Newest Articles
Novel imaging tools to study mitochondrial morphology in Caenorhabditis elegansThis study presents novel genetic tools for live imaging of mitochondrial morphology in the nematode Caenorhabditis elegans, offering insights into mitochondrial dynamics and providing a thorough comparison with existing methods.
Structural roles of Ump1 and β-subunit propeptides in proteasome biogenesisA 2.1 Å cryo-EM structure of a late proteasome precursor reveals roles of the assembly chaperone Ump1 and β-subunit propeptides in proteasome biogenesis.
Non-redundant roles for the human mRNA decapping cofactor paralogs DCP1a and DCP1bThe study represents the first functional dissection of the two human cofactors present in the RNA decapping complex, and, significantly, it evaluates their role in the transcript buffering system.
Mast cell extracellular trap formation underlies vascular and neural injury and hyperalgesia in sickle cell diseaseMast cell extracellular traps catalyzed by peptidylarginine deiminase 4 contribute to vascular stasis and nerve injury, which may contribute to acute and chronic pain in sickle cell disease.
Regulation of proteostasis by sleep through autophagy in Drosophila models of Alzheimer’s diseaseSleep modulation alters Tau-induced neurodegeneration in Drosophila models of tauopathy.
Cell-Int: a cell–cell interaction assay to identify native membrane protein interactionsA cell interaction assay to study membrane protein interactions in quasi-physiological settings, with multiple applications, from deciphering interaction networks to assessing therapeutic molecules.
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