Research Article
Open Access
Folding–function relationship of the most common cystic fibrosis–causing CFTR conductance mutants
Marcel van Willigen, Annelotte M Vonk, Hui Ying Yeoh, Evelien Kruisselbrink, Bertrand Kleizen, Cornelis K van der Ent, Maarten R Egmond, Hugo R de Jonge, View ORCID ProfileIneke Braakman, Jeffrey M Beekman, View ORCID ProfilePeter van der Sluijs Correspondence email
Marcel van Willigen
1Cellular Protein Chemistry, Department of Chemistry, Utrecht University, Utrecht, The Netherlands
Annelotte M Vonk
2Department of Pediatric Pulmonology, Wilhelmina Children's Hospital, University Medical Center, Utrecht, The Netherlands
Hui Ying Yeoh
1Cellular Protein Chemistry, Department of Chemistry, Utrecht University, Utrecht, The Netherlands
Evelien Kruisselbrink
2Department of Pediatric Pulmonology, Wilhelmina Children's Hospital, University Medical Center, Utrecht, The Netherlands
Bertrand Kleizen
1Cellular Protein Chemistry, Department of Chemistry, Utrecht University, Utrecht, The Netherlands
Cornelis K van der Ent
2Department of Pediatric Pulmonology, Wilhelmina Children's Hospital, University Medical Center, Utrecht, The Netherlands
Maarten R Egmond
1Cellular Protein Chemistry, Department of Chemistry, Utrecht University, Utrecht, The Netherlands
3Membrane Biochemistry and Biophysics, Department of Chemistry, Utrecht University, Utrecht, The Netherlands
Hugo R de Jonge
4Department of Gastroenterology and Hepatology, Erasmus University Medical Center, Rotterdam, The Netherlands
Ineke Braakman
1Cellular Protein Chemistry, Department of Chemistry, Utrecht University, Utrecht, The Netherlands
Jeffrey M Beekman
2Department of Pediatric Pulmonology, Wilhelmina Children's Hospital, University Medical Center, Utrecht, The Netherlands
Peter van der Sluijs
1Cellular Protein Chemistry, Department of Chemistry, Utrecht University, Utrecht, The Netherlands
Published 18 January 2019. DOI: 10.26508/lsa.201800172
Folding–function relationship of CF mutants
Marcel van Willigen, Annelotte M Vonk, Hui Ying Yeoh, Evelien Kruisselbrink, Bertrand Kleizen, Cornelis K van der Ent, Maarten R Egmond, Hugo R de Jonge, Ineke Braakman, Jeffrey M Beekman, Peter van der Sluijs
Life Science Alliance Jan 2019, 2 (1) e201800172; DOI: 10.26508/lsa.201800172
Folding–function relationship of CF mutants
Marcel van Willigen, Annelotte M Vonk, Hui Ying Yeoh, Evelien Kruisselbrink, Bertrand Kleizen, Cornelis K van der Ent, Maarten R Egmond, Hugo R de Jonge, Ineke Braakman, Jeffrey M Beekman, Peter van der Sluijs
Life Science Alliance Jan 2019, 2 (1) e201800172; DOI: 10.26508/lsa.201800172
In this Issue
Volume 2, No. 1
February 2019
Advertisement
Jump to section
Related Articles
- No related articles found.
Cited By...
- Rectal organoid-guided CFTR modulator therapy restores lung function in a cystic fibrosis patient with the rare 1677delTA/R334W genotype
- ABC-transporter CFTR folds with high fidelity through a modular, stepwise pathway
- Co-translational folding of the first transmembrane domain of ABC-transporter CFTR is supported by assembly with the first cytosolic domain
- Fluorescence assay for simultaneous quantification of CFTR ion-channel function and plasma membrane proximity
- Fluorescence assay for simultaneous quantification of CFTR ion-channel function and plasma membrane proximity