Vamorolone targets dual nuclear receptors to treat inflammation and dystrophic cardiomyopathy

Christopher R Heier; Qing Yu; Alyson A Fiorillo; Christopher B Tully; Asya Tucker; Davi A Mazala; Kitipong Uaesoontrachoon; Sadish Srinivassane; Jesse M Damsker; Eric P Hoffman; Kanneboyina Nagaraju; Christopher F Spurney

doi:10.26508/lsa.201800186

Research Article

Open Access

Vamorolone targets dual nuclear receptors to treat inflammation and dystrophic cardiomyopathy

View ORCID ProfileChristopher R Heier Correspondence email, Qing Yu, Alyson A Fiorillo, Christopher B Tully, Asya Tucker, Davi A Mazala, Kitipong Uaesoontrachoon, Sadish Srinivassane, Jesse M Damsker, Eric P Hoffman, Kanneboyina Nagaraju, Christopher F Spurney

Christopher R Heier

1Department of Genomics and Precision Medicine, George Washington University School of Medicine and Health Sciences, Washington, DC, USA

2Center for Genetic Medicine Research, Children's National Medical Center, Washington, DC, USA

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
ORCID record for Christopher R Heier
For correspondence: cheier@childrensnational.org

Qing Yu

2Center for Genetic Medicine Research, Children's National Medical Center, Washington, DC, USA

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Alyson A Fiorillo

1Department of Genomics and Precision Medicine, George Washington University School of Medicine and Health Sciences, Washington, DC, USA

2Center for Genetic Medicine Research, Children's National Medical Center, Washington, DC, USA

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Christopher B Tully

2Center for Genetic Medicine Research, Children's National Medical Center, Washington, DC, USA

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Asya Tucker

2Center for Genetic Medicine Research, Children's National Medical Center, Washington, DC, USA

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Davi A Mazala

2Center for Genetic Medicine Research, Children's National Medical Center, Washington, DC, USA

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Kitipong Uaesoontrachoon

3AGADA Biosciences Incorporated, Halifax, Nova Scotia, Canada

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Sadish Srinivassane

3AGADA Biosciences Incorporated, Halifax, Nova Scotia, Canada

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Jesse M Damsker

4ReveraGen BioPharma, Incorporated, Rockville, MD, USA

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Eric P Hoffman

3AGADA Biosciences Incorporated, Halifax, Nova Scotia, Canada

4ReveraGen BioPharma, Incorporated, Rockville, MD, USA

5School of Pharmacy and Pharmaceutical Sciences, Binghamton University—State University of New York (SUNY), Binghamton, NY, USA

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Kanneboyina Nagaraju

3AGADA Biosciences Incorporated, Halifax, Nova Scotia, Canada

4ReveraGen BioPharma, Incorporated, Rockville, MD, USA

5School of Pharmacy and Pharmaceutical Sciences, Binghamton University—State University of New York (SUNY), Binghamton, NY, USA

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Christopher F Spurney

1Department of Genomics and Precision Medicine, George Washington University School of Medicine and Health Sciences, Washington, DC, USA

2Center for Genetic Medicine Research, Children's National Medical Center, Washington, DC, USA

6Division of Cardiology, Children's National Heart Institute, Children's National Medical Center, Washington, DC, USA

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Published 11 February 2019. DOI: 10.26508/lsa.201800186

Article
Figures & Data
Info
Metrics
Reviewer Comments
PDF

You are using an old browser, click here to download PDF

PDF Container

PreviousNext

Download PDF

Article Alerts

User Name *

Password *

Email *

Email Article

Thank you for your interest in spreading the word on Life Science Alliance.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Your Email *

Your Name *

Send To *

Enter multiple addresses on separate lines or separate them with commas.

You are going to email the following Vamorolone targets dual nuclear receptors to treat inflammation and dystrophic cardiomyopathy

Message Subject (Your Name) has sent you a message from Life Science Alliance

Message Body (Your Name) thought you would like to see the Life Science Alliance web site.

Your Personal Message

CAPTCHA

This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.

Citation Tools

Effects of nuclear receptor ligands in DMD

Christopher R Heier, Qing Yu, Alyson A Fiorillo, Christopher B Tully, Asya Tucker, Davi A Mazala, Kitipong Uaesoontrachoon, Sadish Srinivassane, Jesse M Damsker, Eric P Hoffman, Kanneboyina Nagaraju, Christopher F Spurney

Life Science Alliance Feb 2019, 2 (1) e201800186; DOI: 10.26508/lsa.201800186

Citation Manager Formats

BibTeX
Bookends
EasyBib
EndNote (tagged)
EndNote 8 (xml)
Medlars
Mendeley
Papers
RefWorks Tagged
Ref Manager
RIS
Zotero

Effects of nuclear receptor ligands in DMD

Life Science Alliance Feb 2019, 2 (1) e201800186; DOI: 10.26508/lsa.201800186

Share This Article:

Tweet Widget
Facebook Like

In this Issue

Volume 2, No. 1

February 2019

Table of Contents
Cover (PDF)
About the Cover
Masthead (PDF)

Jump to section

Article
Figures & Data
Info
Metrics
Reviewer Comments
PDF

Subjects

Pharmacology & Biotechnology
Molecular Biology
Genetics, Gene Therapy & Genetic Disease

No related articles found.

Cited By...

Current state of cardiac troponin testing in Duchenne muscular dystrophy cardiomyopathy: review and recommendations from the Parent Project Muscular Dystrophy expert panel
Disruption of a key ligand-H-bond network drives dissociative properties in vamorolone for Duchenne muscular dystrophy treatment

Google Scholar

Main menu

User menu

Search

Vamorolone targets dual nuclear receptors to treat inflammation and dystrophic cardiomyopathy

Citation Manager Formats

In this Issue

Subjects

Related Articles

Cited By...

More in this TOC Section

Similar Articles

Content

For Authors

Other Services

More Information