Mucosa-associated microbiota drives pathogenic functions in IBD-derived intestinal iNKT cells

Claudia Burrello; Gabriella Pellegrino; Maria Rita Giuffrè; Giulia Lovati; Ilaria Magagna; Alice Bertocchi; Fulvia Milena Cribiù; Francesca Boggio; Fiorenzo Botti; Elena Trombetta; Laura Porretti; Antonio Di Sabatino; Maurizio Vecchi; Maria Rescigno; Flavio Caprioli; Federica Facciotti

doi:10.26508/lsa.201800229

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Mucosa-associated microbiota drives pathogenic functions in IBD-derived intestinal iNKT cells

View ORCID ProfileClaudia Burrello, Gabriella Pellegrino, Maria Rita Giuffrè, Giulia Lovati, Ilaria Magagna, Alice Bertocchi, Fulvia Milena Cribiù, Francesca Boggio, Fiorenzo Botti, Elena Trombetta, View ORCID ProfileLaura Porretti, Antonio Di Sabatino, Maurizio Vecchi, Maria Rescigno, Flavio Caprioli, View ORCID ProfileFederica Facciotti Correspondence email

Claudia Burrello

1Department of Experimental Oncology, IEO, European Istitute of Oncology IRCCS, Milan, Italy

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Gabriella Pellegrino

2Gastroenterology and Endoscopy Unit, Fondazione IRCCS Ca’ Granda, Ospedale Maggiore Policlinico, Milan, Italy

3Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Milan, Italy

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Maria Rita Giuffrè

2Gastroenterology and Endoscopy Unit, Fondazione IRCCS Ca’ Granda, Ospedale Maggiore Policlinico, Milan, Italy

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Giulia Lovati

1Department of Experimental Oncology, IEO, European Istitute of Oncology IRCCS, Milan, Italy

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Ilaria Magagna

1Department of Experimental Oncology, IEO, European Istitute of Oncology IRCCS, Milan, Italy

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Alice Bertocchi

1Department of Experimental Oncology, IEO, European Istitute of Oncology IRCCS, Milan, Italy

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Fulvia Milena Cribiù

4Pathology Unit, Fondazione IRCCS Ca’ Granda, Ospedale Maggiore Policlinico, Milan, Italy

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Francesca Boggio

4Pathology Unit, Fondazione IRCCS Ca’ Granda, Ospedale Maggiore Policlinico, Milan, Italy

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Fiorenzo Botti

3Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Milan, Italy

5General and Emergency Surgery Unit, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milan, Italy

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Elena Trombetta

6Flow Cytometry Service, Clinical Chemistry and Microbiology Laboratory Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milan, Italy

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Laura Porretti

6Flow Cytometry Service, Clinical Chemistry and Microbiology Laboratory Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milan, Italy

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ORCID record for Laura Porretti

Antonio Di Sabatino

7First Department of Internal Medicine, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy

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Maurizio Vecchi

2Gastroenterology and Endoscopy Unit, Fondazione IRCCS Ca’ Granda, Ospedale Maggiore Policlinico, Milan, Italy

3Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Milan, Italy

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Maria Rescigno

1Department of Experimental Oncology, IEO, European Istitute of Oncology IRCCS, Milan, Italy

8Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Italy

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Flavio Caprioli

2Gastroenterology and Endoscopy Unit, Fondazione IRCCS Ca’ Granda, Ospedale Maggiore Policlinico, Milan, Italy

3Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Milan, Italy

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Federica Facciotti

1Department of Experimental Oncology, IEO, European Istitute of Oncology IRCCS, Milan, Italy

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ORCID record for Federica Facciotti
For correspondence: Federica.facciotti@ieo.it

Published 13 February 2019. DOI: 10.26508/lsa.201800229

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Pro-inflammatory role of iNKT cells in IBD

Claudia Burrello, Gabriella Pellegrino, Maria Rita Giuffrè, Giulia Lovati, Ilaria Magagna, Alice Bertocchi, Fulvia Milena Cribiù, Francesca Boggio, Fiorenzo Botti, Elena Trombetta, Laura Porretti, Antonio Di Sabatino, Maurizio Vecchi, Maria Rescigno, Flavio Caprioli, Federica Facciotti

Life Science Alliance Feb 2019, 2 (1) e201800229; DOI: 10.26508/lsa.201800229

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Pro-inflammatory role of iNKT cells in IBD

Life Science Alliance Feb 2019, 2 (1) e201800229; DOI: 10.26508/lsa.201800229

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