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JIP2 haploinsufficiency contributes to neurodevelopmental abnormalities in human pluripotent stem cell–derived neural progenitors and cortical neurons

View ORCID ProfileReinhard Roessler, Johanna Goldmann, Chikdu Shivalila, View ORCID ProfileRudolf Jaenisch  Correspondence email
Reinhard Roessler
1Whitehead Institute for Biomedical Research, Cambridge, MA, USA
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  • ORCID record for Reinhard Roessler
Johanna Goldmann
1Whitehead Institute for Biomedical Research, Cambridge, MA, USA
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Chikdu Shivalila
1Whitehead Institute for Biomedical Research, Cambridge, MA, USA
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Rudolf Jaenisch
1Whitehead Institute for Biomedical Research, Cambridge, MA, USA
2Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA
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  • ORCID record for Rudolf Jaenisch
  • For correspondence: jaenisch@wi.mit.edu
Published 25 June 2018. DOI: 10.26508/lsa.201800094
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Article Information

vol. 1 no. 4 e201800094
DOI 
https://doi.org/10.26508/lsa.201800094
PubMed 
30456368

Published By 
Life Science Alliance
Online ISSN 
2575-1077
History 
  • Received May 23, 2018
  • Revision received June 6, 2018
  • Accepted June 7, 2018
  • Published online June 25, 2018.

Copyright & Usage 
© 2018 Roessler et al. This article is available under a Creative Commons License (Attribution 4.0 International, as described at https://creativecommons.org/licenses/by/4.0/).

Author Information

  1. Reinhard Roessler1,
  2. Johanna Goldmann1,
  3. Chikdu Shivalila1 and
  4. Rudolf Jaenisch1,2⇑
  1. 1Whitehead Institute for Biomedical Research, Cambridge, MA, USA
  2. 2Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA
  1. Correspondence: jaenisch{at}wi.mit.edu
View Full Text

Funding

  • Simons Foundation

  • NIH

    1R01NS088538-01; HD 045022; 2R01MH104610-15
    R Jaenisch
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Role of JIP2 in 22qDS iPSC neuron differentiation
Reinhard Roessler, Johanna Goldmann, Chikdu Shivalila, Rudolf Jaenisch
Life Science Alliance Jun 2018, 1 (4) e201800094; DOI: 10.26508/lsa.201800094

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Role of JIP2 in 22qDS iPSC neuron differentiation
Reinhard Roessler, Johanna Goldmann, Chikdu Shivalila, Rudolf Jaenisch
Life Science Alliance Jun 2018, 1 (4) e201800094; DOI: 10.26508/lsa.201800094
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Volume 1, No. 4
August 2018
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  • Stem Cells
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