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The spread of SARS-CoV-2 continues to quickly evolve in many countries, and many research institutions have been subject to temporary shutdowns.
Life Science Alliance remains fully functional and will continue to publish as before and is open to submissions, as well as presubmission or any other inquiries, such as reaching out to us with reviewer reports obtained at another journal.
Our staff is working remotely and is reachable via email and phone
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  • Regulation of SC formation by SCF
  • Re-epithelialization of scratch wounds
  • Brown preadipocyte heterogeneity
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Newest Articles

  • Open Access
    Correction: MALDI-IMS combined with shotgun proteomics identify and localize new factors in male infertility

    Shibojyoti Lahiri, Wasim Aftab, Lena Walenta, Leena Strauss, Matti Poutanen, Artur Mayerhofer, Axel Imhof

    Shibojyoti Lahiri ... Axel Imhof

    Published 21 January 2021

    Correction

  • ER targeting of non-imported mitochondrial carrier proteins is dependent on the GET pathway
    Open Access
    ER targeting of non-imported mitochondrial carrier proteins is dependent on the GET pathway

    Tianyao Xiao, Viplendra PS Shakya, Adam L Hughes

    Tianyao Xiao ... Adam L Hughes

    Published 21 January 2021

    The GET pathway is required to target non-imported mitochondrial carrier proteins to the endoplasmic reticulum, which prevents their deposition into Hsp42-dependent protein foci.

  • Reduced RNA turnover as a driver of cellular senescence
    Open Access
    Reduced RNA turnover as a driver of cellular senescence

    Nowsheen Mullani, Yevheniia Porozhan, Adèle Mangelinck, Christophe Rachez, Mickael Costallat, Eric Batsché, Michele Goodhardt, Giovanni Cenci, Carl Mann, Christian Muchardt

    Nowsheen Mullani ... Christian Muchardt

    Published 14 January 2021

    RNAs originating from transcription upstream and downstream of genes accumulate in the cytoplasm of a subset of senescent cells, suggesting an RNA alternative to cytoplasmic DNA in the triggering of senescence.

  • MALDI-IMS combined with shotgun proteomics identify and localize new factors in male infertility
    Open Access
    MALDI-IMS combined with shotgun proteomics identify and localize new factors in male infertility

    Shibojyoti Lahiri, Wasim Aftab, Lena Walenta, Leena Strauss, Matti Poutanen, Artur Mayerhofer, Axel Imhof

    Shibojyoti Lahiri ... Axel Imhof

    Published 6 January 2021

    In situ proteomics of male infertility.

  • Cyclin A2 localises in the cytoplasm at the S/G2 transition to activate PLK1
    Open Access
    Cyclin A2 localises in the cytoplasm at the S/G2 transition to activate PLK1

    Helena Silva Cascales, Kamila Burdova, Anna Middleton, Vladislav Kuzin, Erik Müllers, Henriette Stoy, Laura Baranello, Libor Macurek, Arne Lindqvist

    Helena Silva Cascales ... Arne Lindqvist

    Published 5 January 2021

    Main mitotic kinases as PLK1 are activated at the S/G2 transition. A change in Cyclin A2 localisation at the S/G2 transition enables activation of PLK1.

  • Different mutant RUNX1 oncoproteins program alternate haematopoietic differentiation trajectories
    Open Access
    Different mutant RUNX1 oncoproteins program alternate haematopoietic differentiation trajectories

    Sophie G Kellaway, Peter Keane, Benjamin Edginton-White, Kakkad Regha, Ella Kennett, Constanze Bonifer

    Sophie G Kellaway ... Constanze Bonifer

    Published 4 January 2021

    Using integrated genome-wide and phenotypic methods this study investigates four different mutant RUNX1 oncoproteins and reveals how they differentially contribute to aberrant haematopoiesis.

View more latest articles

About Life Science Alliance

Life Science Alliance is an international, open-access, editorially independent, and peer-reviewed journal launched by an alliance of three preeminent scientific organizations: EMBO, Rockefeller University, and Cold Spring Harbor Laboratory. Life Science Alliance is committed to the rapid, fair, and transparent publication of research papers, resources, and new methods from the full spectrum of life science and biomedical research.

Life Science Alliance LLC is limited liability non-stock corporation jointly owned by Cold Spring Harbor Laboratory, EMBO Press Innovations gGmbH and The Rockefeller University and incorporated in the State of Delaware, USA, with company number 6706208.

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Volume 3, No. 12
December 2020
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