Newest Articles
Small intestinal flora graft alters fecal flora, stool, cytokines and mood status in healthy miceTransplantation of microbiota from small intestine, not large intestine, of healthy mice exerts obvious effects on healthy recipients, bringing a new perspective on gut flora transplantation.
Sequencing of a central nervous system tumor demonstrates cancer transmission in an organ transplantThis study uses DNA sequencing to trace a donor organ transplant–mediated cancer transmission and illustrates how precise molecular pathology profiles might reduce future risk for transplant recipients.
Hepatitis B virus compartmentalization and single-cell differentiation in hepatocellular carcinomaSingle-cell RNA-Seq unravels heterogeneity and compartmentalization of both hepatitis B virus and cancer identifying new candidate pathways for viral hepatocarcinogenesis.
Functional annotation of noncoding mutations in cancerRecurrent regulatory mutations affecting transcription factor binding sites in 2,500 cancer samples.
Exosome-mediated delivery of CRISPR/Cas9 for targeting of oncogenic KrasG12D in pancreatic cancerThis work identifies the use of exosomes to specifically deliver CRISPR/Cas9 to target oncogenic KrasG12D mutation in pancreatic cancer as a nonviral therapeutic strategy.
Heterogeneous nuclear ribonucleoprotein E1 binds polycytosine DNA and monitors genome integrityhnRNP E1 binds polycytosine tracts of DNA and monitors genome integrity.
About Life Science Alliance
Life Science Alliance is an international, open-access, editorially independent, and peer-reviewed journal launched by an alliance of three preeminent scientific organizations: EMBO, Rockefeller University, and Cold Spring Harbor Laboratory. Life Science Alliance is committed to the rapid, fair, and transparent publication of research papers, resources, and new methods from the full spectrum of life science and biomedical research.
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