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Research Article
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MiR-146a wild-type 3′ sequence identity is dispensable for proper innate immune function in vivo

Grant Bertolet, Natee Kongchan, Rebekah Miller, Ravi K Patel, Antrix Jain, Jong Min Choi, Alexander B Saltzman, Amber Christenson, Sung Yun Jung, Anna Malovannaya, Andrew Grimson, View ORCID ProfileJoel R Neilson  Correspondence email
Grant Bertolet
1Graduate Program in Immunology, Baylor College of Medicine, Houston, TX, USA
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Natee Kongchan
2Department of Molecular Physiology and Biophysics, Baylor College of Medicine, Houston, TX, USA
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Rebekah Miller
6Department of Molecular Biology and Genetics, Cornell University, Ithaca, NY, USA
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Ravi K Patel
6Department of Molecular Biology and Genetics, Cornell University, Ithaca, NY, USA
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Antrix Jain
3Mass Spectrometry Proteomics Core, Baylor College of Medicine, Houston, TX, USA
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Jong Min Choi
3Mass Spectrometry Proteomics Core, Baylor College of Medicine, Houston, TX, USA
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Alexander B Saltzman
4Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX, USA
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Amber Christenson
2Department of Molecular Physiology and Biophysics, Baylor College of Medicine, Houston, TX, USA
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Sung Yun Jung
3Mass Spectrometry Proteomics Core, Baylor College of Medicine, Houston, TX, USA
4Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX, USA
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Anna Malovannaya
3Mass Spectrometry Proteomics Core, Baylor College of Medicine, Houston, TX, USA
4Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX, USA
5Dan L. Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX, USA
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Andrew Grimson
6Department of Molecular Biology and Genetics, Cornell University, Ithaca, NY, USA
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Joel R Neilson
1Graduate Program in Immunology, Baylor College of Medicine, Houston, TX, USA
2Department of Molecular Physiology and Biophysics, Baylor College of Medicine, Houston, TX, USA
5Dan L. Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX, USA
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  • ORCID record for Joel R Neilson
  • For correspondence: neilson@bcm.edu
Published 18 February 2019. DOI: 10.26508/lsa.201800249
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Article Information

vol. 2 no. 1 e201800249
DOI 
https://doi.org/10.26508/lsa.201800249
PubMed 
30777858

Published By 
Life Science Alliance
Online ISSN 
2575-1077
History 
  • Received November 19, 2018
  • Revision received January 31, 2019
  • Accepted February 1, 2019
  • Published online February 18, 2019.

Copyright & Usage 
© 2019 Bertolet et al. This article is available under a Creative Commons License (Attribution 4.0 International, as described at https://creativecommons.org/licenses/by/4.0/).

Author Information

  1. Grant Bertolet1,
  2. Natee Kongchan2,
  3. Rebekah Miller6,
  4. Ravi K Patel6,
  5. Antrix Jain3,
  6. Jong Min Choi3,
  7. Alexander B Saltzman4,
  8. Amber Christenson2,
  9. Sung Yun Jung3,4,
  10. Anna Malovannaya3,4,5,
  11. Andrew Grimson6 and
  12. Joel R Neilson1,2,5⇑
  1. 1Graduate Program in Immunology, Baylor College of Medicine, Houston, TX, USA
  2. 2Department of Molecular Physiology and Biophysics, Baylor College of Medicine, Houston, TX, USA
  3. 3Mass Spectrometry Proteomics Core, Baylor College of Medicine, Houston, TX, USA
  4. 4Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX, USA
  5. 5Dan L. Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX, USA
  6. 6Department of Molecular Biology and Genetics, Cornell University, Ithaca, NY, USA
  1. Correspondence: neilson{at}bcm.edu
View Full Text

Funding

  • Baylor College of Medicine

  • Nancy Chang Foundation

  • NIH

    CA190467
    JR Neilson
  • NIH

    T32AI053831; T32DK060445
    G Bertolet
  • Cell Sorting Core

    P30AI036211; P30CA125123; S10RR024574
  • RNA sequencing Core

    P50HD076210
  • MS Proteomics Core

    P30CA125123; CPRIT RP170005
  • Athena Water Breast Cancer Research Scholar of the American Cancer Society

    RSG-15-088-01RMC
    JR Neilson
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MiR-146a 3′ sequence identity is dispensable for function
Grant Bertolet, Natee Kongchan, Rebekah Miller, Ravi K Patel, Antrix Jain, Jong Min Choi, Alexander B Saltzman, Amber Christenson, Sung Yun Jung, Anna Malovannaya, Andrew Grimson, Joel R Neilson
Life Science Alliance Feb 2019, 2 (1) e201800249; DOI: 10.26508/lsa.201800249

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MiR-146a 3′ sequence identity is dispensable for function
Grant Bertolet, Natee Kongchan, Rebekah Miller, Ravi K Patel, Antrix Jain, Jong Min Choi, Alexander B Saltzman, Amber Christenson, Sung Yun Jung, Anna Malovannaya, Andrew Grimson, Joel R Neilson
Life Science Alliance Feb 2019, 2 (1) e201800249; DOI: 10.26508/lsa.201800249
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Volume 2, No. 1
February 2019
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