Table of Contents

Research Articles

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  Open Access

  Substrate fluxes in brown adipocytes upon adrenergic stimulation and uncoupling protein 1 ablation

  Sabine Schweizer, Josef Oeckl, Martin Klingenspor, Tobias Fromme

  Sabine Schweizer ... Tobias Fromme

  Published 14 November 2018
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  Open Access

  Plk1 regulates spindle orientation by phosphorylating NuMA in human cells

  Shrividya Sana, Riya Keshri, Ashwathi Rajeevan, Sukriti Kapoor, Sachin Kotak

  Shrividya Sana ... Sachin Kotak

  Published 16 November 2018
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  Open Access

  The BMP2/4 ortholog Dpp can function as an inter-organ signal that regulates developmental timing

  Linda Setiawan, Xueyang Pan, Alexis L Woods, Michael B O'Connor, Iswar K Hariharan

  Linda Setiawan ... Iswar K Hariharan

  Published 19 November 2018
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  Open Access

  Extracellular vesicles from mature dendritic cells (DC) differentiate monocytes into immature DC

  Stefan Schierer, Christian Ostalecki, Elisabeth Zinser, Ricarda Lamprecht, Bianca Plosnita, Lena Stich, Jan Dörrie, Manfred B Lutz, Gerold Schuler, Andreas S Baur

  Stefan Schierer ... Andreas S Baur

  Published 3 December 2018
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  Open Access

  Peroxisome biogenesis deficiency attenuates the BDNF-TrkB pathway-mediated development of the cerebellum

  Yuichi Abe, Masanori Honsho, Ryota Itoh, Ryoko Kawaguchi, Masashi Fujitani, Kazushirou Fujiwara, Masaaki Hirokane, Takashi Matsuzaki, Keiko Nakayama, Ryohei Ohgi, Toshihiro Marutani, Keiichi I Nakayama, Toshihide Yamashita, Yukio Fujiki

  Yuichi Abe ... Yukio Fujiki

  Published 3 December 2018
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  Open Access

  Dimerization and auto-processing induce caspase-11 protease activation within the non-canonical inflammasome

  Connie Ross, Amy H Chan, Jessica Von Pein, Dave Boucher, Kate Schroder

  Connie Ross ... Kate Schroder

  Published 6 December 2018
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  Open Access

  Mouse REC114 is essential for meiotic DNA double-strand break formation and forms a complex with MEI4

  Rajeev Kumar, Cecilia Oliver, Christine Brun, Ariadna B Juarez-Martinez, Yara Tarabay, Jan Kadlec, Bernard de Massy

  Rajeev Kumar ... Bernard de Massy

  Published 10 December 2018
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  Open Access

  A role for MED14 and UVH6 in heterochromatin transcription upon destabilization of silencing

  Pierre Bourguet, Stève de Bossoreille, Leticia López-González, Marie-Noëlle Pouch-Pélissier, Ángeles Gómez-Zambrano, Anthony Devert, Thierry Pélissier, Romain Pogorelcnik, Isabelle Vaillant, Olivier Mathieu

  Pierre Bourguet ... Olivier Mathieu

  Published 12 December 2018
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  Open Access

  Variants of DNMT3A cause transcript-specific DNA methylation patterns and affect hematopoiesis

  Tanja Božić, Joana Frobel, Annamarija Raic, Fabio Ticconi, Chao-Chung Kuo, Stefanie Heilmann-Heimbach, Tamme W Goecke, Martin Zenke, Edgar Jost, Ivan G Costa, Wolfgang Wagner

  Tanja Božić ... Wolfgang Wagner

  Published 13 December 2018
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  Open Access

  Absence of MHC-II expression by lymph node stromal cells results in autoimmunity

  Juan Dubrot, Fernanda V Duraes, Guillaume Harlé, Anjalie Schlaeppi, Dale Brighouse, Natacha Madelon, Christine Göpfert, Nadine Stokar-Regenscheit, Hans Acha-Orbea, Walter Reith, Monique Gannagé, Stephanie Hugues

  Juan Dubrot ... Stephanie Hugues

  Published 17 December 2018
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  Open Access

  Chemical genetic identification of GAK substrates reveals its role in regulating Na⁺/K⁺-ATPase

  Amy W Lin, Kalbinder K Gill, Marisol Sampedro Castañeda, Irene Matucci, Noreen Eder, Suzanne Claxton, Helen Flynn, Ambrosius P Snijders, Roger George, Sila K Ultanir

  Amy W Lin ... Sila K Ultanir

  Published 31 December 2018
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  Open Access

  Direct binding of Cdt2 to PCNA is important for targeting the CRL4^Cdt2 E3 ligase activity to Cdt1

  Akiyo Hayashi, Nickolaos Nikiforos Giakoumakis, Tatjana Heidebrecht, Takashi Ishii, Andreas Panagopoulos, Christophe Caillat, Michiyo Takahara, Richard G Hibbert, Naohiro Suenaga, Magda Stadnik-Spiewak, Tatsuro Takahashi, Yasushi Shiomi, Stavros Taraviras, Eleonore von Castelmur, Zoi Lygerou, Anastassis Perrakis, Hideo Nishitani

  Akiyo Hayashi ... Hideo Nishitani

  Published 31 December 2018