The expansion in lymphoid organs of IL-4+ BATF+ T follicular helper cells is linked to IgG4 class switching in vivo

Takashi Maehara; Hamid Mattoo; Vinay S Mahajan; Samuel JH Murphy; Grace J Yuen; Noriko Ishiguro; Miho Ohta; Masafumi Moriyama; Takako Saeki; Hidetaka Yamamoto; Masaki Yamauchi; Joe Daccache; Tamotsu Kiyoshima; Seiji Nakamura; John H Stone; Shiv Pillai

doi:10.26508/lsa.201800050

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The expansion in lymphoid organs of IL-4⁺ BATF⁺ T follicular helper cells is linked to IgG4 class switching in vivo

Takashi Maehara, Hamid Mattoo, View ORCID ProfileVinay S Mahajan, View ORCID ProfileSamuel JH Murphy, Grace J Yuen, Noriko Ishiguro, Miho Ohta, Masafumi Moriyama, View ORCID ProfileTakako Saeki, Hidetaka Yamamoto, Masaki Yamauchi, Joe Daccache, Tamotsu Kiyoshima, Seiji Nakamura, John H Stone, View ORCID ProfileShiv Pillai Correspondence email

Takashi Maehara

1Ragon Institute of MGH, MIT, and Harvard, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA

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Hamid Mattoo

1Ragon Institute of MGH, MIT, and Harvard, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA

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Vinay S Mahajan

1Ragon Institute of MGH, MIT, and Harvard, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA

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ORCID record for Vinay S Mahajan

Samuel JH Murphy

1Ragon Institute of MGH, MIT, and Harvard, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA

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Grace J Yuen

1Ragon Institute of MGH, MIT, and Harvard, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA

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Noriko Ishiguro

2Section of Oral and Maxillofacial Oncology, Division of Maxillofacial Diagnostic and Surgical Sciences, Faculty of Dental Science, Kyushu University, Fukuoka, Japan

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Miho Ohta

2Section of Oral and Maxillofacial Oncology, Division of Maxillofacial Diagnostic and Surgical Sciences, Faculty of Dental Science, Kyushu University, Fukuoka, Japan

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Masafumi Moriyama

2Section of Oral and Maxillofacial Oncology, Division of Maxillofacial Diagnostic and Surgical Sciences, Faculty of Dental Science, Kyushu University, Fukuoka, Japan

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Takako Saeki

3Department of Internal Medicine, Nagaoka Red Cross Hospital, Nagaoka, Japan

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ORCID record for Takako Saeki

Hidetaka Yamamoto

4Division of Diagnostic Pathology, Kyushu University Hospital, Fukuoka, Japan

5Department of Anatomic Pathology, Kyushu University, Fukuoka, Japan

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Masaki Yamauchi

2Section of Oral and Maxillofacial Oncology, Division of Maxillofacial Diagnostic and Surgical Sciences, Faculty of Dental Science, Kyushu University, Fukuoka, Japan

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Joe Daccache

1Ragon Institute of MGH, MIT, and Harvard, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA

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Tamotsu Kiyoshima

6Laboratory of Oral Pathology, Division of Maxillofacial Diagnostic and Surgical Sciences, Faculty of Dental Science, Kyushu University, Fukuoka, Japan

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Seiji Nakamura

2Section of Oral and Maxillofacial Oncology, Division of Maxillofacial Diagnostic and Surgical Sciences, Faculty of Dental Science, Kyushu University, Fukuoka, Japan

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John H Stone

7Division of Rheumatology, Allergy, and Immunology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA

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Shiv Pillai

1Ragon Institute of MGH, MIT, and Harvard, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA

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ORCID record for Shiv Pillai
For correspondence: pillai@helix.mgh.harvard.edu

Published 5 April 2018. DOI: 10.26508/lsa.201800050

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IL-4–secreting T_FH cells

Takashi Maehara, Hamid Mattoo, Vinay S Mahajan, Samuel JH Murphy, Grace J Yuen, Noriko Ishiguro, Miho Ohta, Masafumi Moriyama, Takako Saeki, Hidetaka Yamamoto, Masaki Yamauchi, Joe Daccache, Tamotsu Kiyoshima, Seiji Nakamura, John H Stone, Shiv Pillai

Life Science Alliance Apr 2018, 1 (1) e201800050; DOI: 10.26508/lsa.201800050

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IL-4–secreting T_FH cells

Life Science Alliance Apr 2018, 1 (1) e201800050; DOI: 10.26508/lsa.201800050

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