Newest Articles
Molecular mechanism of bacteriophage contraction structure of an S-layer–penetrating bacteriophageThis study describes the high-resolution cryoEM structure of a contractile bacteriophage, displaying reduced contraction and lack of enzymatic domains for penetration.
Rapid ER remodeling induced by a peptide–lipid complex in dying tumor cellsAlpha1-oleate induces novel ER remodeling, causing peripheral ER loss, vesiculation, and nuclear entry, expanding the nuclear ER with its content of dying cell debris.
Antibodies targeting ADAM17 reverse neurite outgrowth inhibition by myelin-associated inhibitorsInhibitory anti-ADAM17 monoclonal antibodies (mAbs) abrogate the cleavage of p75 in a neuroblastoma-glioma cell line.
Divergent Plasmodium kinases drive MTOC, kinetochore and axoneme organisation in male gametogenesisThis study reveals how Plasmodium kinases regulate MTOC, axoneme, and kinetochore organisation in male gametogenesis, providing key insights into potential targets for malaria transmission control.
Cytokine storm and vascular leakage in severe dengue: insights from single-cell RNA profilingFixed single-cell RNA profiling identified IL-17A/F-producing γδ T cells, ILC3s, and Th17 cells, cooperative roles of M1- and M2-like macrophages, and dual roles of neutrophils during severe dengue.
TPX2 lactylation is required for the cell cycle regulation and hepatocellular carcinoma progressionThis study identifies TPX2 lactylation as a critical regulator of hepatocellular carcinoma progression, linking metabolic reprogramming to cell cycle dysregulation.
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