Vamorolone targets dual nuclear receptors to treat inflammation and dystrophic cardiomyopathy

Christopher R Heier; Qing Yu; Alyson A Fiorillo; Christopher B Tully; Asya Tucker; Davi A Mazala; Kitipong Uaesoontrachoon; Sadish Srinivassane; Jesse M Damsker; Eric P Hoffman; Kanneboyina Nagaraju; Christopher F Spurney

doi:10.26508/lsa.201800186

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Vamorolone targets dual nuclear receptors to treat inflammation and dystrophic cardiomyopathy

View ORCID ProfileChristopher R Heier Correspondence email, Qing Yu, Alyson A Fiorillo, Christopher B Tully, Asya Tucker, Davi A Mazala, Kitipong Uaesoontrachoon, Sadish Srinivassane, Jesse M Damsker, Eric P Hoffman, Kanneboyina Nagaraju, Christopher F Spurney

Christopher R Heier

1Department of Genomics and Precision Medicine, George Washington University School of Medicine and Health Sciences, Washington, DC, USA

2Center for Genetic Medicine Research, Children's National Medical Center, Washington, DC, USA

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ORCID record for Christopher R Heier
For correspondence: cheier@childrensnational.org

Qing Yu

2Center for Genetic Medicine Research, Children's National Medical Center, Washington, DC, USA

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Alyson A Fiorillo

1Department of Genomics and Precision Medicine, George Washington University School of Medicine and Health Sciences, Washington, DC, USA

2Center for Genetic Medicine Research, Children's National Medical Center, Washington, DC, USA

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Christopher B Tully

2Center for Genetic Medicine Research, Children's National Medical Center, Washington, DC, USA

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Asya Tucker

2Center for Genetic Medicine Research, Children's National Medical Center, Washington, DC, USA

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Davi A Mazala

2Center for Genetic Medicine Research, Children's National Medical Center, Washington, DC, USA

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Kitipong Uaesoontrachoon

3AGADA Biosciences Incorporated, Halifax, Nova Scotia, Canada

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Sadish Srinivassane

3AGADA Biosciences Incorporated, Halifax, Nova Scotia, Canada

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Jesse M Damsker

4ReveraGen BioPharma, Incorporated, Rockville, MD, USA

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Eric P Hoffman

3AGADA Biosciences Incorporated, Halifax, Nova Scotia, Canada

4ReveraGen BioPharma, Incorporated, Rockville, MD, USA

5School of Pharmacy and Pharmaceutical Sciences, Binghamton University—State University of New York (SUNY), Binghamton, NY, USA

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Kanneboyina Nagaraju

3AGADA Biosciences Incorporated, Halifax, Nova Scotia, Canada

4ReveraGen BioPharma, Incorporated, Rockville, MD, USA

5School of Pharmacy and Pharmaceutical Sciences, Binghamton University—State University of New York (SUNY), Binghamton, NY, USA

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Christopher F Spurney

1Department of Genomics and Precision Medicine, George Washington University School of Medicine and Health Sciences, Washington, DC, USA

2Center for Genetic Medicine Research, Children's National Medical Center, Washington, DC, USA

6Division of Cardiology, Children's National Heart Institute, Children's National Medical Center, Washington, DC, USA

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Published 11 February 2019. DOI: 10.26508/lsa.201800186

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Effects of nuclear receptor ligands in DMD

Christopher R Heier, Qing Yu, Alyson A Fiorillo, Christopher B Tully, Asya Tucker, Davi A Mazala, Kitipong Uaesoontrachoon, Sadish Srinivassane, Jesse M Damsker, Eric P Hoffman, Kanneboyina Nagaraju, Christopher F Spurney

Life Science Alliance Feb 2019, 2 (1) e201800186; DOI: 10.26508/lsa.201800186