It has been shown recently that MCs are required for differential regulation of the immune
response by granulocytic versus monocytic MDSCs. Granulocytic MDSCs promoted parasite …

The proper regulation of ICOS and ICOS ligand (ICOSL) has been shown to be essential for
maintaining proper immune homeostasis. Loss of either protein results in defective humoral …

Adoptive T cell immunotherapy is a promising approach to cancer treatment that currently
has limited clinical applications. DNA methyltransferase inhibitors (DNAMTi) have known …

Intracellular bacteria that live in host cell–derived vacuoles are significant causes of human
disease. Parasitism of low-density lipoprotein (LDL) cholesterol is essential for many vacuole…

Background Myeloid derived suppressor cells (MDSCs) present a significant obstacle to
cancer immunotherapy because they dampen anti-tumor cytotoxic T cell responses. Previous …

Helminth infection is known for generating large amounts of poly-specific IgE. Here we
demonstrate that innate-like B1 cells are responsible for this IgE production during infection with …

The serum methotrexate (MTX) concentrations were estimated in two groups of patients
after 6-hour iv infusion of 1 g/m² of MTX and leucovorin rescue. One group (seven patients) …

… Data correlation was performed using Pearson’sr for continuous data comparisons and
with Spearman’s ρ when one or both data sets were non-continuous (SPSS). Testing of …

ADAM10 and Notch1 on murine dendritic cells control the development of type 2 immunity
and IgE production - Damle - 2018 - Allergy - Wiley Online Library … SR Damle …

Infections with helminth parasites are endemic in the developing world and are a target for
intervention with new therapies. Macrophage migration inhibitory factor (MIF) is a cytokine …