m6A-mRNA methylation regulates cardiac gene expression and cellular growth

Vivien Kmietczyk; Eva Riechert; Laura Kalinski; Etienne Boileau; Ellen Malovrh; Brandon Malone; Agnieszka Gorska; Christoph Hofmann; Eshita Varma; Lonny Jürgensen; Verena Kamuf-Schenk; Janine Altmüller; Rewati Tappu; Martin Busch; Patrick Most; Hugo A Katus; Christoph Dieterich; Mirko Völkers

doi:10.26508/lsa.201800233

Research Article

Open Access

m⁶A-mRNA methylation regulates cardiac gene expression and cellular growth

View ORCID ProfileVivien Kmietczyk, View ORCID ProfileEva Riechert, Laura Kalinski, View ORCID ProfileEtienne Boileau, View ORCID ProfileEllen Malovrh, Brandon Malone, Agnieszka Gorska, View ORCID ProfileChristoph Hofmann, Eshita Varma, Lonny Jürgensen, Verena Kamuf-Schenk, Janine Altmüller, Rewati Tappu, View ORCID ProfileMartin Busch, Patrick Most, Hugo A Katus, Christoph Dieterich, View ORCID ProfileMirko Völkers Correspondence email

Vivien Kmietczyk

Department of Cardiology, Angiology, and Pneumology, University Hospital Heidelberg, University of Heidelberg, Heidelberg, Germany

DZHK (German Centre for Cardiovascular Research), Partner Site Heidelberg/Mannheim, Heidelberg, Germany

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ORCID record for Vivien Kmietczyk

Eva Riechert

Department of Cardiology, Angiology, and Pneumology, University Hospital Heidelberg, University of Heidelberg, Heidelberg, Germany

DZHK (German Centre for Cardiovascular Research), Partner Site Heidelberg/Mannheim, Heidelberg, Germany

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ORCID record for Eva Riechert

Laura Kalinski

Department of Cardiology, Angiology, and Pneumology, University Hospital Heidelberg, University of Heidelberg, Heidelberg, Germany

DZHK (German Centre for Cardiovascular Research), Partner Site Heidelberg/Mannheim, Heidelberg, Germany

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Etienne Boileau

Department of Cardiology, Angiology, and Pneumology, University Hospital Heidelberg, University of Heidelberg, Heidelberg, Germany

DZHK (German Centre for Cardiovascular Research), Partner Site Heidelberg/Mannheim, Heidelberg, Germany

Section of Bioinformatics and Systems Cardiology, Department of Cardiology, Angiology, and Pneumology and Klaus Tschira Institute for Integrative Computational Cardiology, University of Heidelberg, Heidelberg, Germany

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Ellen Malovrh

Department of Cardiology, Angiology, and Pneumology, University Hospital Heidelberg, University of Heidelberg, Heidelberg, Germany

DZHK (German Centre for Cardiovascular Research), Partner Site Heidelberg/Mannheim, Heidelberg, Germany

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Brandon Malone

Department of Cardiology, Angiology, and Pneumology, University Hospital Heidelberg, University of Heidelberg, Heidelberg, Germany

DZHK (German Centre for Cardiovascular Research), Partner Site Heidelberg/Mannheim, Heidelberg, Germany

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Agnieszka Gorska

Department of Cardiology, Angiology, and Pneumology, University Hospital Heidelberg, University of Heidelberg, Heidelberg, Germany

DZHK (German Centre for Cardiovascular Research), Partner Site Heidelberg/Mannheim, Heidelberg, Germany

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Christoph Hofmann

Department of Cardiology, Angiology, and Pneumology, University Hospital Heidelberg, University of Heidelberg, Heidelberg, Germany

DZHK (German Centre for Cardiovascular Research), Partner Site Heidelberg/Mannheim, Heidelberg, Germany

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ORCID record for Christoph Hofmann

Eshita Varma

Department of Cardiology, Angiology, and Pneumology, University Hospital Heidelberg, University of Heidelberg, Heidelberg, Germany

DZHK (German Centre for Cardiovascular Research), Partner Site Heidelberg/Mannheim, Heidelberg, Germany

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Lonny Jürgensen

Department of Cardiology, Angiology, and Pneumology, University Hospital Heidelberg, University of Heidelberg, Heidelberg, Germany

DZHK (German Centre for Cardiovascular Research), Partner Site Heidelberg/Mannheim, Heidelberg, Germany

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Verena Kamuf-Schenk

Department of Cardiology, Angiology, and Pneumology, University Hospital Heidelberg, University of Heidelberg, Heidelberg, Germany

DZHK (German Centre for Cardiovascular Research), Partner Site Heidelberg/Mannheim, Heidelberg, Germany

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Janine Altmüller

Cologne Center for Genomics, University Cologne, Cologne, Germany

Center for Molecular Medicine Cologne, University of Cologne, Cologne, Germany

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Rewati Tappu

Department of Cardiology, Angiology, and Pneumology, University Hospital Heidelberg, University of Heidelberg, Heidelberg, Germany

DZHK (German Centre for Cardiovascular Research), Partner Site Heidelberg/Mannheim, Heidelberg, Germany

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Martin Busch

Department of Cardiology, Angiology, and Pneumology, University Hospital Heidelberg, University of Heidelberg, Heidelberg, Germany

DZHK (German Centre for Cardiovascular Research), Partner Site Heidelberg/Mannheim, Heidelberg, Germany

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ORCID record for Martin Busch

Patrick Most

Department of Cardiology, Angiology, and Pneumology, University Hospital Heidelberg, University of Heidelberg, Heidelberg, Germany

DZHK (German Centre for Cardiovascular Research), Partner Site Heidelberg/Mannheim, Heidelberg, Germany

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Hugo A Katus

Department of Cardiology, Angiology, and Pneumology, University Hospital Heidelberg, University of Heidelberg, Heidelberg, Germany

DZHK (German Centre for Cardiovascular Research), Partner Site Heidelberg/Mannheim, Heidelberg, Germany

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Christoph Dieterich

Department of Cardiology, Angiology, and Pneumology, University Hospital Heidelberg, University of Heidelberg, Heidelberg, Germany

DZHK (German Centre for Cardiovascular Research), Partner Site Heidelberg/Mannheim, Heidelberg, Germany

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Mirko Völkers

Department of Cardiology, Angiology, and Pneumology, University Hospital Heidelberg, University of Heidelberg, Heidelberg, Germany

DZHK (German Centre for Cardiovascular Research), Partner Site Heidelberg/Mannheim, Heidelberg, Germany

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ORCID record for Mirko Völkers
For correspondence: mirko.voelkers@med.uni-heidelberg.de

Published 9 April 2019. DOI: 10.26508/lsa.201800233

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Citation Tools

mRNA methylation in the myocardium

Vivien Kmietczyk, Eva Riechert, Laura Kalinski, Etienne Boileau, Ellen Malovrh, Brandon Malone, Agnieszka Gorska, Christoph Hofmann, Eshita Varma, Lonny Jürgensen, Verena Kamuf-Schenk, Janine Altmüller, Rewati Tappu, Martin Busch, Patrick Most, Hugo A Katus, Christoph Dieterich, Mirko Völkers

Life Science Alliance Apr 2019, 2 (2) e201800233; DOI: 10.26508/lsa.201800233