Bioengineering, University of Illinois at Chicago, Chicago, IL, USA
Published 25 March 2019. DOI: 10.26508/lsa.201800268
Inhibiting cysteine proteases for SMA
Yiran Wang, Chongchong Xu, Lin Ma, Yongchao Mou, Bowen Zhang, Shanshan Zhou, Yue Tian, Jessica Trinh, Xiaoqing Zhang, Xue-Jun Li
Life Science Alliance Mar 2019, 2 (2) e201800268; DOI: 10.26508/lsa.201800268
In this Issue
Volume 2, No. 2
April 2019
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